Rheumatology Clinical Trials in Lincoln, NE
As of July 2026, 3 paid clinical trials are recruiting for Rheumatology in Lincoln, Nebraska. Rheumatology trials test new biologics, JAK inhibitors, and immune-modulating agents for rheumatoid arthritis, psoriatic arthritis, lupus, and other systemic autoimmune diseases. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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3 clinical trials for Rheumatology
·Clear filters·↓ Download CSVA Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab
Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
About research studies in Lincoln
Lincoln has approximately 126 recruiting research studies across a wide range of therapeutic areas. Nebraska hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Lincoln
Researchers run research studies in Lincoln, NE at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Bryan Heart | Obesity, Heart Failure, Heart Failure With Preserved Ejection Fraction | 10 |
| Cancer Partners of Nebraska | Stage IIIB Lung Cancer AJCC v8, Advanced Lung Non-Squamous Non-Small Cell Carcinoma, Advanced Non-Small Cell Lung Cancer | 9 |
| NHO Revive Research Institute, LLC | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 9 |
| Bryan Medical Center | Acute Respiratory Distress Syndrome, Bowel Resection, Colon Procedures | 6 |
| Celerion | Healthy Volunteer, Healthy, Healthy Adult Male and Female Volunteers | 6 |
| Somnos Clinical Research | Allergic Conjunctivitis, Amyotrophic Lateral Sclerosis, Chronic Spontaneous Urticaria (CSU) | 5 |
| Midwest Children's Health Research Institute | Pneumococcal Disease, Healthy | 3 |
| Alivation Research LLC | Autism Spectrum Disorder, Bipolar Depression, Bipolar Disorder | 3 |
| Nebraska Hematology-Oncology | Non-small Cell Lung Cancer (NSCLC), Follicular Lymphoma (FL), Non-Small Cell Lung Cancer | 3 |
| Physician Research Collaboration, LLC | Cardiovascular Disease, Psoriatic Arthritis, Atopic Dermatitis | 3 |
| GSK Investigational Site | Chickenpox | 2 |
| Alkermes Investigational Site | Bipolar I Disorder, Idiopathic Hypersomnia, Narcolepsy Type 1 | 2 |
| Alkermes Investigator Site | Bipolar I Disorder, Idiopathic Hypersomnia, Schizophrenia | 2 |
| Celerion, Inc. | Healthy Participants, Schizophrenia | 2 |
| NHO Revive Research Institute | Cancer Weight Loss, KRAS G12C Lung Cancer, Non-Small Cell Lung Cancer | 2 |
| Nebraska Heart Hospital | Coronary Artery Disease, Heart Diseases, Coronary Artery Bypass Grafting | 2 |
| Nebraska Hematology Oncology | Gastroesophageal Junction Adenocarcinoma, Metastatic Gastric Adenocarcinoma, Solid Tumor | 2 |
| Saint Elizabeth Regional Medical Center | Anatomic Stage IV Breast Cancer AJCC v8, Elevated CA15-3 or CEA or CA27-29, Estrogen Receptor Positive | 2 |
| University of Nebraska Medical Center College of Dentistry | Edentulism, Periodontal Inflammation | 2 |
| University of Nebraska-Lincoln | Alcohol Drinking, Cognitive Ability, General, Dietary Assessment | 2 |
| NHO Revive Research Institute LLC | Breast Cancer, Non-small Cell Lung Cancer | 2 |
| Nho - Revive Research Institute | Non-Squamous Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer | 2 |
| Midwest Children's Health Research Center | Healthy | 1 |
| Alivation Research | Bipolar I or II Disorder | 1 |
| Alivation Research, LLC | Treatment Resistant Depression | 1 |
Active & Upcoming Studies in Lincoln (2026)
Recruiting trials in Lincoln grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (39 active studies)
- A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015) · Phase 3 · Merck Sharp & Dohme LLC
- BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease · Phase 3 · BeOne Medicines
Cardiovascular (13 active studies)
Mental health & behavior (9 active studies)
- A Study to Detect the Radioactivity of 14C-SEP-380135 in Urine and Feces in Healthy Male Adults · Phase 1 · Otsuka Pharmaceutical Development & Commercialization, Inc.
- Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT) · Bristol-Myers Squibb
Diabetes & metabolic (9 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes · Medtronic MiniMed, Inc.
Neurology & pain (2 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Long-term Safety and Tolerability of BHV-7000 · Phase 2 · Biohaven Therapeutics Ltd.
Vaccines (1 active study)
- A Study of BLB-201 RSV Vaccine in Infants and Children · Phase 1, Phase 2 · Blue Lake Biotechnology Inc.
Common conditions studied in Lincoln
- Heart Failure (5 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Non-Small Cell Lung Cancer (5 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Schizophrenia (5 active studies). Schizophrenia research tests muscarinic agonists, long-acting injectable antipsychotics, and cognitive remediation therapies.
- Healthy (4 active studies). Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials.
- Non-small Cell Lung Cancer (4 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Breast Cancer (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Lincoln
- Merck Sharp & Dohme LLC
- AstraZeneca
- Pfizer
- AbbVie
- Alkermes, Inc.
Local regulations and guidelines
Clinical trials in Nebraska are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Nebraska research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Lincoln. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Lincoln
Hipa.ai aggregates every recruiting study in Lincoln from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Lincoln?
There are approximately 126 recruiting clinical trials in Lincoln, Nebraska listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Lincoln pay participants?
Most recruiting trials in Lincoln compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Lincoln?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Lincoln?
The most common conditions under active study in Lincoln include Heart Failure (5), Non-Small Cell Lung Cancer (5), Schizophrenia (5), Healthy (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Lincoln?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Lincoln on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Lincoln?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Lincoln?
Recruiting research sites in Lincoln include Bryan Heart, Cancer Partners of Nebraska, NHO Revive Research Institute, LLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Lincoln right now?
The largest active categories in Lincoln are Cancer & tumors (39), Cardiovascular (13), Mental health & behavior (9). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.