MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Ontario, Baker City +2341 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Paid Clinical Trials in Ontario, OR
As of July 2026, 52 paid clinical trials are recruiting in Ontario, Oregon. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Ontario offers studies at sites including Saint Alphonsus Cancer Care Center-Ontario for conditions such as Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Recurrent Lung Non-Small Cell Carcinoma, Anatomic Stage II Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Ontario
Trials by drug in Ontario
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52 clinical trials
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
for Chronic Lymphocytic Leukemia
Drug: Sonrotoclax
Sites in Ontario, Baker City +150 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 65+
Code: NCT07321652·Phase 3·Recruiting·Listed Jan 2026
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
for Ampulla of Vater Carcinoma
Sites in Ontario, Baker City +330 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07283939·Recruiting·Listed Dec 2025
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in Ontario, Portland +633 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Family Communications After Genetic Testing
for Colon Adenocarcinoma
Sites in Ontario, Baker City +273 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07143487·Recruiting·Listed Aug 2025
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Ontario, Baker City +1103 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
for Chronic Lymphocytic Leukemia
Sites in Ontario, Bend +296 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
for Miscellaneous Neoplasm, Nos
Sites in Ontario, Baker City +277 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07091617·Recruiting·Listed Jul 2025
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Ontario, Hood River +920 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
for Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Drug: Bevacizumab
Sites in Ontario, Bend +326 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04181060·Phase 3·Recruiting·Listed Nov 2019
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
for Head and Neck Squamous Cell Carcinoma
Sites in Ontario, Baker City +464 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Ontario, Bend +774 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
for Intracranial Meningioma
Sites in Ontario, Baker City +454 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Ontario, Baker City +641 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
Sites in Ontario, Baker City +629 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Ontario, Bend +525 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects
for Malignancy
Sites in Ontario, Baker City +403 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: All ages
Code: NCT04242095·Recruiting·Listed Jan 2020
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Ontario, Oregon City +445 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
for Plasma Cell Myeloma
Sites in Ontario, Baker City +226 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT04566328·Phase 3·Recruiting·Listed Sep 2020
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for Advanced Malignant Solid Neoplasm
Sites in Ontario, Oregon City +429 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: All ages
Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
for Bladder Adenocarcinoma
Drug: Cabozantinib
Sites in Ontario, Oregon City +223 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03866382·Phase 2·Recruiting·Listed Mar 2019
Mobile Health for Adherence in Breast Cancer Patients
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in Ontario, Baker City +457 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06112613·Recruiting·Listed Nov 2023
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
for Acute Myeloid Leukemia
Sites in Ontario, Oregon City +326 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022
Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma
for Mantle Cell Lymphoma
Sites in Ontario, Oregon City +225 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 60+
Code: NCT05976763·Phase 3·Recruiting·Listed Aug 2023
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
for B Acute Lymphoblastic Leukemia
Sites in Ontario, Portland +154 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18 - 39
Code: NCT03150693·Phase 3·Recruiting·Listed May 2017
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
for Clinical Stage III Cutaneous Melanoma AJCC v8
Drug: Cabozantinib
Sites in Ontario, Bend +204 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05136196·Phase 2·Recruiting·Listed Nov 2021
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
for Advanced Lung Non-Small Cell Carcinoma
Sites in Ontario +268 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 70+
Code: NCT06096844·Phase 3·Recruiting·Listed Oct 2023
Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change
for Advanced Lung Non-Small Cell Carcinoma
Drug: Osimertinib
Sites in Ontario, Baker City +217 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03191149·Phase 2·Recruiting·Listed Jun 2017
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
for Previously Treated Non-Small Cell Lung Cancer
