Non-small cell lung cancer (NSCLC) Clinical Trials in Los Angeles, CA
As of September 2026, 63 paid clinical trials are recruiting for Non-small cell lung cancer (NSCLC) in Los Angeles, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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64 clinical trials for Non-small cell lung cancer (NSCLC)
·Clear filters·A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
GEMINI-NSCLC: NSCLC Biomarker Study
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies
Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
A Study of NX-1607 in Adults With Advanced Malignancies
A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation
A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC
Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors
Intratumoral N17350 in Advanced Solid Tumors
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma
A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)
A Study of MGC026 in Participants With Advanced Solid Tumors
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
Top Research Study Locations in Los Angeles
Researchers run research studies in Los Angeles, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cedars-Sinai Medical Center | Heart Failure, Acute Myeloid Leukemia, Atrial Fibrillation | 236 |
| Children's Hospital Los Angeles | Neuroblastoma, Acute Myeloid Leukemia, Autism Spectrum Disorder | 129 |
| University of California, Los Angeles | Amyotrophic Lateral Sclerosis, Depression, Focal Epilepsy | 112 |
| University of Southern California | Breast Cancer, Colorectal Cancer, Head and Neck Squamous Cell Carcinoma | 100 |
| USC / Norris Comprehensive Cancer Center | Breast Carcinoma, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8 | 67 |
| UCLA / Jonsson Comprehensive Cancer Center | Prostate Carcinoma, Glioblastoma, Anatomic Stage II Breast Cancer AJCC v8 | 65 |
| University of California Los Angeles | Parkinson Disease, Bladder Cancer, Breast Cancer | 65 |
| Cedars Sinai Medical Center | Anxiety, Crohn's Disease, Heart Failure | 62 |
| UCLA | Bladder Cancer, Colorectal Cancer, Acute Lymphoblastic Leukemia (ALL) | 56 |
| USC Norris Comprehensive Cancer Center | Advanced Solid Tumors, Colorectal Cancer, Endometrial Cancer | 49 |
| Los Angeles General Medical Center | Breast Carcinoma, Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | 48 |
| Kaiser Permanente Los Angeles Medical Center | Intracerebral Hemorrhage, Ischemic Stroke, Breast Cancer | 42 |
| Children's Hospital of Los Angeles | Congenital Heart Disease (CHD), Cystic Fibrosis, Von Willebrand Disease (VWD) | 35 |
| Valkyrie Clinical Trials | Multiple Myeloma, Non-Small Cell Lung Cancer, Carcinoma, Non-Small Cell Lung | 32 |
| Ronald Reagan UCLA Medical Center | Ischemic Stroke, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma | 24 |
| UCLA Medical Center | Colorectal Cancer, CRC, Cancer | 23 |
| USC/Norris Comprehensive Cancer Center | Breast Neoplasms, Bladder Cancer, Breast Cancer | 22 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Neoplasms, Lung, Non-alcoholic Fatty Liver Disease | 17 |
| Kaiser Permanente West Los Angeles | Breast Cancer, Chronic Lymphocytic Leukemia, Adenocarcinoma of the Colon | 17 |
| Cedars Sinai | 1st Line NSCLC, Advanced Solid Tumor, Aortic Valve Disease Mixed | 14 |
| Keck Hospital of USC | Acute Kidney Injury, Advanced Hepatocellular Carcinoma, Airway Disease | 14 |
| START Los Angeles | Advanced Solid Tumors, Colorectal Cancer, Endometrial Cancer | 14 |
| David Geffen School of Medicine at UCLA | Candidemia, Candidiasis, Invasive, Diffuse Large B-cell Lymphoma (DLBCL) | 12 |
| Mattel Children's Hospital UCLA | Malignant Solid Neoplasm, Ganglioneuroblastoma, Nodular, Hematopoietic and Lymphatic System Neoplasm | 12 |
| Keck School of Medicine of USC | Acute Myeloid Leukemia, Carcinoma, Squamous Cell, Cardiovascular Diseases | 11 |
Active & Upcoming Studies in Los Angeles (2026)
Recruiting trials in Los Angeles grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (646 active studies)
- Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer · Phase 2 · Jonsson Comprehensive Cancer Center
- Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma · Phase 1 · National Cancer Institute (NCI)
Neurology & pain (112 active studies)
- The Role of Virtual Reality During Regional Anesthesia · Cedars-Sinai Medical Center
- IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success · Lucas R. Cusumano, MD
Cardiovascular (102 active studies)
Diabetes & metabolic (65 active studies)
- Screening For Social Determinants Of Health In Routine Diabetes Care · University of California, Los Angeles
- Pilot Study of Endoscopic Sleeve Gastroplasty for Obese Patients With Heart Failure and Preserved Ejection Fraction · Cedars-Sinai Medical Center
Mental health & behavior (62 active studies)
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
- Group PACBT for Depression · Phase 2 · University of California, Los Angeles
Pediatric (32 active studies)
- Reference Range Study for the Quantra System With the QPlus Cartridge in Pediatric Patients · HemoSonics LLC
- Asthma Lung Sounds With Wearable Stethoscope · Children's Hospital Los Angeles
HIV / STI (24 active studies)
- Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization · Keck School of Medicine of USC
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
Eye & vision (12 active studies)
- Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension · Stanford University
- Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery · University of California, Los Angeles
Vaccines (10 active studies)
- A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Immunocompromised Adults · Phase 3 · Pfizer
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
Common conditions studied in Los Angeles
- Breast Cancer (39 active studies)
- Colorectal Cancer (32 active studies)
- Prostate Cancer (27 active studies)
- Ovarian Cancer (24 active studies)
- Cancer (22 active studies)
- Heart Failure (21 active studies)
Leading research sponsors in Los Angeles
- University of California, Los Angeles
- University of Southern California
- Cedars-Sinai Medical Center
- Jonsson Comprehensive Cancer Center
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Los Angeles?
There are approximately 1,993 recruiting clinical trials in Los Angeles, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Los Angeles pay participants?
Most recruiting trials in Los Angeles compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Los Angeles?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Los Angeles?
The most common conditions under active study in Los Angeles include Breast Cancer (39), Colorectal Cancer (32), Prostate Cancer (27), Ovarian Cancer (24), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Los Angeles?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Los Angeles on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Los Angeles?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Los Angeles?
Recruiting research sites in Los Angeles include Cedars-Sinai Medical Center, Children's Hospital Los Angeles, University of California, Los Angeles, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Los Angeles right now?
The largest active categories in Los Angeles are Cancer & tumors (646), Neurology & pain (112), Cardiovascular (102). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.