Clinical Trials at University of Southern California

As of August 2026, 76 paid clinical trials are recruiting at University of Southern California, located at 1441 EASTLAKE AVE, LOS ANGELES, CA 90089-0112, phone (323) 865-3000 in Los Angeles, California. Active studies at this site cover conditions such as Breast Cancer, Colorectal Cancer and Prostate Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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Healthy volunteers only

Newly added in Los Angeles

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

Stiffness and Low Dose Irradiation RCT

for Arthrofibrosis of Knee

Sites in Los Angeles +1 more location

Sponsor: Mount Sinai Hospital, Canada

Sex: All·Age: 18+

Code: NCT07767097·Recruiting·Listed Aug 17, 2026

Apply to this trial

Stroke Volume-based Fluid Resuscitation in AP

for Acute Pancreatitis (AP)

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18 - 75

Code: NCT07756476·Recruiting·Listed Aug 10, 2026

Apply to this trial

Social Media Influences on Engagement and Susceptibility to Non-combustible Tobacco Product Use Among Youth and Young Adults (AYA)

for Perceptions of Tobacco Products

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 14 - 17·Accepts healthy volunteers

Code: NCT07721883·Recruiting·Listed Jul 23, 2026

Apply to this trial

79 clinical trials at University of Southern California

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A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for Colorectal Neoplasms

Sites in Los Angeles, Van Nuys +106 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05253651·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

Sites in Los Angeles, Whittier +30 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting·Listed Aug 2024

Apply to this trial

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

for Moderately to Severely Active Ulcerative Colitis

Drug: Afimkibart

Sites in Los Angeles, Garden Grove +68 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06588855·Phase 3·Recruiting·Listed Sep 2024

Apply to this trial

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

for Chronic Graft-versus-host-disease

Sites in Los Angeles, Duarte +34 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06585774·Phase 3·Recruiting·Listed Sep 2024

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A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for Myelofibrosis

Sites in Los Angeles, Duarte +28 more locations

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT04176198·Phase 1, Phase 2·Recruiting·Listed Nov 2019

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

Sites in Los Angeles +25 more locations

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting·Listed Apr 2025

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A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)

for Generalized Myasthenia Gravis

Drug: Telitacicept

Sites in Los Angeles, Orange +24 more locations

Sponsor: Vor Biopharma

Sex: All·Age: 18+

Code: NCT06456580·Phase 3·Recruiting·Listed Jun 2024

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Zenith® Fenestrated+ Clinical Study

for Aortic Aneurysm, Abdominal

Sites in Los Angeles, La Jolla +28 more locations

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT04875429·Recruiting·Listed May 2021

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

Sites in Los Angeles, Santa Monica +30 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting·Listed Oct 2024

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Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis

for AAA - Abdominal Aortic Aneurysm

Sites in Los Angeles, Irvine +54 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06218875·Recruiting·Listed Jan 2024

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Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for Type 2 Diabetes Mellitus

Sites in Los Angeles, Santa Barbara +9 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 14 - 75

Code: NCT07579702·Recruiting·Listed May 2026

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Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

for Type 2 Diabetes Mellitus

Sites in Los Angeles, Newport Beach +24 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 18 - 75

Code: NCT07521475·Recruiting·Listed Apr 2026

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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

for Vascular Disease

Sites in Los Angeles, Stanford +22 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06658730·Recruiting·Listed Oct 2024

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Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA

for Aortic Arch Aneurysm

Sites in Los Angeles +20 more locations

Sponsor: Artivion Inc.

Sex: All·Age: 18 - 80

Code: NCT07089576·Recruiting·Listed Jul 2025

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GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

for Aortic Dissection

Sites in Los Angeles, Palo Alto +20 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06827990·Recruiting·Listed Feb 2025

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A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Los Angeles, San Diego +17 more locations

Sponsor: Rein Therapeutics

Sex: All·Age: 40+

Code: NCT06968845·Phase 2·Recruiting·Listed May 2025

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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for Solid Tumors With HRAS Alterations

Sites in Los Angeles +21 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06026410·Phase 1·Recruiting·Listed Sep 2023

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Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities

for Periprosthetic Joint Infections

Sites in Los Angeles +12 more locations

Sponsor: Elute, Inc.