Sites in Ontario, Baker City +948 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in Ontario, Oregon City +221 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06317649·Phase 2·Recruiting·Listed Mar 2024
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
for Pancreatic Neoplasm
Sites in Ontario, Baker City +334 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 50 - 75
Code: NCT04239573·Recruiting·Listed Jan 2020
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Ontario, Oregon City +344 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06203600·Phase 2, Phase 3·Recruiting·Listed Jan 2024
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
for Refractory Differentiated Thyroid Gland Carcinoma
Sites in Ontario, Baker City +286 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT06475989·Phase 3·Recruiting·Listed Jun 2024
Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma
for Classic Follicular Lymphoma
Drug: Mosunetuzumab
Sites in Ontario, Oregon City +247 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06337318·Phase 3·Recruiting·Listed Mar 2024
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
for Recurrent Lung Non-Small Cell Carcinoma
Sites in Ontario, Oregon City +370 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT05642572·Phase 2·Recruiting·Listed Dec 2022
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
for Malignant Female Reproductive System Neoplasm
Sites in Ontario, Portland +173 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06126276·Phase 2·Recruiting·Listed Nov 2023
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment
for Metastatic Head and Neck Squamous Cell Carcinoma
Sites in Ontario, Oregon City +183 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06589804·Phase 3·Recruiting·Listed Sep 2024
Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Sites in Ontario, Portland +207 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 59
Code: NCT05554406·Phase 2·Recruiting·Listed Sep 2022
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in Ontario, Portland +162 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 59
Code: NCT05554393·Phase 2·Recruiting·Listed Sep 2022
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
for Malignant Solid Neoplasm
Sites in Ontario, Baker City +586 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04871542·Recruiting·Listed May 2021
Top Research Study Locations in Ontario
Researchers run research studies in Ontario, OR at 3 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Saint Alphonsus Cancer Care Center-Ontario | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Recurrent Lung Non-Small Cell Carcinoma | 48 |
| Saint Alphonsus Medical Center-Ontario | Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | 3 |
| Saint Alphonsus Medical Center Ontario | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Ontario (2026)
Recruiting trials in Ontario grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (44 active studies)
- Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL · Phase 3 · Alliance for Clinical Trials in Oncology
- Family Communications After Genetic Testing · Alliance for Clinical Trials in Oncology
Common conditions studied in Ontario
- Acute Myeloid Leukemia (5 active studies)
- Stage IV Lung Cancer AJCC v8 (5 active studies)
- Recurrent Lung Non-Small Cell Carcinoma (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Anatomic Stage IV Breast Cancer AJCC v8 (3 active studies)
- Chronic Lymphocytic Leukemia (3 active studies)
Leading research sponsors in Ontario
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- ECOG-ACRIN Cancer Research Group
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Ontario?
There are approximately 52 recruiting clinical trials in Ontario, Oregon listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Ontario pay participants?
Most recruiting trials in Ontario compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Ontario?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Ontario?
The most common conditions under active study in Ontario include Acute Myeloid Leukemia (5), Stage IV Lung Cancer AJCC v8 (5), Recurrent Lung Non-Small Cell Carcinoma (4), Anatomic Stage II Breast Cancer AJCC v8 (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Ontario?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Ontario on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Ontario?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Ontario?
Recruiting research sites in Ontario include Saint Alphonsus Cancer Care Center-Ontario, Saint Alphonsus Medical Center-Ontario, Saint Alphonsus Medical Center Ontario, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Ontario right now?
The largest active categories in Ontario are Cancer & tumors (44). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
Other cities in Oregon
Portland, OR(1,000)Eugene, OR(130)Newberg, OR(73)Oregon City, OR(70)Bend, OR(58)Clackamas, OR(55)Springfield, OR(35)Coos Bay, OR(31)Redmond, OR(30)Hood River, OR(28)Medford, OR(28)Baker City, OR(27)Salem, OR(23)Gresham, OR(22)Tualatin, OR(19)Tigard, OR(18)Corvallis, OR(16)Klamath Falls, OR(7)Albany, OR(5)Hillsboro, OR(5)Grants Pass, OR(4)Happy Valley, OR(4)Beaverton, OR(3)Warrenton, OR(3)Wilsonville, OR(2)Astoria, OR(1)Cottage Grove, OR(1)Forest Grove, OR(1)Hermiston, OR(1)Milwaukie, OR(1)Multiple Locations, OR(1)Portand, OR(1)Roseburg, OR(1)The Dalles, OR(1)White City, OR(1)