Clinical Trials at St. Jude Children's Research Hospital

As of September 2026, 115 paid clinical trials are recruiting at St. Jude Children's Research Hospital, located at 262 DANNY THOMAS PL, MEMPHIS, TN 38105-3678, phone (901) 595-2911 in Memphis, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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117 clinical trials at St. Jude Children's Research Hospital

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Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

for High Grade Glioma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 3

Code: NCT06528691·Phase 2·Recruiting·Listed Jul 2024

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Retinoblastoma Patient Clinical Database and Tissue Repository

for Retinoblastoma

Sites in Memphis +7 more locations

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 0 - 18

Code: NCT04959097·Recruiting·Listed Jul 2021

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Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18 - 21·Accepts healthy volunteers

Code: NCT05583721·Phase 2·Recruiting·Listed Oct 2022

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Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

for Solid Tumor

Sites in Memphis +2 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 20

Code: NCT05645523·EARLY_Phase 1·Recruiting·Listed Dec 2022

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CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions

for B-Cell Acute Lymphoblastic Leukemia (B-ALL)

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT07048535·Recruiting·Listed Jul 2025

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Gene Editing For Sickle Cell Disease

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18 - 24

Code: NCT06506461·Phase 1·Recruiting·Listed Jul 2024

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Discarded Bone Marrow for Hematology Research

for Hemoglobinopathies

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04671212·Recruiting·Listed Dec 2020

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Study Of Cold Cap Therapy For Prevention of Hairloss in Pediatric Patients Receiving Chemotherapy For Non-Malignant Indications and Solid Tumors

for Alopecia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 7+

Code: NCT04764357·Recruiting·Listed Feb 2021

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Pharmacogenetic Determinants Of Treatment Response In Children

for All Malignancies

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT00730678·Recruiting·Listed Aug 2008

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Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

for Normal and Diseased Tissue and Body Fluids Samples

Sites in Memphis, Johnson City +11 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01354002·Recruiting·Listed May 2011

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School Readiness Intervention for Preschool Children With Sickle Cell Disease

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 42 Months - 78 Months

Code: NCT06367192·Recruiting·Listed Apr 2024

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Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition

for Genetic Predisposition

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 10 - 24

Code: NCT05849155·Recruiting·Listed May 2023

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Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas

for Sarcoma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT07222735·Phase 1·Recruiting·Listed Oct 2025

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Neuroblastoma Biology Study

for Neuroblastoma

Sites in Memphis +13 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting·Listed Apr 2012

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CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia

for Acute Lymphoblastic Leukemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT06847269·Phase 2·Recruiting·Listed Feb 2025

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Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for Papillary Thyroid Cancer

Sites in Memphis +7 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0+

Code: NCT05024929·Recruiting·Listed Aug 2021

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CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

for Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT06326463·Phase 1·Recruiting·Listed Mar 2024

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Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

for Charcot-Marie-Tooth Disease, Type Ia (Disorder)

Sites in Memphis +16 more locations

Sponsor: University of Iowa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193088·Recruiting·Listed Sep 2010

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Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

for Melanoma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 18

Code: NCT02775643·Recruiting·Listed May 2016

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Childhood Cancer Predisposition Study (CCPS)

for Pediatric Cancer

Sites in Memphis +5 more locations

Sponsor: Emory University

Sex: All·Age: All ages

Code: NCT04511806·Recruiting·Listed Aug 2020

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Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

for Relapsed/Refractory KMT2A-r Acute Leukemia

Sites in Memphis +10 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 0 - 21

Code: NCT06376162·Phase 1·Recruiting·Listed Apr 2024

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Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

for Charcot Marie Tooth Disease

Sites in Memphis +17 more locations

Sponsor: Michael Shy

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193075·Recruiting·Listed Sep 2010

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Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

Sites in Memphis +26 more locations

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting·Listed Sep 2022

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Writing Intervention With Adolescents and Young Adults With Cancer

for Cancer Patients

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 15 - 25

Code: NCT05975333·Recruiting·Listed Aug 2023

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Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT04416178·Recruiting·Listed Jun 2020

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Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

Sites in Memphis +2 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting·Listed Jan 2022

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Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

for Differentiated Thyroid Cancer

Sites in Memphis +4 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 99

Code: NCT05783323·Phase 2·Recruiting·Listed Mar 2023

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Molecular Analysis Of Solid Tumors

for Pediatric Solid Tumors

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 25

Code: NCT01050296·Recruiting·Listed Jan 2010

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Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

for Pulmonary Invasive Fungal Infections

Sites in Memphis, Nashville +25 more locations

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 120 Days - 21

Code: NCT03827694·Recruiting·Listed Feb 2019

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Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

Sites in Memphis +28 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting·Listed Jul 2022

Apply to this trial

Screen2Prevent (S2P)

for HIV Infections

Sites in Memphis +4 more locations

Sponsor: Westat

Sex: All·Age: 14 - 24·Accepts healthy volunteers

Code: NCT07728123·Recruiting·Listed Jul 2026

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Insights From Bereaved Parents and Oncologists

for Communication

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+

Code: NCT07663539·Recruiting·Listed Jun 2026

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Muscle Aging Phenotypes in Childhood Cancer Survivors

for Muscle Weakness

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07531498·Recruiting·Listed Apr 2026

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Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

for Pediatric Solid Tumors

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT07514819·Recruiting·Listed Apr 2026

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A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 29 Days - 21

Code: NCT05955261·Phase 2·Recruiting·Listed Jul 2023

Apply to this trial