Exercise Oncology Clinic Pilot Feasibility Trial
for Breast Cancer
1 location in Iowa City
Sponsor: Jess S. Gorzelitz
Sex: All·Age: 18+
Code: NCT07765927·Recruiting·Listed Aug 14, 2026
Clinical Trials at University of Iowa Health Care
As of September 2026, 43 paid clinical trials are recruiting at University of Iowa Health Care in Iowa City, Iowa. Active studies at this site cover conditions such as Acute Myeloid Leukemia, Breast Cancer and Multiple Myeloma. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Iowa City
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
44 clinical trials at University of Iowa Health Care
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A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer
for Non-muscle Invasive Bladder Cancer
Sites in Iowa City +53 more locations
Sponsor: Pfizer
Sex: All·Age: 18+
Code: NCT07206225·Phase 1·Recruiting·Listed Oct 2025
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
for Advanced Breast Cancer
Sites in Iowa City +36 more locations
Sponsor: Stemline Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06638307·Phase 1·Recruiting·Listed Oct 2024
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
for Mesial Temporal Lobe Epilepsy
Sites in Iowa City +34 more locations
Sponsor: Neurona Therapeutics
Sex: All·Age: 18 - 75
Code: NCT05135091·Phase 3·Recruiting·Listed Nov 2021
Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease
for Moderately to Severely Active Crohn Disease
Sites in Iowa City +42 more locations
Sponsor: Abivax S.A.
Sex: All·Age: 18 - 75
Code: NCT06456593·Phase 2·Recruiting·Listed Jun 2024
KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)
for GIST - Gastrointestinal Stromal Tumor
Sites in Iowa City +16 more locations
Sponsor: Kumquat Biosciences Inc.
Sex: All·Age: 18+
Code: NCT07406633·Phase 2·Recruiting·Listed Feb 2026
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
for Huntington Disease
Sites in Iowa City +33 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 21 - 70
Code: NCT07326709·Phase 3·Recruiting·Listed Jan 2026
A Gaucher Disease Gene Therapy Trial With FLT201
for Gaucher Disease Type 1
Sites in Iowa City +15 more locations
Sponsor: Spur Therapeutics
Sex: All·Age: 18+
Code: NCT07223944·Phase 3·Recruiting·Listed Nov 2025
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
for Carcinoid Syndrome
Sites in Iowa City +16 more locations
Sponsor: Crinetics Pharmaceuticals Inc.
Sex: All·Age: 18+
Code: NCT07087054·Phase 3·Recruiting·Listed Jul 2025
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
for Central Line Associated Blood Stream Infections (CLABSI)
Sites in Iowa City +15 more locations
Sponsor: CorMedix Therapeutics
Sex: All·Age: 18+
Code: NCT06822426·Phase 3·Recruiting·Listed Feb 2025
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
for C3G
Drug: Iptacopan
Sites in Iowa City +4 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 12 - 60
Code: NCT04817618·Phase 3·Recruiting·Listed Mar 2021
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
for Lower Respiratory Tract Infection
Sites in Iowa City +18 more locations
Sponsor: Ansun Biopharma, Inc.
Sex: All·Age: All ages
Code: NCT03808922·Phase 3·Recruiting·Listed Jan 2019
Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
for PDAC
Sites in Iowa City +17 more locations
Sponsor: Tango Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06922591·Phase 1, Phase 2·Recruiting·Listed Apr 2025
Myriad™ Augmented Soft Tissue Reconstruction Registry
for Abdominal Wound Dehiscence
Sites in Iowa City +11 more locations
Sponsor: Aroa Biosurgery Limited
Sex: All·Age: 18+
Code: NCT05243966·Recruiting·Listed Feb 2022
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
for Epilepsy, Temporal Lobe
Sites in Iowa City +15 more locations
Sponsor: Neurona Therapeutics
Sex: All·Age: 18 - 75
Code: NCT06422923·Phase 1, Phase 2·Recruiting·Listed May 2024
Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy
for Down Syndrome
Sites in Iowa City +11 more locations
Sponsor: Sequenom, Inc.
