Biomarkers to Predict Rotator Cuff Repair Healing on Postoperative MRI
for Rotator Cuff Tears
1 location in Iowa City
Sponsor: Joseph W. Galvin
Sex: All·Age: 18 - 99
Code: NCT07781553·Recruiting·Listed Aug 24, 2026
Clinical Trials at University of Iowa
As of September 2026, 169 paid clinical trials are recruiting at University of Iowa, located at 200 HAWKINS DR, IOWA CITY, IA 52242, phone (319) 356-1616 in Iowa City, Iowa. Active studies at this site cover conditions such as Acute Myeloid Leukemia, Breast Cancer and Multiple Myeloma. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
View the full facility profile →
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Iowa City
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study in Young People and Adults to Learn About the Medicine Ritlecitinib for Treatment of Patchy Hair Loss, Known by the Medical Term as Moderate Alopecia Areata
for Alopecia Areata
Drug: Ritlecitinib
Sites in Iowa City +15 more locations
Sponsor: Pfizer
Sex: All·Age: 12+
Code: NCT07733765·Phase 3·Recruiting·Listed Jul 29, 2026
Antidepressant Therapy for Improved Blood Vessel Health After Preeclampsia
for Preeclampsia
1 location in Iowa City
Sponsor: Anna Stanhewicz, PhD
Sex: Female·Age: 18 - 45·Accepts healthy volunteers
Code: NCT07715669·EARLY_Phase 1·Recruiting·Listed Jul 20, 2026
172 clinical trials at University of Iowa
·Clear filters· Get a weekly email when new trials open in Iowa City, IA.
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
for Obesity
Drug: NNC0487-0111
Sites in Iowa City, Davenport +204 more locations
Sponsor: Novo Nordisk A/S
Sex: All·Age: 18+
Code: NCT07567001·Phase 3·Recruiting·Listed May 2026
Phase 2 Study to Assess the Safety and Efficacy of ANG003
for Exocrine Pancreatic Insufficiency (EPI)
Sites in Iowa City +25 more locations
Sponsor: Anagram Therapeutics, Inc.
Sex: All·Age: 12+
Code: NCT07450547·Phase 2·Recruiting·Listed Mar 2026
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
for Breast Neoplasms
Sites in Iowa City +124 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07174336·Phase 3·Recruiting·Listed Sep 2025
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
for Large B-cell Lymphoma
Sites in Iowa City +35 more locations
Sponsor: Lyell Immunopharma, Inc.
Sex: All·Age: 18+
Code: NCT07188558·Phase 3·Recruiting·Listed Sep 2025
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
for Colon Adenocarcinoma
Drug: Calderasib
Sites in Iowa City +38 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06997497·Phase 3·Recruiting·Listed May 2025
Assessment of CCM in HF With Higher Ejection Fraction
for Heart Failure
Sites in Iowa City, West Des Moines +74 more locations
Sponsor: Impulse Dynamics
Sex: All·Age: 18+
Code: NCT05064709·Recruiting·Listed Oct 2021
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
for Acute Myeloid Leukemia (AML)
Sites in Iowa City +41 more locations
Sponsor: Kura Oncology, Inc.
Sex: All·Age: 18+
Code: NCT07007312·Phase 3·Recruiting·Listed Jun 2025
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
for Non-Small Cell Lung Cancer
Drug: Divarasib
Sites in Iowa City, Des Moines +52 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 18+
Code: NCT06793215·Phase 3·Recruiting·Listed Jan 2025
A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
for Endometrial Adenocarcinoma
Sites in Iowa City +41 more locations
Sponsor: Acrivon Therapeutics
Sex: Female·Age: 18+
Code: NCT05548296·Phase 2·Recruiting·Listed Sep 2022
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
for Autosomal Dominant Polycystic Kidney Disease
Sites in Iowa City +36 more locations
Sponsor: Calico Life Sciences LLC
Sex: All·Age: 18 - 55
Code: NCT06902558·Phase 2·Recruiting·Listed Mar 2025
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
for Relapsed Non-Hodgkin Lymphoma
Sites in Iowa City +31 more locations
Sponsor: Lyell Immunopharma, Inc.
