Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,479 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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3,012 clinical trials

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A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)

for Post-Stroke Spasticity

1 location in Elkins Park

Sponsor: Alberto Esquenazi

Sex: All·Age: 18 - 80

Code: NCT07704840·Phase 2·Recruiting·Listed Jul 15, 2026

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Low Dose Radiotherapy for Osteoarthritis

for Osteoarthitis

2 locations in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07715188·Recruiting·Listed Jul 20, 2026

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A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

for Acute Migraine

Drug: Elismetrep

Sites in Philadelphia, Pittsburgh +111 more locations

Sponsor: Kallyope Inc.

Sex: All·Age: 18+

Code: NCT07674654·Phase 3·Recruiting·Listed Jun 2026

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Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease

for Graves' Disease

Sites in Sayre +25 more locations

Sponsor: Yarrow Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT07682896·Phase 2·Recruiting·Listed Jul 2026

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BCAAs in Concussion 3.0

for Concussion (Diagnosis)

1 location in Havertown

Sponsor: Akiva Cohen

Sex: All·Age: 11 - 23·Accepts healthy volunteers

Code: NCT07670195·Phase 2·Recruiting·Listed Jun 2026

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Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

for Diffuse Intrinsic Pontine Glioma

Sites in Philadelphia +5 more locations

Sponsor: BrainChild Bio, Inc

Sex: All·Age: 1 - 26

Code: NCT07680439·Phase 2·Recruiting·Listed Jul 2026

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Study of LNP.UCD.ABE in Patients With Urea Cycle Disorders

for Urea Cycle Disorders

1 location in Philadelphia

Sponsor: Rebecca Ahrens-Nicklas

Sex: All·Age: 24 Hours - 5

Code: NCT07667387·Phase 1, Phase 2·Recruiting·Listed Jun 2026

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BOdygUardian MOnitoriNg for ReCurrencE of AF

for Atrial Fibrillation (AF)

Sites in Pittsburgh +4 more locations

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT07671677·Recruiting·Listed Jun 2026

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A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

for Obesity

Sites in Philadelphia +73 more locations

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All·Age: 18 - 79·Accepts healthy volunteers

Code: NCT07654374·Phase 3·Recruiting·Listed Jun 2026

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A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed

for HIV Infections

Sites in Philadelphia +34 more locations

Sponsor: ViiV Healthcare

Sex: All·Age: 12+

Code: NCT07650916·Phase 3·Recruiting·Listed Jun 2026

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Cryoablation for Monomorphic Ventricular Tachycardia (VTS)

for Ventricular Tachycardia, Sustained

Sites in Philadelphia +7 more locations

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT07650032·Recruiting·Listed Jun 2026

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Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

for Obesity

Sites in Philadelphia +70 more locations

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All·Age: 18 - 79

Code: NCT07654361·Phase 3·Recruiting·Listed Jun 2026

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A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain

for Chronic Pain

Drug: LY4065967

Sites in Duncansville +35 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07641504·Phase 2·Recruiting·Listed Jun 2026

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A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain

for Osteoarthritis, Knee

Drug: LY4065967

Sites in Duncansville +35 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 40+

Code: NCT07641517·Phase 2·Recruiting·Listed Jun 2026

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A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

for Weight Management

Sites in Philadelphia, DuBois +53 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07667803·Phase 3·Recruiting·Listed Jun 2026

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Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients

for Head and Neck Disorder

1 location in Pittsburgh

Sponsor: Matthew Spector

Sex: All·Age: 18+

Code: NCT07631650·Phase 2·Recruiting·Listed Jun 2026

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A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Semaglutide

Sites in Philadelphia, Feasterville-Trevose +61 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662213·Phase 3·Recruiting·Listed Jun 2026

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A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

for Essential Thrombocythemia

Sites in Philadelphia +40 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07623200·Phase 3·Recruiting·Listed Jun 2026

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A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Philadelphia, Pittsburgh +28 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07623161·Phase 3·Recruiting·Listed Jun 2026

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A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information

for Clinical Stage 0 Cutaneous Melanoma AJCC v8

Sites in Philadelphia, Pittsburgh +3 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT07621614·Recruiting·Listed Jun 2026

