Oncology Clinical Trials in Los Angeles, CA
As of September 2026, 436 paid clinical trials are recruiting for Oncology in Los Angeles, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
Newly added in Los Angeles
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Study of TUB-040 Given With Standard Ovarian Cancer Drugs in Patients With Fast-growing Ovarian Cancer
438 clinical trials for Oncology
·Clear filters·Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
Top Research Study Locations in Los Angeles
Researchers run research studies in Los Angeles, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cedars-Sinai Medical Center | Heart Failure, Acute Myeloid Leukemia, Breast Cancer | 228 |
| Children's Hospital Los Angeles | Neuroblastoma, Acute Myeloid Leukemia, Anesthesia | 128 |
| University of California, Los Angeles | Amyotrophic Lateral Sclerosis, Depression, Focal Epilepsy | 109 |
| University of Southern California | Acute Pancreatitis, Breast Cancer, Cervical Cancer | 96 |
| UCLA / Jonsson Comprehensive Cancer Center | Prostate Carcinoma, Glioblastoma, Anatomic Stage II Breast Cancer AJCC v8 | 65 |
| University of California Los Angeles | Parkinson Disease, Bladder Cancer, Breast Cancer | 65 |
| USC / Norris Comprehensive Cancer Center | Breast Carcinoma, Clinical Stage III Gastric Cancer AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | 64 |
| Cedars Sinai Medical Center | Anxiety, Crohn's Disease, Heart Failure | 63 |
| UCLA | Bladder Cancer, Colorectal Cancer, Acute Lymphoblastic Leukemia (ALL) | 56 |
| Los Angeles General Medical Center | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 52 |
| USC Norris Comprehensive Cancer Center | Advanced Solid Tumors, Colorectal Cancer, Endometrial Cancer | 50 |
| Kaiser Permanente Los Angeles Medical Center | Intracerebral Hemorrhage, Ischemic Stroke, Stage IV Lung Cancer AJCC v8 | 42 |
| Children's Hospital of Los Angeles | Acute Lymphoblastic Leukemia, Cystic Fibrosis, Von Willebrand Disease (VWD) | 35 |
| Valkyrie Clinical Trials | Multiple Myeloma, Non-Small Cell Lung Cancer, Breast Cancer | 33 |
| Ronald Reagan UCLA Medical Center | Ischemic Stroke, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma | 24 |
| UCLA Medical Center | Colorectal Cancer, CRC, Cancer | 22 |
| USC/Norris Comprehensive Cancer Center | Breast Neoplasms, Bladder Cancer, Breast Cancer | 22 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Non-alcoholic Fatty Liver Disease, Breast Neoplasms | 16 |
| Kaiser Permanente West Los Angeles | Breast Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 16 |
| START Los Angeles | Advanced Solid Tumors, Colorectal Cancer, Endometrial Cancer | 14 |
| Cedars Sinai | 1st Line NSCLC, Advanced Solid Tumor, Aortic Valve Disease Mixed | 13 |
| David Geffen School of Medicine at UCLA | Candidemia, Candidiasis, Invasive, Developmental and Epileptic Encephalopathy | 13 |
| Keck Hospital of USC | Advanced Hepatocellular Carcinoma, Advanced or Metastatic Solid Tumors, Airway Disease | 13 |
| Keck Medicine of USC Koreatown | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 13 |
| Mattel Children's Hospital UCLA | Malignant Solid Neoplasm, Ganglioneuroblastoma, Nodular, Hematopoietic and Lymphatic System Neoplasm | 12 |
Active & Upcoming Studies in Los Angeles (2026)
Recruiting trials in Los Angeles grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (634 active studies)
- Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer · Phase 2 · Jonsson Comprehensive Cancer Center
- Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial · Phase 3 · National Cancer Institute (NCI)
Neurology & pain (110 active studies)
- The Role of Virtual Reality During Regional Anesthesia · Cedars-Sinai Medical Center
- IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success · Lucas R. Cusumano, MD
Cardiovascular (97 active studies)
Mental health & behavior (62 active studies)
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
- Group PACBT for Depression · Phase 2 · University of California, Los Angeles
Diabetes & metabolic (61 active studies)
- Screening For Social Determinants Of Health In Routine Diabetes Care · University of California, Los Angeles
- A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity · Phase 3 · Eli Lilly and Company
Pediatric (32 active studies)
- Asthma Lung Sounds With Wearable Stethoscope · Children's Hospital Los Angeles
- Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth: A Randomized Clinical Trial · Phase 3 · Children's Hospital Los Angeles
HIV / STI (23 active studies)
- Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization · Keck School of Medicine of USC
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
Eye & vision (13 active studies)
- Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension · Stanford University
- Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery · University of California, Los Angeles
Vaccines (9 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
Common conditions studied in Los Angeles
- Breast Cancer (38 active studies)
- Colorectal Cancer (31 active studies)
- Prostate Cancer (27 active studies)
- Ovarian Cancer (23 active studies)
- Cancer (22 active studies)
- Heart Failure (21 active studies)
Leading research sponsors in Los Angeles
- University of California, Los Angeles
- University of Southern California
- Cedars-Sinai Medical Center
- Jonsson Comprehensive Cancer Center
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Los Angeles?
There are approximately 1,966 recruiting clinical trials in Los Angeles, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Los Angeles pay participants?
Most recruiting trials in Los Angeles compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Los Angeles?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Los Angeles?
The most common conditions under active study in Los Angeles include Breast Cancer (38), Colorectal Cancer (31), Prostate Cancer (27), Ovarian Cancer (23), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Los Angeles?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Los Angeles on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Los Angeles?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Los Angeles?
Recruiting research sites in Los Angeles include Cedars-Sinai Medical Center, Children's Hospital Los Angeles, University of California, Los Angeles, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Los Angeles right now?
The largest active categories in Los Angeles are Cancer & tumors (634), Neurology & pain (110), Cardiovascular (97). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.