Sex: All·Age: 18+
Code: NCT05826535·Phase 1, Phase 2·Recruiting·Listed Apr 2023
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]
for Advanced Melanoma
Drug: Nivolumab
Sites in Iowa City +43 more locations
Sponsor: Replimune, Inc.
Sex: All·Age: 12+
Code: NCT06264180·Phase 3·Recruiting·Listed Feb 2024
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
for Non-cystic Fibrosis Bronchiectasis
Sites in Iowa City +27 more locations
Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
Sex: All·Age: 18 - 80
Code: NCT06559150·Phase 2·Recruiting·Listed Aug 2024
Pompe Disease Registry Protocol
for Glycogen Storage Disease Type II
Sites in Iowa City +73 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00231400·Recruiting·Listed Oct 2005
Fabry Disease Registry & Pregnancy Sub-registry
for Fabry Disease
Sites in Iowa City +73 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00196742·Recruiting·Listed Sep 2005
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
for Breast Cancer
Sites in Iowa City +23 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT05768139·Phase 1, Phase 2·Recruiting·Listed Mar 2023
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
for Carcinoma, Non-Small-Cell Lung
Sites in Iowa City +24 more locations
Sponsor: Seagen, a wholly owned subsidiary of Pfizer
Sex: All·Age: 18+
Code: NCT05208762·Phase 1·Recruiting·Listed Jan 2022
A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction
for Lung Transplant Rejection
Sites in Iowa City +31 more locations
Sponsor: Sanofi
Sex: All·Age: 18+
Code: NCT06082037·Phase 3·Recruiting·Listed Oct 2023
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
for Multiple Myeloma
Sites in Iowa City +37 more locations
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Sex: All·Age: 18+
Code: NCT06297226·Phase 2·Recruiting·Listed Mar 2024
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
for Gaucher Disease
Sites in Iowa City +69 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00358943·Recruiting·Listed Aug 2006
A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
for Metastatic Uveal Melanoma
Drug: Nivolumab
Sites in Iowa City +28 more locations
Sponsor: Replimune, Inc.
Sex: All·Age: All ages
Code: NCT06581406·Phase 2, Phase 3·Recruiting·Listed Sep 2024
GEMINI-NSCLC: NSCLC Biomarker Study
for Non-Small Cell Lung Cancer
Sites in Iowa City +55 more locations
Sponsor: Tempus AI
Sex: All·Age: 18+
Code: NCT05236114·Recruiting·Listed Feb 2022
A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
for Gastrointestinal Stromal Tumor (GIST)
Sites in Iowa City +31 more locations
Sponsor: Kura Oncology, Inc.
Sex: All·Age: 18+
Code: NCT06655246·Phase 1·Recruiting·Listed Oct 2024
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
for Spinal Muscular Atrophy (SMA)
Sites in Iowa City +41 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: All ages
Code: NCT04174157·Recruiting·Listed Nov 2019
A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
for Multiple Myeloma
Sites in Iowa City +19 more locations
Sponsor: C4 Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT07284758·Phase 2·Recruiting·Listed Dec 2025
A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)
for Chronic Lymphocytic Leukemia (CLL)
Sites in Iowa City +24 more locations
Sponsor: Nurix Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT07221500·Phase 2·Recruiting·Listed Oct 2025
A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults
for Hearing Loss, Bilateral Sensorineural
Sites in Iowa City +10 more locations
Sponsor: Cochlear
Sex: All·Age: 18+
Code: NCT07287124·Recruiting·Listed Dec 2025
A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
for HR+ Breast Cancer
Sites in Iowa City +17 more locations
Sponsor: NiKang Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT07029399·Phase 1·Recruiting·Listed Jun 2025
A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )
for Lymphoma, Non-Hodgkin
Sites in Iowa City +22 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07101328·Phase 1·Recruiting·Listed Aug 2025
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma
for Lymphoma
Drug: Glofitamab
Sites in Iowa City, Waukee +18 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 18+
Code: NCT06084936·Phase 3·Recruiting·Listed Oct 2023
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
for PIK3CA-Related Overgrowth Spectrum (PROS)
Sites in Iowa City +21 more locations
Sponsor: Relay Therapeutics, Inc.