Sex: Female·Age: 18+
Code: NCT01429389·Recruiting·Listed Sep 2011
A Study of TORL-5-700 in Relapsed/Refractory Non Hodgkin's Lymphoma
for Histologically Confirmed Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Sites in Iowa City +5 more locations
Sponsor: TORL Biotherapeutics, LLC
Sex: All·Age: 18+
Code: NCT07439653·Phase 1, Phase 2·Recruiting·Listed Feb 2026
Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN
for C3 Glomerulopathy
Drug: Iptacopan
Sites in Iowa City +4 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 12 - 100
Code: NCT03955445·Phase 3·Recruiting·Listed May 2019
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
for Cervical Cancer
Sites in Iowa City +6 more locations
Sponsor: Orano Med Theranostics, SAS
Sex: All·Age: 18+
Code: NCT05283330·Phase 1·Recruiting·Listed Mar 2022
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
for Burns
Sites in Iowa City +3 more locations
Sponsor: Skingenix, Inc.
Sex: All·Age: 18+
Code: NCT01297400·Phase 2·Recruiting·Listed Feb 2011
Duchenne Electronic Health Record Study
for Duchenne Muscular Dystrophy (DMD)
Sites in Iowa City +9 more locations
Sponsor: The Duchenne Registry
Sex: All·Age: All ages
Code: NCT07609394·Recruiting·Listed May 2026
Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody Efficacy in Multiple Myeloma
for Multiple Myeloma
1 location in Iowa City
Sponsor: Christopher Strouse
Sex: All·Age: 18+
Code: NCT07581704·Phase 1·Recruiting·Listed May 2026
Sitagliptin in Recurrent/Progressive Grade 4 Glioma
for Glioma
1 location in Iowa City
Sponsor: Kailin Yang, MD, PhD
Sex: All·Age: 18+
Code: NCT07541781·Phase 1·Recruiting·Listed Apr 2026
5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors
for Solid Tumor
1 location in Iowa City
Sponsor: Mohammed Milhem
Sex: All·Age: 18 - 99
Code: NCT07404332·Phase 1·Recruiting·Listed Feb 2026
T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas
for Malignant Glioma
1 location in Iowa City
Sponsor: John M. Buatti
Sex: All·Age: 21+
Code: NCT07447531·Recruiting·Listed Mar 2026
High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML)
for Acute Myeloid Leukemia
Drug: Venetoclax
1 location in Iowa City
Sponsor: Kittika Poonsombudlert
Sex: All·Age: 18 - 75
Code: NCT07177079·Phase 1·Recruiting·Listed Sep 2025
PERceptions of Diltiazem Versus ADEnosine for Treatment of Supraventricular Tachycardia in the Emergency Department
for Supraventricular Tachycardia (SVT)
1 location in Iowa City
Sponsor: University of Iowa
Sex: All·Age: 18 - 100
Code: NCT07086560·Recruiting·Listed Jul 2025
Evaluation of Pirfenidone as a Novel Therapeutic Strategy Against Recurrent Acute Pancreatitis.
