Clinical Trials at University of Southern California

As of July 2026, 84 paid clinical trials are recruiting at University of Southern California, located at 1441 EASTLAKE AVE, LOS ANGELES, CA 90089-0112, phone (323) 865-3000 in Los Angeles, California. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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84 clinical trials at University of Southern California

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HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

81 locations incl. Phoenix

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting

Apply to this trial

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

44 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

42 locations incl. Birmingham

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting

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MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

for Femoral Neck Fractures

13 locations incl. Irvine

Sponsor: University of Southern California

Sex: All·Age: 60+

Code: NCT07244211·Recruiting

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DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

for High Grade Glioma

5 locations incl. Los Angeles

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06504381·Phase 1, Phase 2·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

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Transformative Research in Diabetic Nephropathy

for Diabetic Nephropathies

17 locations incl. Little Rock

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 100

Code: NCT02986984·Recruiting

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National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

18 locations incl. Los Angeles

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT05197920·Recruiting

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Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

for Osteonecrosis of the Femoral Head

10 locations incl. Los Angeles

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT06123481·Recruiting

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Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis

for Recurrent Acute Pancreatitis

5 locations incl. Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18 - 75

Code: NCT05771675·EARLY_Phase 1·Recruiting

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Modernizing Perinatal Syphilis Testing

for Syphilis

9 locations incl. Los Angeles

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: Up to 45

Code: NCT06082453·Recruiting

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DFC 004 Biomarkers for Active Diabetic Foot Ulcers

for Diabetic Foot Ulcer

8 locations incl. Tucson

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06104969·Recruiting

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DILIN - Prospective Study

for Liver Diseases

6 locations incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00345930·Recruiting

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Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

for Neuromyelitis Optica

10 locations incl. Los Angeles

Sponsor: Ad scientiam

Sex: All·Age: 18+

Code: NCT05566769·Recruiting

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Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients

for Fracture Lower Leg

3 locations incl. Los Angeles

Sponsor: Texas Tech University Health Sciences Center, El Paso

Sex: All·Age: 18+

Code: NCT07561541·Phase 4·Recruiting

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Empowering Youth With School Discipline Referrals as Peer Coaches

for Disruptive Behavior

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 10 - 15

Code: NCT07515742·Recruiting

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New Approach to Objectively Measure Social Engagement in Older Adults With Hearing Loss

for Hearing Loss, Bilateral (Causes Other Than Tumors)

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06781749·Recruiting

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Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety

for Generalized Anxiety Disorder (GAD)

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT07430800·Recruiting

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FEAST Perinatal Support Program Intervention

for Diet, Healthy

1 location in Los Angeles

Sponsor: University of Southern California

Sex: Female·Age: 18+

Code: NCT06715787·Recruiting

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Digital vs. Parent Modeled Toothbrushing

for Plaque Reduction

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 3 - 6·Accepts healthy volunteers

Code: NCT07441148·Recruiting

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Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.

for Caregiver Burden

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06418971·Recruiting

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Cardiac-Control Affecting Learning Through Mindfulness (CALM)

for Age-related Cognitive Decline

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 50 - 70·Accepts healthy volunteers

Code: NCT06410157·Recruiting

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Abuse Liability and Appeal of Oral Nicotine Products

for Nicotine Dependence

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 21 - 25·Accepts healthy volunteers

Code: NCT06506162·Recruiting

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Regulation of Affect and Physiology in Depression

for Major Depressive Disorder

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18 - 27·Accepts healthy volunteers

Code: NCT06345859·Phase 2·Recruiting

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Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

for Exocrine Pancreatic Insufficiency

6 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06477159·Phase 4·Recruiting

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Demonstrating the Efficacy of a Spanish-Language Program for Latino Dementia Caregivers

for Caregiver Burden of People With Dementia

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06747637·Recruiting

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Social Facilitation of Alcohol Effects and Alcohol Misuse in Young Adults

for Alcohol Consumption

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 21 - 28·Accepts healthy volunteers

Code: NCT06627803·Recruiting

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Personalized Health Self-Management Training for Colorectal Cancer Survivors

for Colorectal Cancer

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT05984589·Recruiting

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Characterization and Treatment of Adolescent Depression

for Depression

3 locations incl. Los Angeles

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 11 - 25·Accepts healthy volunteers

Code: NCT03388606·Recruiting

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Cefixime Clinical Trial

for Syphilis

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT04958122·Phase 3·Recruiting

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Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States

for No Condition

2 locations incl. Downey

Sponsor: University of Southern California

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07110688·Recruiting

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eMOTION: Examining Affective Mechanisms in Physical Activity Engagement

for Physical Inactivity

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06570642·Recruiting

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iMmune SignAtures and Clinical outComes in AP

for Acute Pancreatitis

5 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18 - 75

Code: NCT05878236·Recruiting

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Feasibility of an In-home Standing and Walking Intervention for Infants With and at High Risk of Cerebral Palsy

for Cerebral Palsy

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 5 Months - 2

Code: NCT05781438·Recruiting

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Sensory Motor Transformations in Human Cortex

for Quadriplegia

4 locations incl. Downey

Sponsor: Richard A. Andersen, PhD

Sex: All·Age: 22 - 65

Code: NCT01964261·Recruiting

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Epilepsy Learning Healthcare System (ELHS)

for Epilepsy

13 locations incl. Phoenix

Sponsor: Epilepsy Foundation of America

Sex: All·Age: All ages

Code: NCT06265103·Recruiting

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Adapting Lifestyle Offloading for DFUs

for Diabetic Foot Ulcer

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 21+

Code: NCT06278935·Recruiting

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Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery

for Delayed Onset Muscle Soreness

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT06815367·Recruiting

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Effects of Nicotine Pouch Characteristics on Perceptions and Behavior

for Nicotine Pouch Self-Administration

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 21 - 35·Accepts healthy volunteers

Code: NCT06597435·Recruiting

Apply to this trial