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT05361941·Recruiting·Listed May 2022

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A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

for Advanced or Metastatic Colorectal Cancer

Drug: Amivantamab

Sites in Los Angeles +6 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05379595·Phase 1, Phase 2·Recruiting·Listed May 2022

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Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

for Ovarian Cancer

Sites in Los Angeles, Newport +8 more locations

Sponsor: Nammi Therapeutics Inc

Sex: All·Age: 18+

Code: NCT06582017·Phase 1·Recruiting·Listed Sep 2024

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Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

for T-cell Lymphoma

Sites in Los Angeles, Duarte +8 more locations

Sponsor: SciTech Development, Inc.

Sex: All·Age: 18+

Code: NCT04234048·Phase 1·Recruiting·Listed Jan 2020

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A Study of NX-1607 in Adults With Advanced Malignancies

for Ovarian Cancer, Epithelial

Sites in Los Angeles, San Francisco +7 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05107674·Phase 1·Recruiting·Listed Nov 2021

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A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

for Endometrial Cancer

Drug: Lifileucel

Sites in Los Angeles +11 more locations

Sponsor: Iovance Biotherapeutics, Inc.

Sex: Female·Age: 18 - 70

Code: NCT06481592·Phase 2·Recruiting·Listed Jul 2024

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A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

for Advanced Solid Tumor

Sites in Los Angeles, Newport Beach +11 more locations

Sponsor: Volastra Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05902988·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer

for FIGO Stage III and IV Ovarian Cancer

Sites in Los Angeles, Fullerton +5 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18 - 75

Code: NCT07322094·Phase 1, Phase 2·Recruiting·Listed Jan 2026

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Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for Diffuse Astrocytoma, IDH-Mutant

Sites in Los Angeles, Beverly Hills +5 more locations

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06047379·Phase 1, Phase 2·Recruiting·Listed Sep 2023

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A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP)

for Chronic Primary Immune Thrombocytopenia (ITP)

Sites in Los Angeles +2 more locations

Sponsor: Kedrion S.p.A.

Sex: All·Age: 18 - 70

Code: NCT07059000·Phase 3·Recruiting·Listed Jul 2025

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NEO100 and High-Grade Meningioma

for Residual, Progressive or Recurrent Grade II or III Meningioma

Sites in Los Angeles, Santa Monica +3 more locations

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 12+

Code: NCT05023018·Phase 2·Recruiting·Listed Aug 2021

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Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Los Angeles +1 more location

Sponsor: SciTech Development, Inc.

Sex: All·Age: 18+

Code: NCT06922539·Phase 1·Recruiting·Listed Apr 2025

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Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

for Cystic Fibrosis

Sites in Los Angeles +2 more locations

Sponsor: SpliSense Ltd.

Sex: All·Age: 18+

Code: NCT06429176·Phase 2·Recruiting·Listed May 2024

Apply to this trial

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma (HNSCC)

Sites in Los Angeles +3 more locations

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT06943521·Phase 1, Phase 2·Recruiting·Listed Apr 2025

Apply to this trial

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

for Amyotrophic Lateral Sclerosis

Drug: Masitinib

Sites in Los Angeles +5 more locations

Sponsor: AB Science

Sex: All·Age: 18 - 81

Code: NCT03127267·Phase 3·Recruiting·Listed Apr 2017

Apply to this trial

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

for Advanced Cancer

Sites in Los Angeles +6 more locations

Sponsor: Qurient Co., Ltd.

Sex: All·Age: 18+

Code: NCT05394103·Phase 1, Phase 2·Recruiting·Listed May 2022

Apply to this trial

Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients

for Fracture Lower Leg

Sites in Los Angeles +2 more locations

Sponsor: Texas Tech University Health Sciences Center, El Paso

Sex: All·Age: 18+

Code: NCT07561541·Phase 4·Recruiting·Listed May 2026

Apply to this trial

Empowering Youth With School Discipline Referrals as Peer Coaches

for Disruptive Behavior

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 10 - 15

Code: NCT07515742·Recruiting·Listed Apr 2026

Apply to this trial

Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety

for Generalized Anxiety Disorder (GAD)

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT07430800·Recruiting·Listed Feb 2026