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STEPS - Stress Training and Engagement Via Phone-Based Systems

for Psychological Distress

1 location in Pittsburgh

Sponsor: Equa Health

Sex: All·Age: 18 - 30

Code: NCT07639697·Recruiting·Listed Jun 2026

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AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

Sites in Pittsburgh +24 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting·Listed May 2026

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A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Philadelphia, Bethlehem +33 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07652658·Phase 2·Recruiting·Listed Jun 2026

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Periprosthetic Joint Infection Bubble Study

for Periprosthetic Joint Infection (PJI)

Sites in Philadelphia, Pittsburgh +1 more location

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07599865·Phase 2·Recruiting·Listed May 2026

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Mobile Health Program for Post-Preeclampsia Hypertension

for Hypertension (HTN)

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18+

Code: NCT07599579·Recruiting·Listed May 2026

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Automated IADL Sensing to Refine Measurement of Older Adult Daily Activity

for Cognitive Ability General

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 75+·Accepts healthy volunteers

Code: NCT07585864·Recruiting·Listed May 2026

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Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

for Pediatric Asthma

Sites in Philadelphia +2 more locations

Sponsor: Columbia University

Sex: All·Age: 5 - 17

Code: NCT07582211·Recruiting·Listed May 2026

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ReneuRx™ (Nerve Selective Therapy) Utilized in Lateral Hip Pain

for Greater Trochanteric Pain Syndrome

Sites in Sewickley, King of Prussia +9 more locations

Sponsor: Brixton Biosciences, Inc.

Sex: All·Age: 22 - 80

Code: NCT07568015·Recruiting·Listed May 2026

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A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies

for HIV

Sites in Philadelphia, Pittsburgh +10 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 60

Code: NCT07569029·Phase 1·Recruiting·Listed May 2026

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Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion

for Mild Autonomous Cortisol Secretion (MACS)

Drug: Tirzepatide

1 location in Pittsburgh

Sponsor: Alaa Sada

Sex: All·Age: 18+

Code: NCT07573163·Phase 2·Recruiting·Listed May 2026

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DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer (epNEC)

Drug: Obrixtamig

Sites in Pittsburgh +19 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Recruiting·Listed Apr 2026

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Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care

for Severe Mental Illness

Sites in Philadelphia +1 more location

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07549178·Recruiting·Listed Apr 2026

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A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression

for Ovarian Cancer

Sites in Philadelphia, Willow Grove +10 more locations

Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female·Age: 18+

Code: NCT07546500·Phase 3·Recruiting·Listed Apr 2026

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Creation of a Decision Aid for Coronary Anomalies

for AAOCA

Sites in Philadelphia +4 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 10 - 35

Code: NCT07544979·Recruiting·Listed Apr 2026

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Real World Evidence of SI-BONE's iFuse TORQ TNT Advancing Treatment of Pelvic Ring Fractures

for Fracture

Sites in Wyomissing +1 more location

Sponsor: SI-BONE, Inc.

Sex: All·Age: 60+

Code: NCT07530497·Recruiting·Listed Apr 2026

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Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies

for B-cell Lymphoma

Sites in Pittsburgh +5 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07520006·Phase 1, Phase 2·Recruiting·Listed Apr 2026

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A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma

for Severe Asthma

Drug: Frevecitinib

Sites in Pittsburgh +13 more locations

Sponsor: Kinaset Therapeutics Inc

Sex: All·Age: 18 - 75

Code: NCT07532265·Phase 2·Recruiting·Listed Apr 2026

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A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

for Atherosclerosis

Sites in Camp Hill +11 more locations

Sponsor: Beijing Inno Medicine Co., Ltd.

Sex: All·Age: 18 - 80

Code: NCT07521007·Phase 2·Recruiting·Listed Apr 2026

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A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With α- or β-Non-Transfusion-Dependent Thalassemia

for Non-Transfusion-dependent Alpha-Thalassemia

Drug: Mitapivat

Sites in Philadelphia +3 more locations

Sponsor: Agios Pharmaceuticals, Inc.

Sex: All·Age: 1 - 17

Code: NCT07517133·Phase 3·Recruiting·Listed Apr 2026

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ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile Infection Recurrence

Sites in Pittsburgh +14 more locations

Sponsor: Acurx Pharmaceuticals Inc.

Sex: All·Age: 18 - 90

Code: NCT07513285·Phase 2·Recruiting·Listed Apr 2026

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