Oncology Clinical Trials in Madison, WI
As of August 2026, 139 paid clinical trials are recruiting for Oncology in Madison, Wisconsin. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Madison
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Targeting Aurora A Kinase to Overcome Treatment Resistance in Advanced HR+/HER2+ Breast Cancer
141 clinical trials for Oncology
·Clear filters·A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study of ASP3082 in Adults With Advanced Solid Tumors
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)
Study of ORIC-944 in Patients With Metastatic Prostate Cancer
Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
Top Research Study Locations in Madison
Researchers run research studies in Madison, WI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Wisconsin | Cystic Fibrosis, Alzheimer Disease, Healthy | 114 |
| University of Wisconsin Carbone Cancer Center - University Hospital | Acute Myeloid Leukemia, Metastatic Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 89 |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center | Metastatic Malignant Solid Neoplasm, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 61 |
| University of Wisconsin - Madison | Gastroschisis, Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL) | 39 |
| University of Wisconsin Carbone Cancer Center | Prostate Cancer, Acute Myeloid Leukemia, Breast Cancer | 31 |
| University of Wisconsin-Madison | Achondroplasia, Acute Respiratory Failure, Acute Sinusitis | 21 |
| William S. Middleton Memorial Veterans Hospital, Madison, WI | Metastatic Prostate Cancer, Aging, Alcohol Use Disorder | 15 |
| William S Middleton VA Medical Center | Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia, Myelodysplastic Syndrome | 13 |
| UW School of Medicine and Public Health | Diabetic Retinopathy, Aphasia, Diabetes Mellitus | 12 |
| UW Carbone Cancer Center | Breast Cancer, Metastatic Cancer, Advanced Breast Cancer | 8 |
| University of Wisconsin Hospital and Clinics | Pulmonary Hypertension, AML With Mutated NPM1, Acute Myeloid Leukemia | 8 |
| UW Hospital and Clinics | Cytomegalovirus Infections, Diabetic Retinopathy, High-need, High-complexity | 7 |
| University of Wisconsin Madison | Asthma, Alzheimer's Disease, Asthma Chronic | 7 |
| American Family Children's Hospital | Cardiac Arrest, Out-Of-Hospital, Hospitalized Child, Hypothermia, Induced | 6 |
| University of Wisconsin School of Medicine and Public Health | Breast Cancer, Genetic Disease, HER2-negative Breast Cancer | 5 |
| UW Health | ACL, Communication, G12D Mutated KRAS | 4 |
| UW Health University Hospital | Consciousness Disorders, Fracture Fixation, Idiopathic Pulmonary Fibrosis | 4 |
| University Hospital and UW Health Clinics | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, Achondroplasia | 4 |
| University of Wisconsin - Carbone Cancer Center | Breast Neoplasms, Cholangiocarcinoma, Colorectal Cancer | 4 |
| University of Wisconsin Clinical Science Center | Cervical Cancer, Leukemia, Leukemia, Myeloid | 4 |
| University of Wisconsin Madison - Waisman Center Bone Dysplasia Clinic | Hypochondroplasia, Achondroplasia | 4 |
| University of Wisconsin, Madison | Atrial Arrhythmia, Atrial Tachycardia, CLOVES Syndrome | 4 |
| Center for Healthy Minds | Asthma, Depression, Anxiety, Well-Being, Psychological | 3 |
| Meriter Hospital | Aging, Alzheimer Disease, Caregiver Burden | 3 |
| University Hospital | Acute Treatment of Migraine, Opiate Use Disorder, Opiate-Related Disorders | 3 |
Active & Upcoming Studies in Madison (2026)
Recruiting trials in Madison grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (204 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
Cardiovascular (27 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA) · VA Office of Research and Development
Neurology & pain (23 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Lily's Grace Temporal Interference · University of Wisconsin, Madison
Mental health & behavior (18 active studies)
- The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study · University of Wisconsin, Madison
- Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls · University of Wisconsin, Madison
Pediatric (12 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- Testing and Evaluating an Interactive Media Use Journal for Adolescents · University of Wisconsin, Madison
Diabetes & metabolic (10 active studies)
- Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome · EARLY_Phase 1 · University of Wisconsin, Madison
- Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes · University of Wisconsin, Madison
Eye & vision (3 active studies)
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
- Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID) · University of Wisconsin, Madison
Common conditions studied in Madison
- Prostate Cancer (13 active studies)
- Acute Myeloid Leukemia (12 active studies)
- Breast Cancer (11 active studies)
- Colorectal Cancer (7 active studies)
- Achondroplasia (6 active studies)
- Advanced Solid Tumor (6 active studies)
Leading research sponsors in Madison
- University of Wisconsin, Madison
- National Cancer Institute (NCI)
- Children's Oncology Group
- VA Office of Research and Development
- Merck Sharp & Dohme LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Madison?
There are approximately 565 recruiting clinical trials in Madison, Wisconsin listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Madison pay participants?
Most recruiting trials in Madison compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Madison?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Madison?
The most common conditions under active study in Madison include Prostate Cancer (13), Acute Myeloid Leukemia (12), Breast Cancer (11), Colorectal Cancer (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Madison?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Madison on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Madison?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Madison?
Recruiting research sites in Madison include University of Wisconsin, University of Wisconsin Carbone Cancer Center - University Hospital, University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Madison right now?
The largest active categories in Madison are Cancer & tumors (204), Cardiovascular (27), Neurology & pain (23). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.