Oncology Clinical Trials in Madison, WI
As of July 2026, 131 paid clinical trials are recruiting for Oncology in Madison, Wisconsin. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Madison
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Maximizing Quality of Life After Cancer Through Rehabilitation
Chemical-Shift-Encoded MRI for Active Bone Marrow Dosimetry in Radiopharmaceutical Therapy
134 clinical trials for Oncology
·Clear filters·↓ Download CSVA Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
Study of ORIC-944 in Patients With Metastatic Prostate Cancer
A Study of ASP3082 in Adults With Advanced Solid Tumors
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
About research studies in Madison
Madison has approximately 548 recruiting research studies across a wide range of therapeutic areas. Wisconsin hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Madison
Researchers run research studies in Madison, WI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Wisconsin | Cystic Fibrosis, Alzheimer Disease, Healthy | 111 |
| University of Wisconsin Carbone Cancer Center - University Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm | 88 |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Metastatic Malignant Solid Neoplasm | 57 |
| University of Wisconsin - Madison | Gastroschisis, Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL) | 37 |
| University of Wisconsin Carbone Cancer Center | Prostate Cancer, Acute Myeloid Leukemia, Breast Cancer | 29 |
| University of Wisconsin-Madison | Achondroplasia, Acute Respiratory Failure, Acute Sinusitis | 20 |
| William S Middleton VA Medical Center | Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia, Myelodysplastic Syndrome | 13 |
| UW School of Medicine and Public Health | Diabetic Retinopathy, Aphasia, Diabetes Mellitus | 12 |
| William S. Middleton Memorial Veterans Hospital, Madison, WI | Metastatic Prostate Cancer, Aging, Asymptomatic Bacteriuria | 12 |
| UW Carbone Cancer Center | Breast Cancer, Metastatic Cancer, Advanced Breast Cancer | 8 |
| University of Wisconsin Hospital and Clinics | Pulmonary Hypertension, AML With Mutated NPM1, Acute Myeloid Leukemia | 8 |
| UW Hospital and Clinics | Cytomegalovirus Infections, Diabetic Retinopathy, High-need, High-complexity | 7 |
| University of Wisconsin Madison | Asthma, Alzheimer's Disease, Asthma Chronic | 7 |
| American Family Children's Hospital | Cardiac Arrest, Out-Of-Hospital, Hospitalized Child, Hypothermia, Induced | 6 |
| University of Wisconsin School of Medicine and Public Health | Breast Cancer, Genetic Disease, HER2-negative Breast Cancer | 6 |
| UW Health University Hospital | Consciousness Disorders, Fracture Fixation, Idiopathic Pulmonary Fibrosis | 4 |
| University Hospital and UW Health Clinics | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, Achondroplasia | 4 |
| University of Wisconsin - Carbone Cancer Center | Breast Neoplasms, Cholangiocarcinoma, Colorectal Cancer | 4 |
| University of Wisconsin Clinical Science Center | Cervical Cancer, Leukemia, Leukemia, Myeloid | 4 |
| University of Wisconsin Madison - Waisman Center Bone Dysplasia Clinic | Hypochondroplasia, Achondroplasia | 4 |
| University of Wisconsin, Madison | Atrial Arrhythmia, Atrial Tachycardia, CLOVES Syndrome | 4 |
| Center for Healthy Minds | Asthma, Depression, Anxiety, Well-Being, Psychological | 3 |
| Fortrea Clinical Research Unit Inc. | Healthy, Healthy Male Volunteers, Healthy Volunteers | 3 |
| Meriter Hospital | Aging, Alzheimer Disease, Caregiver Burden | 3 |
| UW Health | ACL, Communication, Oncology | 3 |
Active & Upcoming Studies in Madison (2026)
Recruiting trials in Madison grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (197 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- Targeting Aurora A Kinase to Overcome Treatment Resistance in Advanced HR+/HER2+ Breast Cancer · Phase 2 · University of Wisconsin, Madison
Cardiovascular (25 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- Randomized Trial of SGLT2i in Heart Transplant Recipients · Phase 4 · VA Office of Research and Development
Neurology & pain (24 active studies)
- The Gut - PRO Study · Phase 2 · University of Wisconsin, Madison
- Lily's Grace Temporal Interference · University of Wisconsin, Madison
Mental health & behavior (18 active studies)
- Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls · University of Wisconsin, Madison
- Music Interventions During Wide-Awake Hand Surgery · University of Wisconsin, Madison
Pediatric (13 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- Testing and Evaluating an Interactive Media Use Journal for Adolescents · University of Wisconsin, Madison
Diabetes & metabolic (12 active studies)
- Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes · University of Wisconsin, Madison
- Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome · EARLY_Phase 1 · University of Wisconsin, Madison
Eye & vision (3 active studies)
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
- Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID) · University of Wisconsin, Madison
Vaccines (1 active study)
Common conditions studied in Madison
- Prostate Cancer (12 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Breast Cancer (11 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Acute Myeloid Leukemia (10 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Healthy (8 active studies). Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials.
- Achondroplasia (6 active studies). Recruiting Achondroplasia studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumor (6 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Madison
- University of Wisconsin, Madison
- National Cancer Institute (NCI)
- Children's Oncology Group
- Merck Sharp & Dohme LLC
- VA Office of Research and Development
Local regulations and guidelines
Clinical trials in Wisconsin are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Wisconsin research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Madison. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Madison
Hipa.ai aggregates every recruiting study in Madison from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Madison?
There are approximately 548 recruiting clinical trials in Madison, Wisconsin listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Madison pay participants?
Most recruiting trials in Madison compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Madison?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Madison?
The most common conditions under active study in Madison include Prostate Cancer (12), Breast Cancer (11), Acute Myeloid Leukemia (10), Healthy (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Madison?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Madison on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Madison?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Madison?
Recruiting research sites in Madison include University of Wisconsin, University of Wisconsin Carbone Cancer Center - University Hospital, University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Madison right now?
The largest active categories in Madison are Cancer & tumors (197), Cardiovascular (25), Neurology & pain (24). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.