Paid Clinical Trials in Iowa City, IA

As of August 2026, 554 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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510 clinical trials

Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

for Congenital Myotonic Dystrophy

Sites in Iowa City +7 more locations

Sponsor: AMO Pharma Limited

Sex: All·Age: 6 - 45

Code: NCT05004129·Phase 2, Phase 3·Recruiting·Listed Aug 2021

Apply to this trial

MB-105 in Patients With CD5 Positive T-cell Lymphoma

for Lymphoma, T-Cell

Sites in Iowa City +11 more locations

Sponsor: March Biosciences Inc

Sex: All·Age: 18+

Code: NCT06534060·Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

Treatment of Moderate to Severe Refractory Crohn's Disease

for Crohns Disease

Sites in Iowa City +12 more locations

Sponsor: Tr1X, Inc.

Sex: All·Age: 18 - 65

Code: NCT06721962·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

Sites in Iowa City +21 more locations

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting·Listed May 2023

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Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

for Down Syndrome

Sites in Iowa City +11 more locations

Sponsor: Sequenom, Inc.

Sex: Female·Age: 18+

Code: NCT01429389·Recruiting·Listed Sep 2011

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A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)

for Malignant Neoplasm

Sites in Iowa City +7 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 Month - 17

Code: NCT07630974·Phase 1, Phase 2·Recruiting·Listed Jun 2026

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Study of Intrathecal ELP-02 for Charcot-Marie-Tooth Disease Type 4J (CMT4J)

for Charcot-Marie-Tooth Disease Type 4J

Sites in Iowa City +1 more location

Sponsor: Elpida Therapeutics SPC

Sex: All·Age: 3 - 20

Code: NCT07447557·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

for Hemophilia A

Drug: NXT007

Sites in Iowa City +5 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 12+

Code: NCT07416604·Phase 3·Recruiting·Listed Feb 2026

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A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

Sites in Iowa City +5 more locations

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 18+

Code: NCT07287150·Phase 2·Recruiting·Listed Dec 2025

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AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)

for Metastatic Castration Resistant Prostate Cancer (mCRPC)

Sites in Iowa City +8 more locations

Sponsor: Arsenal Biosciences, Inc.

Sex: Male·Age: 18+

Code: NCT07285694·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

for Diabetes Mellitus, Type 1

Drug: Baricitinib

Sites in Iowa City, West Des Moines +4 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 1 - 35

Code: NCT07222137·Phase 3·Recruiting·Listed Oct 2025

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A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

for Haemophilia A

Sites in Iowa City +4 more locations

Sponsor: Novo Nordisk A/S

Sex: Male·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07220564·Phase 1·Recruiting·Listed Oct 2025

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A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

for Acute Myeloid Leukaemia (AML)

Sites in Iowa City +8 more locations

Sponsor: Tempus AI

Sex: All·Age: 0+

Code: NCT07154823·Recruiting·Listed Sep 2025

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A Study to Assess the Effects of Zigakibart on IgA Nephropathy.

for Immunoglobulin A Nephropathy (IgAN)

Sites in Iowa City +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07146906·Phase 2·Recruiting·Listed Aug 2025

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TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Drug: Tulmimetostat

Sites in Iowa City +7 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07190300·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

for GEP-NET

Sites in Iowa City +6 more locations

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT07165132·Phase 1·Recruiting·Listed Sep 2025

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A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease

for Fabry Disease

Sites in Iowa City +5 more locations

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: 2 - 17

Code: NCT06328608·Phase 2, Phase 3·Recruiting·Listed Mar 2024

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Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

for Small Cell Lung Carcinoma

Sites in Iowa City +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07006727·Phase 1·Recruiting·Listed Jun 2025

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A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

for SLE (Systemic Lupus)

Sites in Iowa City +6 more locations

Sponsor: CRISPR Therapeutics

Sex: All·Age: 18 - 70

Code: NCT06925542·Phase 1·Recruiting·Listed Apr 2025

Apply to this trial

NV PSR INSPIRE-A Pipeline™ Vantage Post Approval Study

for Intracranial Aneurysm

Sites in Iowa City +7 more locations

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 22+

Code: NCT06604884·Recruiting·Listed Sep 2024

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Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

for C3 Glomerulopathy

Drug: Iptacopan

Sites in Iowa City +4 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT03955445·Phase 3·Recruiting·Listed May 2019

