Blood cancer Clinical Trials in Philadelphia, PA

As of August 2026, 76 paid clinical trials are recruiting for Blood cancer in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

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77 clinical trials for Blood cancer

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Philadelphia +44 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

Sites in Philadelphia, Allentown +154 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021

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Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Sites in Philadelphia, Danville +34 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 25

Code: NCT07022678·Phase 3·Recruiting·Listed Jun 2025

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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for Lymphoma, Non-Hodgkin

Sites in Philadelphia, Allentown +144 more locations

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 12+

Code: NCT02693535·Phase 2·Recruiting·Listed Feb 2016

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Philadelphia, Hershey +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

for Refractory Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Philadelphia +9 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 30

Code: NCT06177067·Phase 1·Recruiting·Listed Dec 2023

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A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for Acute Myeloid Leukemia Post Cytotoxic Therapy

Sites in Philadelphia, Pittsburgh +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT07012044·Phase 1·Recruiting·Listed Jun 2025

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

Sites in Philadelphia, Allentown +39 more locations

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting·Listed Feb 2022

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Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

for AIDS-Related Diffuse Large B-cell Lymphoma

Sites in Philadelphia +6 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05077527·Phase 1·Recruiting·Listed Oct 2021

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Allergy Delabeling in Antibiotic Stewardship - Intervention

for Beta Lactam Allergy

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07133074·Phase 4·Recruiting·Listed Aug 2025

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Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Philadelphia +6 more locations

Sponsor: Joshua Zeidner

Sex: All·Age: 18+

Code: NCT05442216·Phase 2·Recruiting·Listed Jul 2022

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CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT

for Acute Leukemia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 25

Code: NCT03810196·Recruiting·Listed Jan 2019

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Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for Hematologic Malignancy

Drug: Venetoclax

Sites in Philadelphia +4 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 0 - 38

Code: NCT06131801·Recruiting·Listed Nov 2023

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Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

for B-ALL

Sites in Philadelphia +5 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT06579469·Recruiting·Listed Aug 2024

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Epcoritamab-CAR T Cells for Large B-cell Lymphomas

for Lymphoma, Non-Hodgkin

Drug: Epcoritamab

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06458439·Phase 2·Recruiting·Listed Jun 2024

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CAR-T Followed by Bispecific Antibodies

for Large B-cell Lymphoma

Sites in Philadelphia +1 more location

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04889716·Phase 2·Recruiting·Listed May 2021

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SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia With FLT3/ITD Mutation

Sites in Philadelphia +3 more locations

Sponsor: Uma Borate

Sex: All·Age: 18+

Code: NCT06222580·Phase 1·Recruiting·Listed Jan 2024

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in Philadelphia +27 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting·Listed Feb 2023

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

Sites in Philadelphia, Wilkes-Barre +81 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting·Listed Dec 2022

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Philadelphia, Hershey +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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Massage Impact on Sleep in Pediatric Oncology

for Cancer

Sites in Philadelphia +1 more location

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12 - 21

Code: NCT06892158·Recruiting·Listed Mar 2025

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Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

for Leukemia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 25

Code: NCT06839456·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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Tazemetostat and Palbociclib With CPX-351for R/R AML

for Recurrent Acute Myeloid Leukemia

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05627232·Phase 1·Recruiting·Listed Nov 2022

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Mozobil for Autologous Hematopoietic Stem Cell Transplantation

for Multiple Myeloma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07188090·Phase 2·Recruiting·Listed Sep 2025

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BHB & CAR-T for Lymphomas

for Large B-cell Lymphoma

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06610344·Recruiting·Listed Sep 2024

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Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

for Leukemia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 30

Code: NCT02356653·EARLY_Phase 1·Recruiting·Listed Feb 2015

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Home Blood Transfusions

for Hematologic Malignancy

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07121140·Recruiting·Listed Aug 2025

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Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition

for Primary Myelofibrosis

Drug: Pacritinib

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT06218628·Phase 1·Recruiting·Listed Jan 2024

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Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

Sites in Philadelphia +2 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting·Listed Jan 2022

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Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

Sites in Philadelphia +28 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting·Listed Jul 2022

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A Phase I Safety and Pharmacokinetic Study of Gamitrinib Administered Intravenously to Patients With Advanced Cancer

for Lymphoma

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT04827810·Phase 1·Recruiting·Listed Apr 2021

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A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Philadelphia, Pittsburgh +28 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07623161·Phase 3·Recruiting·Listed Jun 2026

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Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After Treatment

for Recurrent Multiple Myeloma

Drug: Teclistamab

1 location in Philadelphia

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07463807·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

for Multiple Myeloma

Sites in Philadelphia +7 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06106945·Phase 1, Phase 2·Recruiting·Listed Oct 2023

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A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for Chronic Lymphocytic Leukaemia

Sites in Philadelphia, Pittsburgh +10 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06564038·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

for Lymphoma

Sites in Philadelphia +6 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT06137144·Phase 1, Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

Conditions in Blood cancer (Philadelphia, PA)

Acute myeloid leukemia (AML)· 24 Non-Hodgkin lymphoma· 18 Diffuse large B-cell lymphoma (DLBCL)· 13 Hematologic malignancy· 12 Multiple myeloma· 11 Myelodysplastic syndromes (MDS)· 10 Leukemia (other)· 9 Chronic lymphocytic leukemia (CLL)· 7 Hodgkin lymphoma· 6 Acute lymphoblastic leukemia· 4 Myelofibrosis· 4 Small lymphocytic lymphoma· 4 Myeloproliferative neoplasm· 3 Follicular lymphoma· 3 Burkitt lymphoma· 3 Mantle cell lymphoma· 2 Marginal zone lymphoma· 2 Chronic myelomonocytic leukemia· 1