Breast oncology Clinical Trials in St Louis, MO

As of September 2026, 64 paid clinical trials are recruiting for Breast oncology in St Louis, Missouri. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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65 clinical trials for Breast oncology

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Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in St Louis, Creve Coeur +255 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024

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Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in St Louis, Creve Coeur +56 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500481·Phase 3·Recruiting·Listed Jul 2024

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The Vanguard Study: Testing a New Way to Screen for Cancer

for Bladder Carcinoma

Sites in St Louis, Kansas City +39 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT06995898·Recruiting·Listed May 2025

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

Sites in St Louis, Creve Coeur +21 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting·Listed Jul 2018

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Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

Drug: Pidnarulex

Sites in St Louis +1 more location

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07137416·Phase 1·Recruiting·Listed Aug 2025

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Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 70+

Code: NCT02476786·Phase 2·Recruiting·Listed Jun 2015

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Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

for Breast Atypical Ductal Hyperplasia

Sites in St Louis +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18 - 55

Code: NCT06184750·Phase 2·Recruiting·Listed Dec 2023

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in St Louis, Ballwin +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity Testing

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT04968964·Recruiting·Listed Jul 2021

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ChatGPT & Surgeon Synergy: Redefining Breast Reconstruction Consultations for Enhanced Patient Engagement and Satisfaction

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06981208·Recruiting·Listed May 2025

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COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05972343·Recruiting·Listed Aug 2023

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NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast Cancer

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 18+

Code: NCT05837455·Phase 2·Recruiting·Listed May 2023

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Cryoablation vs Lumpectomy in T1 Breast Cancers

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 50+

Code: NCT05505643·Recruiting·Listed Aug 2022

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Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

for Healthy Volunteer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04354064·Recruiting·Listed Apr 2020

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BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer

for Metastatic Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05977036·Recruiting·Listed Aug 2023

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WashU DIEP Flap Video and Patient Understanding Improvement

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 18+

Code: NCT06864754·Recruiting·Listed Mar 2025

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Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells

for Breast Neoplasms

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT00353483·Recruiting·Listed Jul 2006

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Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer

for Advanced Breast Cancer

Drug: Camizestrant

Sites in St Louis +2 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07427394·Phase 2·Recruiting·Listed Feb 2026

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A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

for Melanoma

Sites in St Louis +5 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07115043·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for Breast Cancer

Drug: Durvalumab

Sites in St Louis +35 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06103864·Phase 3·Recruiting·Listed Oct 2023

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A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

for Breast Cancer

Sites in St Louis +9 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05123482·Phase 1, Phase 2·Recruiting·Listed Nov 2021

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A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors

for Breast Cancer

Sites in St Louis +11 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05307705·Phase 1·Recruiting·Listed Apr 2022

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Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

for Advanced Breast Cancer

Drug: Camizestrant

Sites in St Louis, Springfield +36 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06380751·Phase 3·Recruiting·Listed Apr 2024

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Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in St Louis +7 more locations

Sponsor: MOMA Therapeutics

Sex: All·Age: 18+

Code: NCT06545942·Phase 1·Recruiting·Listed Aug 2024

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Conditions in Breast oncology (St Louis, MO)

Breast cancer· 50 Metastatic breast cancer· 16 Triple-negative breast cancer· 7 HER2-negative breast cancer· 3 HER2-positive breast cancer· 1