Non-small cell lung cancer (NSCLC) Clinical Trials in Los Angeles, CA

As of September 2026, 63 paid clinical trials are recruiting for Non-small cell lung cancer (NSCLC) in Los Angeles, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

Related specialties in Los Angeles

Oncology· 811 Lung oncology· 89

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64 clinical trials for Non-small cell lung cancer (NSCLC)

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Email me when a new non-small cell lung cancer (nsclc) trial opens in Los Angeles, CA.

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

for High-grade Serous Ovarian Carcinoma (HGSOC)

Sites in Los Angeles +4 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06476808·Phase 1·Recruiting·Listed Jun 2024

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A Study of VET3-TGI in Patients With Solid Tumors

for Solid Tumor, Adult

Sites in Los Angeles, Orange +5 more locations

Sponsor: KaliVir Immunotherapeutics

Sex: All·Age: 18+

Code: NCT06444815·Phase 1·Recruiting·Listed Jun 2024

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A Study of MT-4561 in Patients With Various Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma (HNSCC)

Sites in Los Angeles +3 more locations

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT06943521·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for Advanced Solid Tumor

Sites in Los Angeles, Fullerton +7 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT05103683·Phase 1·Recruiting·Listed Nov 2021

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APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for Solid Tumors

Sites in Los Angeles +3 more locations

Sponsor: Apollomics Inc.

Sex: All·Age: 18+

Code: NCT03175224·Phase 2·Recruiting·Listed Jun 2017

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Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

for Lung Non-Small Cell Carcinoma

Drug: Atezolizumab

Sites in Los Angeles, Beverly Hills +68 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07388524·Phase 3·Recruiting·Listed Feb 2026

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in Los Angeles, Panorama City +623 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

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A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

for Lung Non-Small Cell Carcinoma

Sites in Los Angeles +96 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07293247·Phase 2·Recruiting·Listed Dec 2025

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Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

for Lung Non-Small Cell Carcinoma

Sites in Los Angeles, Beverly Hills +270 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06498635·Phase 3·Recruiting·Listed Jul 2024

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Qualitative Study on Detection & Tx of NSCLC in Pts w/ a History of Alcohol or SUD

for Lung Non-Small Cell Carcinoma

2 locations in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT07186699·Recruiting·Listed Sep 2025

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Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for Non-small Cell Lung Cancer

Sites in Los Angeles, San Francisco +19 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT05786924·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

for Non Small Cell Lung Cancer

Drug: Osimertinib

Sites in Los Angeles, Beverly Hills & Torrance

Sponsor: Karen Reckamp, MD, MS

Sex: All·Age: 18+

Code: NCT05401110·Phase 1·Recruiting·Listed Jun 2022

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Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer

for Lung Non-Small Cell Carcinoma

Drug: Telisotuzumab Vedotin

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07323641·Phase 2·Recruiting·Listed Jan 2026

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Experiences w/ & Attitudes Towards Immune Chckpt Inhibitors in NSCLC Patients Single Center Survey Based Study

for Lung Non-Small Cell Carcinoma

2 locations in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT07339254·Recruiting·Listed Jan 2026

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Gilteritinib for the Treatment of ALK NSCLC

for Lung Non-Small Cell Carcinoma

Sites in Los Angeles +2 more locations

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT06225427·Phase 1·Recruiting·Listed Jan 2024

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A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Sites in Los Angeles +11 more locations

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07659782·Phase 2·Recruiting·Listed Jun 2026

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

Sites in Los Angeles, Duarte +46 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting·Listed Dec 2025

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Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

Sites in Los Angeles +17 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 95

Code: NCT05061550·Phase 2·Recruiting·Listed Sep 2021

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A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

for Non-small Cell Lung Cancer

Sites in Los Angeles, Santa Monica +17 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05877599·Phase 1·Recruiting·Listed May 2023

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Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

Drug: Osimertinib

Sites in Los Angeles, Santa Monica +27 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06350097·Phase 3·Recruiting·Listed Apr 2024

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

Sites in Los Angeles, Duarte +16 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting·Listed Jan 2024

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Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for Solid Tumor

Drug: INBRX-106

Sites in Los Angeles, Glendale +11 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 18+

Code: NCT04198766·Phase 1, Phase 2·Recruiting·Listed Dec 2019

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A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

for Solid Tumor, Adult

Sites in Los Angeles, San Diego +13 more locations

Sponsor: Pierre Fabre Medicament

Sex: All·Age: 18+

Code: NCT04913285·Phase 1·Recruiting·Listed Jun 2021

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