Paid Clinical Trials in Nashville, TN
As of June 2026, 1,408 paid clinical trials are recruiting in Nashville, Tennessee. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Nashville offers studies at sites including Vanderbilt University Medical Center for conditions such as Breast Cancer, Advanced Solid Tumor, Colorectal Cancer, Ovarian Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Nashville
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·Clear filters·↓ Download CSVAbout research studies in Nashville
Nashville has approximately 1,408 recruiting research studies across a wide range of therapeutic areas. Tennessee is home to Vanderbilt University Medical Center and St. Jude Children's Research Hospital — world leaders in pediatric oncology and personalized medicine.
Top Research Study Locations in Nashville
Researchers run research studies in Nashville, TN at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Vanderbilt University Medical Center | Parkinson Disease, Colorectal Cancer, Obesity | 377 |
| SCRI Oncology Partners | Breast Cancer, Advanced Solid Tumor, Colorectal Cancer | 120 |
| Vanderbilt University/Ingram Cancer Center | Metastatic Malignant Solid Neoplasm, Stage IV Colorectal Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma | 94 |
| Sarah Cannon Research Institute | Advanced Solid Tumor, Colorectal Cancer, Advanced Solid Tumors | 63 |
| Vanderbilt University | Breast Cancer, Cardiac Failure, Graft Rejection | 60 |
| Tennessee Oncology | Breast Cancer, Multiple Myeloma, Carcinoma, Non-Small-Cell Lung | 55 |
| Vanderbilt-Ingram Cancer Center | Breast Cancer, Colorectal Cancer, Endometrial Cancer | 40 |
| The Children's Hospital at TriStar Centennial | Malignant Solid Neoplasm, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 27 |
| Monroe Carell Jr. Children's Hospital at Vanderbilt | Hypertension, Acute Kidney Injury, Acute Myeloid Leukemia | 17 |
| Tennessee Oncology, PLLC | Advanced Solid Tumor, Breast Cancer, Metastatic Breast Cancer | 17 |
| TriStar Centennial Medical Center | Acute Lower Limb Arterial Occlusion, Acute Myeloid Leukemia (AML), Aortic Stenosis | 16 |
| Vanderbilt Breast Center at One Hundred Oaks | Metastatic Malignant Solid Neoplasm, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 15 |
| Tennessee Valley Healthcare System Nashville Campus, Nashville, TN | Cardiovascular Disease, Acute Kidney Injury (AKI), Aging | 12 |
| Tennessee Retina, PC | Geographic Atrophy, Neovascular Age-Related Macular Degeneration (nAMD), AMD | 9 |
| Ascension Saint Thomas | Coronary Artery Disease, Mitral Regurgitation, Atrial Fibrillation, Postoperative | 8 |
| GSK Investigational Site | Neoplasms, Hypereosinophilic Syndrome, Multiple Myeloma | 8 |
| Vanderbilt Eye Institute | Macular Edema Secondary to Inflammation, Age-related Macular Degeneration (AMD), Diabetic Retinopathy | 8 |
| Vanderbilt Ingram Cancer Center | AL Amyloidosis, Adamantinomatous Craniopharyngioma, Advanced Solid Tumors | 8 |
| Sarah Cannon Research Institute (SCRI) Oncology Partners | Metastatic Solid Tumor, Ovarian Cancer, Advanced NRAS-Mutant Melanoma | 7 |
| Sarah Cannon Research Institute - Pharmacy | Gastroesophageal Junction Adenocarcinoma, Breast Neoplasms, Stomach Neoplasms | 7 |
| Urology Associates, P.C. | NMIBC, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ, Cancer of the Prostate | 7 |
| TriStar Bone Marrow Transplant | Acute Myeloid Leukemia, AML With Mutated NPM1, Acute Biphenotypic Leukemia | 7 |
| Autonomic Dysfunction Center/ Vanderbilt University Medical Center | Autonomic Failure, Multiple System Atrophy, Pure Autonomic Failure | 6 |
| Centennial Medical Center | Cardiovascular Diseases, Coronary Artery Disease, Heart Failure | 6 |
| Henry-Joyce Cancer Clinic | Colorectal Neoplasms, Multiple Myeloma, Breast Cancer | 6 |
| Meharry Medical College | ARDS, Cardiovascular Diseases, Cognitive Impairment, Mild | 6 |
| Vanderbilt Medical Center | Alzheimer Disease, Alzheimer Disease, Early Onset, Amputation | 6 |
| Access Clinical Trials, Inc. | Acute Treatment of Migraine, Pediatric Migraine, Migraine | 6 |
| Monroe Carrell Jr. Children's Hospital at Vanderbilt | Neuroblastoma, Ewing Sarcoma, Osteosarcoma | 5 |
| Saint Thomas Health | Aortic Valve Stenosis, Aortic Stenosis, Calcific, Aortic Valve Insufficiency | 5 |
| Sarah Cannon Research Institute (SCRI) | Ovarian Cancer, Triple Negative Breast Cancer, Adenoid Cystic Carcinoma | 5 |
| Sarah Cannon Research Institute Oncology Partners | Advanced Solid Tumors, Advanced Cancer, FGF19 Gene Amplification | 5 |
| Tennessee Retina | Diabetic Macular Edema, DME, Diabetic Macular Edema (DME) | 5 |
| Tennessee Retina PC | Macular Edema Secondary to Inflammation, Geographic Atrophy, Neovascular Age-Related Macular Degeneration | 5 |
| Vanderbilt - Ingram Cancer Center | Acute Myeloid Leukemia, Advanced Solid Tumor, Beta-thalassemia | 5 |
| Vanderbilt University School of Medicine | Colorectal Adenocarcinoma, Colorectal Cancer, Ewing Sarcoma | 5 |
| Clinical Trial Site | Advanced Breast Cancer, Breast Cancer, ER Positive Breast Cancer | 4 |
| Nashville VA Medical Center | Acute Kidney Injury, Cardiovascular Diseases, Cognitive Impairment, Mild | 4 |
| Quality Medical Research | Obesity, Overweight, Eosinophilic Esophagitis | 4 |
| United States Oncology Regulatory Affairs Corporate Office | Extensive Stage Small-cell Lung Cancer, Metastatic Castration-resistant Prostate Cancer, Non-Small Cell Lung Cancer (NSCLC) | 4 |
| Vanderbilt Children's Hospital | Amblyopia, Chronic Thromboembolic Pulmonary Hypertension, Cystic Fibrosis | 4 |
