Clinical Trials at St. Jude Children's Research Hospital

As of July 2026, 114 paid clinical trials are recruiting at St. Jude Children's Research Hospital, located at 262 DANNY THOMAS PL, MEMPHIS, TN 38105-3678, phone (901) 595-2911 in Memphis, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 10, 2026.

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114 clinical trials at St. Jude Children's Research Hospital

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Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 8+·Accepts healthy volunteers

Code: NCT05810181·Recruiting

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Long-term Follow-up After Adoptive Transfer of Genetically Modified Cell Products

for Relapsed Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT05713214·Recruiting

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Response to Influenza Vaccination in Pediatric Oncology Patients

for Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 18

Code: NCT05384288·Recruiting

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Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

for Refractory Solid Tumor

Drug: Atezolizumab

2 locations incl. Germantown

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT05468359·Phase 1, Phase 2·Recruiting

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Childhood Cancer Survivors' Affective Response to Exercise

for ALL, Childhood

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18 - 39

Code: NCT05763290·Recruiting

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The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network

for Knowledge, Attitudes, Practice

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT05454618·Recruiting

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Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

for Acute Pancreatitis

3 locations incl. Charlotte

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04195347·Phase 1, Phase 2·Recruiting

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Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

for Glioma

2 locations incl. Rochester

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 6 - 21

Code: NCT04065776·Recruiting

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Protocol For Collecting Data On Patients With Childhood Cancer

for Childhood Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT00684580·Recruiting

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Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer

for Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 5+

Code: NCT00760656·Recruiting

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Sickle Cell Clinical Research and Intervention Program

for Sickle Cell Disease

6 locations incl. Peoria

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT02098863·Recruiting

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Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients

for Solid, Liquid, Central Nervous System Tumors

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT02530658·Recruiting

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Investigation of the Genetics of Hematologic Diseases

for Bone Marrow Failure Syndromes

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT02720679·Recruiting

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Familial Investigations of Childhood Cancer Predisposition

for Acute Leukemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT03050268·Recruiting

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B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

for Pediatric Solid Tumor

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04897321·Phase 1·Recruiting

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CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

for AML/MDS

2 locations incl. Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04318678·Phase 1·Recruiting

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Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

for Sickle Cell Disease

2 locations incl. Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 6 - 25

Code: NCT03353584·Recruiting

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Discarded Bone Marrow for Hematology Research

for Hemoglobinopathies

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04671212·Recruiting

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Study Of Cold Cap Therapy For Prevention of Hairloss in Pediatric Patients Receiving Chemotherapy For Non-Malignant Indications and Solid Tumors

for Alopecia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 7+

Code: NCT04764357·Recruiting

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Indocyanine Green (ICG) Guided Tumor Resection

for Neoplastic Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04084067·Phase 1·Recruiting

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Pharmacogenetic Determinants Of Treatment Response In Children

for All Malignancies

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT00730678·Recruiting

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Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

for Normal and Diseased Tissue and Body Fluids Samples

14 locations incl. Huntsville

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01354002·Recruiting

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Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

for Differentiated Thyroid Cancer

5 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 99

Code: NCT05783323·Phase 2·Recruiting

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Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

for Medulloblastoma

10 locations incl. Palo Alto

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 59 Months

Code: NCT05535166·Phase 2·Recruiting

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SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

for Low-Grade Glioma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 2 - 24

Code: NCT04923126·Phase 1, Phase 2·Recruiting

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Molecular Analysis Of Solid Tumors

for Pediatric Solid Tumors

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 25

Code: NCT01050296·Recruiting

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Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

for Melanoma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 18

Code: NCT02775643·Recruiting

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Childhood Cancer Predisposition Study (CCPS)

for Pediatric Cancer

6 locations incl. Atlanta

Sponsor: Emory University

Sex: All·Age: All ages

Code: NCT04511806·Recruiting

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Haploidentical HCT for Severe Aplastic Anemia

for Aplastic Anemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04558736·Phase 2·Recruiting

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Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma

for Childhood Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+

Code: NCT06747910·Recruiting

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Writing Intervention With Adolescents and Young Adults With Cancer

for Cancer Patients

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 15 - 25

Code: NCT05975333·Recruiting

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Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT04416178·Recruiting

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Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

3 locations incl. Duarte

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting

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Bereaved Parent Conversations on Hope

for Hope

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07675083·Recruiting·Listed Jun 30, 2026

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