Paid Clinical Trials in Littleton, CO
As of July 2026, 56 paid clinical trials are recruiting in Littleton, Colorado. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Littleton offers studies at sites including Rocky Mountain Cancer Centers-Littleton for conditions such as Breast Cancer, Atrial Fibrillation, Malignant Solid Neoplasm, Melanoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Littleton
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·Clear filters·Top Research Study Locations in Littleton
Researchers run research studies in Littleton, CO at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Rocky Mountain Cancer Centers-Littleton | Anatomic Stage IV Breast Cancer AJCC v8, Breast Carcinoma, Malignant Solid Neoplasm | 10 |
| South Denver Cardiology Associates | Atrial Fibrillation, Stroke, AV Block | 6 |
| AdventHealth Littleton | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 4 |
| Rocky Mountain Cancer Centers, LLP | Colorectal Neoplasms, Breast Cancer, Breast Neoplasms | 4 |
| Littleton Adventist Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Castration Levels of Testosterone, Elevated CA15-3 or CEA or CA27-29 | 3 |
| Rocky Mountain Gastroenterology | Colitis, Ulcerative, Moderately to Severely Active Crohns Disease, Primary Biliary Cholangitis (PBC) | 3 |
| South Denver Cardiology | Cardiovascular Diseases, Electrophysiology Study, Functional Mitral Regurgitation | 3 |
| South Denver Cardiology Associates, PC | Acute Myocardial Infarction, Coronary Arterial Disease (CAD), Persistent Atrial Fibrillation | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Rocky Mountain Cancer Centers | Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer, Metastatic Urothelial Cancer | 2 |
| Rocky Mountain Cancer Centers LLP | Breast Cancer, Non-Small Cell Lung Cancer Metastatic, Non-Small Cell Lung Carcinoma | 2 |
| Urology Associates | Prostate Cancer (Adenocarcinoma), Prostate Cancer Patients Treated by Radiotherapy, Carcinoma in Situ | 2 |
| Bloom Mental Health | Misophonia, Misophonia Treatment, Propanolol | 1 |
| Exelixis Clinical | Clear Cell Renal Cell Carcinoma (ccRCC), Colorectal Cancer (CRC), Head and Neck Squamous Cell Carcinoma (HNSCC) | 1 |
| Highline South Ambulatory Surgery Center, LLC | Lumbar Spinal Stenosis | 1 |
| Local Institution - 007-872-J | Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer | 1 |
| Massive Bio SYNERGY-AI site | BRCA Gene Rearrangement, Bladder Cancer, Breast Cancer | 1 |
| Mirador Therapeutics Selected Site | Crohn's Disease, Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC) | 1 |
| Rocky Mountain Cancer Center | Breast Cancer, Colorectal Cancer, Endometrial Cancer | 1 |
| Rocky Mountain Cancer Centers - Littleton | Breast Cancer | 1 |
| Rocky Mountain Endocopy Centers LLC | Crohn's Disease, Ulcerative Colitis | 1 |
| South Denver Cardiology Associates, P.C | Coronary Arterial Disease (CAD) | 1 |
| South Denver Cardiology Associates, P.C. | Atrial Fibrillation | 1 |
| Summit View Surgery Center | Lumbar Spinal Stenosis | 1 |
| UCHealth Primary Care - Sterling Ranch | Obesity | 1 |
Active & Upcoming Studies in Littleton (2026)
Recruiting trials in Littleton grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (26 active studies)
- Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer · Phase 2, Phase 3 · Pfizer
- A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec · Phase 2 · Candel Therapeutics, Inc.
Cardiovascular (9 active studies)
- AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions · Boston Scientific Corporation
- Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System · Boston Scientific Corporation
Diabetes & metabolic (3 active studies)
Neurology & pain (2 active studies)
Vaccines (1 active study)
Common conditions studied in Littleton
- Breast Cancer (5 active studies)
- Atrial Fibrillation (3 active studies)
- Malignant Solid Neoplasm (3 active studies)
- Melanoma (3 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (2 active studies)
Leading research sponsors in Littleton
- Pfizer
- SWOG Cancer Research Network
- ECOG-ACRIN Cancer Research Group
- 89bio, Inc.
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Littleton?
There are approximately 56 recruiting clinical trials in Littleton, Colorado listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Littleton pay participants?
Most recruiting trials in Littleton compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Littleton?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Littleton?
The most common conditions under active study in Littleton include Breast Cancer (5), Atrial Fibrillation (3), Malignant Solid Neoplasm (3), Melanoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Littleton?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Littleton on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Littleton?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Littleton?
Recruiting research sites in Littleton include Rocky Mountain Cancer Centers-Littleton, South Denver Cardiology Associates, AdventHealth Littleton, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Littleton right now?
The largest active categories in Littleton are Cancer & tumors (26), Cardiovascular (9), Diabetes & metabolic (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.