| Veterans Affairs Medical Center - Nashville | Lung Cancer, Colorectal Cancer, Esophageal Cancer | 4 |
| Ascension Saint Thomas Hospital | Coronary Artery Disease, Pulmonary Embolism | 3 |
| Clinical Research Associates | Diabetes Mellitus, Type 2, Obesity, Obesity or Overweight | 3 |
| Monroe Carell Jr Children's Hospital at Vanderbilt | Asthma, Bronchiolitis, Viral, Firearm Injury | 3 |
| Nashville Breast Center | Breast Cancer, DCIS, Ductal Breast Carcinoma In Situ | 3 |
| Saint Thomas Research Institute | Heart Failure With Preserved Ejection Fraction (HFpEF), Symptomatic Functional MR 3 or Greater, Tachyarrhythmia | 3 |
| Sarah Cannon | Advanced Solid Tumor, Graft-versus-host Disease (GVHD), Locally Advanced Solid Tumor | 3 |
| Sarah Cannon Research Institute - Oncology Partners | Advanced Pancreatic Ductal Adenocarcinoma, Biliary Tract Cancer, Esophageal Adenocarcinoma | 3 |
| Sarah Cannon Research Institute / Tennessee Oncology | Advanced Liver Cancers, Breast Cancer, Metastatic Breast Cancer | 3 |
Active & Upcoming Studies in Nashville (2026)
Recruiting trials in Nashville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (585 active studies)
- Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy · Phase 2 · National Cancer Institute (NCI)
- A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 ) · Phase 1 · Eli Lilly and Company
Cardiovascular (85 active studies)
- Improving Veteran Referral to Cardiac Rehabilitation · VA Office of Research and Development
- Health Enhanced Artery Risk Tracking With Widespread Implementation and Screening Effort in ASCVD (HEARTWISE-ASCVD) · Stanford University
Neurology & pain (67 active studies)
- Individual vs Co-Treatment in Acute Stroke Rehabilitation and Evaluation · Vanderbilt University Medical Center
- Cholinergic Deep Brain Stimulation for Alzheimer's Disease · Vanderbilt University Medical Center
Diabetes & metabolic (51 active studies)
- A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 Diabetes · Phase 2 · Novo Nordisk A/S
- Transition to Ambulatory Bariatric Surgery (TABS) Trial · Vanderbilt University Medical Center
Eye & vision (21 active studies)
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
- Clinical Evaluation of Lifitegrast Ophthalmic Solution 5.0% in Dry Eye Disease Using In Vivo Confocal Microscopy · Phase 4 · Toyos Clinic
Mental health & behavior (13 active studies)
- Cognitive Enhancement in Recurrent Depression (The COG-D-R Study) · Vanderbilt University Medical Center
- GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV · Phase 2 · Vanderbilt University Medical Center
Vaccines (11 active studies)
- Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS · Phase 2 · Vanderbilt University Medical Center
- High vs. Standard Dose Influenza Vaccines in Lung Transplant (Repeater) · Phase 2 · Vanderbilt University Medical Center
HIV / STI (10 active studies)
- Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV · Phase 2 · National Institute of Allergy and Infectious Diseases (NIAID)
- GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV · Phase 2 · Vanderbilt University Medical Center
Pediatric (10 active studies)
- Neonatal Platelet Transfusion Threshold Trial · NICHD Neonatal Research Network
- Project PAIR: Parent-implemented Articulation Intervention With Recast · Vanderbilt University
Common conditions studied in Nashville
- Breast Cancer (44 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Advanced Solid Tumor (33 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Colorectal Cancer (29 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Ovarian Cancer (26 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Advanced Solid Tumors (25 active studies). Recruiting Advanced Solid Tumors studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Endometrial Cancer (22 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Nashville
- Vanderbilt University Medical Center
- AstraZeneca
- National Cancer Institute (NCI)
- Vanderbilt-Ingram Cancer Center
- Eli Lilly and Company
Local regulations and guidelines
Clinical trials in Tennessee are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Tennessee research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Nashville. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Nashville
Hipa.ai aggregates every recruiting study in Nashville from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Nashville?
There are approximately 1,408 recruiting clinical trials in Nashville, Tennessee listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Nashville pay participants?
Most recruiting trials in Nashville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Nashville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Nashville?
The most common conditions under active study in Nashville include Breast Cancer (44), Advanced Solid Tumor (33), Colorectal Cancer (29), Ovarian Cancer (26), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Nashville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Nashville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Nashville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Nashville?
Recruiting research sites in Nashville include Vanderbilt University Medical Center, SCRI Oncology Partners, Vanderbilt University/Ingram Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Nashville right now?
The largest active categories in Nashville are Cancer & tumors (585), Cardiovascular (85), Neurology & pain (67). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.