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Study of Circular RNA Treatment in Patients With Radiation Induced Xerostomia-1

for Radiation-Induced Xerostomia and Hyposalivation

Sites in Iowa City +3 more locations

Sponsor: RiboX Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06714253·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array

for Sensorineural Hearing Loss

Sites in Iowa City +2 more locations

Sponsor: Cochlear

Sex: All·Age: 18+

Code: NCT06936449·Recruiting·Listed Apr 2025

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Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

for Cervical Cancer

Sites in Iowa City +6 more locations

Sponsor: Orano Med Theranostics, SAS

Sex: All·Age: 18+

Code: NCT05283330·Phase 1·Recruiting·Listed Mar 2022

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

for Hemophilia A

Drug: NXT007

Sites in Iowa City +2 more locations

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 2 - 59

Code: NCT05987449·Phase 1, Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

SPI-1005 in Adults Receiving Cochlear Implant

for Hearing Loss

Sites in Iowa City +5 more locations

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18+

Code: NCT06340633·Phase 2·Recruiting·Listed Apr 2024

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A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

for Solid Tumor

Sites in Iowa City +8 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT05584670·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

for Leber Congenital Amaurosis 10

Sites in Iowa City +4 more locations

Sponsor: Laboratoires Thea

Sex: All·Age: 6+

Code: NCT06891443·Phase 3·Recruiting·Listed Mar 2025

Apply to this trial

Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

for Hereditary Transthyretin-mediated (hATTR) Amyloidosis

1 location in Iowa City

Sponsor: Alnylam Pharmaceuticals

Sex: Female·Age: All ages

Code: NCT05040373·Recruiting·Listed Sep 2021

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BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer

for Hormone-receptor-positive Breast Cancer

Sites in Iowa City +2 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06756932·Phase 1·Recruiting·Listed Jan 2025

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An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

for Friedreich Ataxia

Sites in Iowa City +5 more locations

Sponsor: Larimar Therapeutics, Inc.

Sex: All·Age: 2 - 60

Code: NCT06447025·Phase 2·Recruiting·Listed Jun 2024

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Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

for Myotonic Dystrophy Type 1 (DM1)

Sites in Iowa City +7 more locations

Sponsor: Dyne Therapeutics

Sex: All·Age: 18 - 65

Code: NCT05481879·Phase 1, Phase 2·Recruiting·Listed Aug 2022

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Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

for Burns

Sites in Iowa City +3 more locations

Sponsor: Skingenix, Inc.

Sex: All·Age: 18+

Code: NCT01297400·Phase 2·Recruiting·Listed Feb 2011

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A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

for Limb Girdle Muscular Dystrophy

Sites in Iowa City +5 more locations

Sponsor: AskBio Inc

Sex: All·Age: 18 - 65

Code: NCT05230459·Phase 1, Phase 2·Recruiting·Listed Feb 2022

Apply to this trial

Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss

for Sensorineural Hearing Loss, Bilateral

Sites in Iowa City +5 more locations

Sponsor: Akouos, Inc.

Sex: All·Age: All ages

Code: NCT05821959·Phase 1, Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

Study of ATX-01 in Participants With DM1

for Myotonic Dystrophy 1

Sites in Iowa City +4 more locations

Sponsor: ARTHEx Biotech S.L.

Sex: All·Age: 18 - 64

Code: NCT06300307·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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Otoferlin Gene-mediated Hearing Loss Natural History Study

for Sensorineural Hearing Loss, Bilateral

Sites in Iowa City +3 more locations

Sponsor: Akouos, Inc.

Sex: All·Age: Up to 44

Code: NCT05572073·Recruiting·Listed Oct 2022

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A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSC

for Primary Sclerosing Cholangitis (PSC)

Sites in Iowa City +6 more locations

Sponsor: LISCure Biosciences

Sex: All·Age: 18 - 75

Code: NCT06699121·Phase 2·Recruiting·Listed Nov 2024

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Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy

for Factor VIII Deficiency

Sites in Iowa City +3 more locations

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT06941870·Phase 4·Recruiting·Listed Apr 2025

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Single-Sided Deafness and Asymmetric Hearing Loss

for Hearing Loss, Unilateral

Sites in Iowa City +2 more locations

Sponsor: Med-El Corporation

Sex: All·Age: 5+

Code: NCT04506853·Recruiting·Listed Aug 2020

Apply to this trial