Oncology Clinical Trials in Little Rock, AR
As of August 2026, 75 paid clinical trials are recruiting for Oncology in Little Rock, Arkansas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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75 clinical trials for Oncology
·Clear filters·A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
Caris Biorepository Research Protocol
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.
Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors
Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]
A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer
A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
Clinical Evaluation of BCDx for Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer
PRGN-2009 in Combination With Pembrolizumab in Patients With Recurrent or Metastatic Cervical Cancer
Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
E-Mindfulness Approaches for Living After Breast Cancer
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
AI Algorithm-Informed Biopsy for Prostate Cancer Detection With Indeterminate and Low-Risk Prostate MRI Lesions
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
Top Research Study Locations in Little Rock
Researchers run research studies in Little Rock, AR at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Arkansas for Medical Sciences | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 105 |
| Arkansas Children's Hospital | Duchenne Muscular Dystrophy, Neuroblastoma, Acute Myeloid Leukemia | 91 |
| CARTI Cancer Center | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Plasma Cell Myeloma | 29 |
| Woodland International Research Group | Alcohol Use Disorder, Bipolar Depression, Bipolar Disorder | 13 |
| Arkansas Urology | Non-muscle Invasive Bladder Cancer, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ, Benign Prostatic Hyperplasia | 12 |
| Arkansas Children's Nutrition Center | Healthy, Adiposity, Blood Pressure | 10 |
| Applied Research Center of Arkansas | AIH, Autoimmune Hepatitis, COVID-19 SARS-CoV-2 Infection | 10 |
| Arkansas Children's Research Institute | Physical Activities, Duchene Muscular Dystrophy, High-grade Glioma | 8 |
| University of Arkansas | Breast Reconstruction, Cesarean Delivery, Diffuse Large B Cell Lymphoma (DLBCL) | 8 |
| Arkansas Heart Hospital | Acute Myocardial Infarction, Aortic Valve Disease, Aortic Valve Stenosis | 6 |
| Pillar Clinical Research- Little Rock | Schizophrenia, Bipolar Disorder, Bipolar Disorder Type I With Mania | 6 |
| Neurocrine Clinical Site | Major Depressive Disorder, Schizophrenia, Bipolar I Disorder | 5 |
| Pillar Clinical Research, LLC | Schizophrenia, Autism Spectrum Disorder, Bipolar Depression | 5 |
| Preferred Research Partners, Inc. | Attention-Deficit/Hyperactivity Disorder, Generalized Anxiety Disorder, Major Depressive Disorder | 5 |
| Arkansas Children's | B-Cell ALL, B-Cell Acute Lymphoblastic Leukaemia, B-Cell Lymphoblastic Leukemia | 4 |
| Arkansas Childrens Hospital | Duchenne Muscular Dystrophy, Medulloblastoma, Medulloblastoma, Non-WNT/Non-SHH | 4 |
| Lynn Institute of the Ozarks | Cardiovascular Disease, Diabetic Peripheral Neuropathic Pain, Difficult to Control Hypertension | 4 |
| Arkansas Cardiology | Cryptogenic Stroke, Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction | 3 |
| Arkansas Children's Hospital Research Institute | Cardiometabolic Health, Duchenne Muscular Dystrophy, Obesity | 3 |
| Arkansas Children's Hospital Research Institute: Department of Pediatrics, Allergy & Immunology | Allergy, Alpha-Gal Syndrome, Peanut Allergy | 3 |
| Arkansas Clinical Research | Acute Migraine, Migraine, Obesity | 3 |
| Baptist Health Medical Center - Little Rock | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 3 |
| Central Arkansas Veterans Healthcare System , Little Rock, AR | Carcinoma, Hepatocellular, Cirrhosis, Liver Diseases | 3 |
| Clinical Trials, Inc. | Focal Epilepsy, Focal Onset Seizures | 3 |
| GSK Investigational Site | Asthma, Influenza, Human+COVID-19, Non-alcoholic Fatty Liver Disease | 3 |
Active & Upcoming Studies in Little Rock (2026)
Recruiting trials in Little Rock grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (133 active studies)
- An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC · Phase 3 · AstraZeneca
- MMulti-Immune HR; Multi-Target Immunotherapy for High-Risk Multiple Myeloma · Phase 2 · University of Arkansas
Mental health & behavior (38 active studies)
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia · Phase 1 · Leal Therapeutics, Inc
Cardiovascular (30 active studies)
- Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation · Central Arkansas Veterans Healthcare System
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Diabetes & metabolic (27 active studies)
- Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women · University of Arkansas
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Neurology & pain (26 active studies)
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Pediatric (11 active studies)
- Longitudinal Prospective Study of Maternal and Child Nutrition in Arkansas · Arkansas Children's Hospital Research Institute
- How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants · University of Arkansas
Vaccines (4 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
- A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults · Phase 1 · GlaxoSmithKline
HIV / STI (1 active study)
- Universal Basic Income and Structural Racism in the US South: HIV Care · University of Arkansas
Common conditions studied in Little Rock
- Schizophrenia (16 active studies)
- Acute Myeloid Leukemia (11 active studies)
- Duchenne Muscular Dystrophy (10 active studies)
- Malignant Solid Neoplasm (8 active studies)
- Obesity (8 active studies)
- Bipolar I Disorder (7 active studies)
Leading research sponsors in Little Rock
- University of Arkansas
- National Cancer Institute (NCI)
- Arkansas Children's Hospital Research Institute
- Children's Oncology Group
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in Little Rock?
There are approximately 502 recruiting clinical trials in Little Rock, Arkansas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Little Rock pay participants?
Most recruiting trials in Little Rock compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Little Rock?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Little Rock?
The most common conditions under active study in Little Rock include Schizophrenia (16), Acute Myeloid Leukemia (11), Duchenne Muscular Dystrophy (10), Malignant Solid Neoplasm (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Little Rock?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Little Rock on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Little Rock?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Little Rock?
Recruiting research sites in Little Rock include University of Arkansas for Medical Sciences, Arkansas Children's Hospital, CARTI Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Little Rock right now?
The largest active categories in Little Rock are Cancer & tumors (133), Mental health & behavior (38), Cardiovascular (30). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.