Acute myeloid leukemia (AML) Clinical Trials in Philadelphia, PA
As of September 2026, 22 paid clinical trials are recruiting for Acute myeloid leukemia (AML) in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Philadelphia
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
23 clinical trials for Acute myeloid leukemia (AML)
·Clear filters·A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia
Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia
Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents
CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT
Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation
Massage Impact on Sleep in Pediatric Oncology
Tazemetostat and Palbociclib With CPX-351for R/R AML
Home Blood Transfusions
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Top Research Study Locations in Philadelphia
Researchers run research studies in Philadelphia, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pennsylvania | Heart Failure, Opioid Use Disorder, Colorectal Cancer | 358 |
| Children's Hospital of Philadelphia | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Pediatric Cancer | 307 |
| Thomas Jefferson University Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 109 |
| Fox Chase Cancer Center | Breast Cancer, Cancer, Urothelial Carcinoma | 96 |
| Thomas Jefferson University | Focal Epilepsy, Advanced Melanoma, Cancer | 96 |
| Hospital of the University of Pennsylvania | Abdominal Aortic Aneurysm, Breast Cancer, Aortic Dissection | 87 |
| Temple University | Amyotrophic Lateral Sclerosis, COPD, Emphysema | 41 |
| The Children's Hospital of Philadelphia | Mitochondrial Diseases, Primary Mitochondrial Disease, 4H Syndrome | 40 |
| Temple University Hospital | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, COPD | 35 |
| University of Pennsylvania/Abramson Cancer Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 31 |
| Pennsylvania Hospital | Stroke, Acute, Activity Restriction, Advanced Cancer | 28 |
| Abramson Cancer Center of the University of Pennsylvania | Breast Cancer, Advanced Solid Tumor, DLBCL - Diffuse Large B Cell Lymphoma | 25 |
| Penn Presbyterian Medical Center | Heart Failure, ADHF, Acute Respiratory Failure | 25 |
| Jefferson Torresdale Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 23 |
| Saint Christopher's Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 22 |
| Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA | Parkinson Disease, Stress Disorders, Post-Traumatic, Advanced Urothelial Carcinoma | 19 |
| Sidney Kimmel Cancer Center at Thomas Jefferson University | Breast Cancer, Colorectal Cancer, Hormone Receptor Positive Breast Carcinoma | 16 |
| Drexel University | Autism Spectrum Disorder, Obesity, Anxiety | 13 |
| Penn Medicine | Hypertension, ALS, Allogeneic Transplantation | 13 |
| University of Pennsylvania Hospital | Chronic Lymphocytic Leukemia, Neoplasm Metastasis, Non-Hodgkin Lymphoma | 13 |
| GSK Investigational Site | Asthma, Connective Tissue Diseases, Gastrointestinal Neoplasms | 12 |
| Childrens Hospital of Philadelphia | Suicide, Cardiac Arrest (CA), Cardiopulmonary Resuscitation (CPR) | 12 |
| University of Pennsylvania, Abramson Cancer Center | Advanced Solid Tumor, Biliary Tract Cancer, Breast Cancer | 12 |
| Abramson Cancer Center at University of Pennsylvania | Cardiotoxicity, Renal Cell Carcinoma, AML, Adult | 10 |
| Thomas Jefferson University, Sidney Kimmel Cancer Center | Advanced Solid Tumor, Colorectal Cancer, Bladder Cancer | 10 |
Active & Upcoming Studies in Philadelphia (2026)
Recruiting trials in Philadelphia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (556 active studies)
- Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After Treatment · Phase 1, Phase 2 · National Cancer Institute (NCI)
- The AYA Oncology Self-care Movement · Northwestern University
Neurology & pain (110 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease · Phase 4 · VA Office of Research and Development
Cardiovascular (109 active studies)
- Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass-Substudy · University of Pennsylvania
- A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF · Phase 3 · AstraZeneca
Diabetes & metabolic (63 active studies)
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities · Phase 3 · Ascletis Pharma (China) Co., Limited
Mental health & behavior (49 active studies)
- NST-SPARK Open-Label Phase 1 STTR (IGNITE) · North Shore Therapeutics, Inc.
- Effect of cTBS on Startle and TMS-evoked BOLD · University of Pennsylvania
Pediatric (47 active studies)
- Bilevel Positive Airway Pressure (BPAP) for Severe Asthma · Columbia University
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
HIV / STI (27 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy · International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Eye & vision (23 active studies)
- Penn SICCA Follow-up Study · University of Pennsylvania
- A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME) · Phase 1 · Genentech, Inc.
Vaccines (6 active studies)
- Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older · Phase 1, Phase 2 · Sanofi
- Flu Infection at UPHS · University of Pennsylvania
Common conditions studied in Philadelphia
- Breast Cancer (36 active studies)
- Cancer (25 active studies)
- Ovarian Cancer (22 active studies)
- Heart Failure (21 active studies)
- Prostate Cancer (21 active studies)
- Advanced Solid Tumor (18 active studies)
Leading research sponsors in Philadelphia
- University of Pennsylvania
- Abramson Cancer Center at Penn Medicine
- Children's Hospital of Philadelphia
- Thomas Jefferson University
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Philadelphia?
There are approximately 1,983 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Philadelphia pay participants?
Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Philadelphia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Philadelphia?
The most common conditions under active study in Philadelphia include Breast Cancer (36), Cancer (25), Ovarian Cancer (22), Heart Failure (21), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Philadelphia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Philadelphia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Philadelphia?
Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Philadelphia right now?
The largest active categories in Philadelphia are Cancer & tumors (556), Neurology & pain (110), Cardiovascular (109). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.