Apply to this trial

MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

for Femoral Neck Fractures

Sites in Los Angeles, Irvine +18 more locations

Sponsor: University of Southern California

Sex: All·Age: 60+

Code: NCT07244211·Recruiting·Listed Nov 2025

Apply to this trial

Digital vs. Parent Modeled Toothbrushing

for Plaque Reduction

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 3 - 6·Accepts healthy volunteers

Code: NCT07441148·Recruiting·Listed Feb 2026

Apply to this trial

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

Sites in Los Angeles, Stanford +37 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting·Listed Aug 2013

Apply to this trial

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for Open tíbia Fracture

Sites in Los Angeles, Orange +25 more locations

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05615844·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial

Common conditions studied in Los Angeles

Breast Cancer (38 active studies)
Colorectal Cancer (31 active studies)
Prostate Cancer (27 active studies)
Ovarian Cancer (23 active studies)
Cancer (22 active studies)
Heart Failure (21 active studies)

Leading research sponsors in Los Angeles

University of California, Los Angeles
University of Southern California
Cedars-Sinai Medical Center
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Frequently asked questions

How many paid clinical trials are currently recruiting in Los Angeles?

There are approximately 1,968 recruiting clinical trials in Los Angeles, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Los Angeles pay participants?

Most recruiting trials in Los Angeles compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Los Angeles?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Los Angeles?

The most common conditions under active study in Los Angeles include Breast Cancer (38), Colorectal Cancer (31), Prostate Cancer (27), Ovarian Cancer (23), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Los Angeles?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Los Angeles on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Los Angeles?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Los Angeles?

Recruiting research sites in Los Angeles include Cedars-Sinai Medical Center, Children's Hospital Los Angeles, University of California, Los Angeles, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Los Angeles right now?

The largest active categories in Los Angeles are Cancer & tumors (637), Neurology & pain (111), Cardiovascular (96). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

What is the address of University of Southern California?

University of Southern California is located at 1441 EASTLAKE AVE, LOS ANGELES, CA 90089-0112. Use the Google Maps link in the intro above to get directions.

How do I contact University of Southern California?

You can reach University of Southern California by phone at (323) 865-3000. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.

Browse more clinical trials

Other cities in California

San Francisco, CA(1,349)San Diego, CA(758)Palo Alto, CA(652)Sacramento, CA(589)Duarte, CA(543)La Jolla, CA(532)Orange, CA(508)Stanford, CA(426)Irvine, CA(375)Long Beach, CA(204)Newport Beach, CA(186)Santa Monica, CA(185)Walnut Creek, CA(184)Oakland, CA(170)Beverly Hills, CA(169)Torrance, CA(164)Loma Linda, CA(161)Anaheim, CA(126)Santa Rosa, CA(108)Fresno, CA(106)Pasadena, CA(103)Fountain Valley, CA(97)Fullerton, CA(96)Redwood City, CA(96)Glendale, CA(94)Lancaster, CA(87)Riverside, CA(85)Fremont, CA(81)Los Alamitos, CA(78)Huntington Beach, CA(77)San Jose, CA(77)Roseville, CA(71)Santa Barbara, CA(70)Vallejo, CA(66)Modesto, CA(64)Bakersfield, CA(63)Thousand Oaks, CA(62)Northridge, CA(58)Upland, CA(58)Chula Vista, CA(57)Burbank, CA(56)Berkeley, CA(55)Oceanside, CA(51)Garden Grove, CA(49)Santa Ana, CA(49)Stockton, CA(48)Santa Clara, CA(47)Pomona, CA(46)Bellflower, CA(43)San Leandro, CA(43)Santa Maria, CA(43)Tarzana, CA(42)Davis, CA(41)Downey, CA(41)San Luis Obispo, CA(41)Arroyo Grande, CA(40)Oxnard, CA(40)San Rafael, CA(40)La Mesa, CA(38)West Hills, CA(37)

Related healthcare resources in California

Latest Los Angeles, CA clinical trials research report

Trials by condition in Los Angeles

Breast Cancer· 38 Colorectal Cancer· 31 Prostate Cancer· 27 Ovarian Cancer· 23 Heart Failure· 21 Endometrial Cancer· 20