for Recurrent Acute Pancreatitis
Sites in Iowa City +2 more locations
Sponsor: University of Alabama at Birmingham
Sex: All·Age: 18 - 85
Code: NCT06253117·Phase 2·Recruiting·Listed Feb 2024
Adenosine vs Diltiazem for Treatment of SVT in the ED
for Supraventricular Tachycardia (SVT)
1 location in Iowa City
Sponsor: Anne E. Zepeski
Sex: All·Age: 18 - 100
Code: NCT06993038·Phase 4·Recruiting·Listed May 2025
Ketamine Alcohol (in Treatment-Resistant Depression)
for Magnetic Resonance Imaging
1 location in Iowa City
Sponsor: Mark Niciu
Sex: All·Age: 18 - 55
Code: NCT02122562·Phase 2·Recruiting·Listed Apr 2014
IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia
for Laparotomy
1 location in Iowa City
Sponsor: University of Iowa
Sex: All·Age: 18 - 85
Code: NCT06559969·Phase 2, Phase 3·Recruiting·Listed Aug 2024
Genetic Risk Factor for Heat Stroke
for Carrier State
1 location in Iowa City
Sponsor: University of Iowa
Sex: All·Age: 18 - 60
Code: NCT06847256·Recruiting·Listed Feb 2025
University of Iowa Interventional Psychiatry Service Patient Registry
for Treatment Resistant Depression
1 location in Iowa City
Sponsor: Mark Niciu
Sex: All·Age: 18 - 99
Code: NCT04480918·Recruiting·Listed Jul 2020
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
for Alcohol Use Disorder
1 location in Iowa City
Sponsor: University of Iowa
Sex: All·Age: 21 - 65
Code: NCT06405607·Phase 2·Recruiting·Listed May 2024
SMBP Study: Improving High Blood Pressure in Older Adults With Multiple Chronic Diseases
for Hypertension
2 locations in Iowa City
Sponsor: Korey Kennelty
Sex: All·Age: 65+
Code: NCT06932029·Recruiting·Listed Apr 2025
The Heartland Study
for Pregnancy Related
Sites in Iowa City +2 more locations
Sponsor: Heartland Health Research Alliance
Sex: Female·Age: 18+·Accepts healthy volunteers
Code: NCT05492708·Recruiting·Listed Aug 2022
Mirikizumab Real World Protocol
for Ulcerative Colitis
Sites in Iowa City +7 more locations
Sponsor: University of North Carolina, Chapel Hill
Sex: All·Age: 18+
Code: NCT06696014·Recruiting·Listed Nov 2024
Objectively Diagnose and Monitor Treatment of Light Sensitivity
for Photophobia
1 location in Iowa City
Sponsor: Randy Kardon
Sex: All·Age: 18 - 80·Accepts healthy volunteers
Code: NCT03694626·Recruiting·Listed Oct 2018
Outcomes of Limited Postoperative Restrictions Following Sling Placement: A Randomized Controlled Trial
for Postoperative Restriction
1 location in Iowa City
Sponsor: University of Iowa
Sex: Female·Age: 18 - 99
Code: NCT06840093·Recruiting·Listed Feb 2025
Can PLIA Reduce Early Post-operative Pain After PAO Surgery?
for Hip Dysplasia
1 location in Iowa City
Sponsor: Michael C Willey
Sex: All·Age: 13 - 50·Accepts healthy volunteers
Code: NCT06519955·Phase 2, Phase 3·Recruiting·Listed Jul 2024
Essential Amino Acid Supplementation for Femoral Fragility Fractures
for Femoral Fracture
Sites in Iowa City +1 more location
Sponsor: Michael C Willey
Sex: All·Age: 65+
Code: NCT06050668·Phase 2·Recruiting·Listed Sep 2023
Common conditions studied in Iowa City
- Acute Myeloid Leukemia (11 active studies)
- Breast Cancer (11 active studies)
- Multiple Myeloma (8 active studies)
- Hearing Loss, Sensorineural (5 active studies)
- Non-Hodgkin Lymphoma (5 active studies)
- Bladder Cancer (4 active studies)
Leading research sponsors in Iowa City
- University of Iowa
- National Cancer Institute (NCI)
- Children's Oncology Group
- Novartis Pharmaceuticals
- Anna Stanhewicz, PhD
Frequently asked questions
How many paid clinical trials are currently recruiting in Iowa City?
There are approximately 553 recruiting clinical trials in Iowa City, Iowa listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Iowa City pay participants?
Most recruiting trials in Iowa City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Iowa City?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Iowa City?
The most common conditions under active study in Iowa City include Acute Myeloid Leukemia (11), Breast Cancer (11), Multiple Myeloma (8), Hearing Loss, Sensorineural (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Iowa City?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Iowa City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Iowa City?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Iowa City?
Recruiting research sites in Iowa City include University of Iowa, University of Iowa/Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Iowa City right now?
The largest active categories in Iowa City are Cancer & tumors (178), Neurology & pain (32), Cardiovascular (27). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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