Sex: All·Age: 2+
Code: NCT06789913·Phase 2·Recruiting·Listed Jan 2025
A Phase 1 Study of IM-1021 in Participants With Advanced Cancer
for Solid Malignancies
Sites in Iowa City +18 more locations
Sponsor: Immunome, Inc.
Sex: All·Age: 18+
Code: NCT06823167·Phase 1·Recruiting·Listed Feb 2025
A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment
for Noonan Syndrome
Drug: Vosoritide
Sites in Iowa City +19 more locations
Sponsor: BioMarin Pharmaceutical
Sex: All·Age: 3 - 11
Code: NCT06668805·Phase 2·Recruiting·Listed Oct 2024
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
for Neutropenia
Sites in Iowa City +20 more locations
Sponsor: X4 Pharmaceuticals
Sex: All·Age: 12+
Code: NCT06056297·Phase 3·Recruiting·Listed Sep 2023
The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms
for Hemorrhagic Stroke
Sites in Iowa City +21 more locations
Sponsor: phenox Inc.
Sex: All·Age: 18+
Code: NCT07143019·Recruiting·Listed Aug 2025
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
for Cervical Cancer
Sites in Iowa City +7 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT04895709·Phase 1, Phase 2·Recruiting·Listed May 2021
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
for Gastric or Gastroesophageal Junction Adenocarcinoma
Sites in Iowa City +9 more locations
Sponsor: Phanes Therapeutics
Sex: All·Age: 18+
Code: NCT05482893·Phase 1, Phase 2·Recruiting·Listed Aug 2022
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
for Pheochromocytoma/Paraganglioma
Sites in Iowa City +10 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 12+
Code: NCT04924075·Phase 2·Recruiting·Listed Jun 2021
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
for Systemic Lupus Erythematosus (With and Without Nephritis)
Sites in Iowa City +13 more locations
Sponsor: Allogene Therapeutics
Sex: All·Age: 18 - 74
Code: NCT07085104·Phase 1·Recruiting·Listed Jul 2025
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis
for Scleroderma, Diffuse
Sites in Iowa City +13 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18 - 70
Code: NCT06655896·Phase 2·Recruiting·Listed Oct 2024
Common conditions studied in Iowa City
- Acute Myeloid Leukemia (11 active studies)
- Breast Cancer (11 active studies)
- Multiple Myeloma (8 active studies)
- Hearing Loss, Sensorineural (5 active studies)
- Non-Hodgkin Lymphoma (5 active studies)
- Bladder Cancer (4 active studies)
Leading research sponsors in Iowa City
- University of Iowa
- National Cancer Institute (NCI)
- Children's Oncology Group
- Novartis Pharmaceuticals
- Anna Stanhewicz, PhD
Frequently asked questions
How many paid clinical trials are currently recruiting in Iowa City?
There are approximately 553 recruiting clinical trials in Iowa City, Iowa listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Iowa City pay participants?
Most recruiting trials in Iowa City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Iowa City?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Iowa City?
The most common conditions under active study in Iowa City include Acute Myeloid Leukemia (11), Breast Cancer (11), Multiple Myeloma (8), Hearing Loss, Sensorineural (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Iowa City?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Iowa City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Iowa City?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Iowa City?
Recruiting research sites in Iowa City include University of Iowa, University of Iowa/Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Iowa City right now?
The largest active categories in Iowa City are Cancer & tumors (178), Neurology & pain (32), Cardiovascular (27). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of University of Iowa?
University of Iowa is located at 200 HAWKINS DR, IOWA CITY, IA 52242. Use the Google Maps link in the intro above to get directions.
How do I contact University of Iowa?
You can reach University of Iowa by phone at (319) 356-1616. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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