Solid tumor Clinical Trials in St Louis, MO

As of July 2026, 66 paid clinical trials are recruiting for Solid tumor in St Louis, Missouri. Recruiting Solid tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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66 clinical trials for Solid tumor

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JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration

for Advanced Solid Tumors

Sites in St Louis +3 more locations

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT06973564·Phase 1, Phase 2·Recruiting·Listed May 2025

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JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

for Solid Tumors

Sites in St Louis +3 more locations

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT05490472·Phase 1, Phase 2·Recruiting·Listed Aug 2022

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Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

for Solid Tumor, Adult

Sites in St Louis +3 more locations

Sponsor: Sairopa B.V.

Sex: All·Age: 18+

Code: NCT05856981·Phase 1·Recruiting·Listed May 2023

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

Sites in St Louis, Ballwin +629 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting·Listed Apr 2022

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

Sites in St Louis, Creve Coeur +428 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

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Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)

for Malignant Solid Neoplasm

Sites in St Louis, Ballwin +363 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06295367·Recruiting·Listed Mar 2024

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Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in St Louis, Creve Coeur +255 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

Sites in St Louis, Ballwin +586 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting·Listed May 2021

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Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

Drug: Pidnarulex

Sites in St Louis +1 more location

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07137416·Phase 1·Recruiting·Listed Aug 2025

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The Vanguard Study: Testing a New Way to Screen for Cancer

for Bladder Carcinoma

Sites in St Louis, Kansas City +37 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT06995898·Recruiting·Listed May 2025

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in St Louis, Columbia +231 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for Non-small Cell Lung Cancer

Sites in St Louis +19 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT05786924·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

Sites in St Louis, Creve Coeur +39 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting·Listed Jan 2019

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

Sites in St Louis, Creve Coeur +25 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting·Listed Mar 2024

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Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

for Hematologic Malignancy

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 8+

Code: NCT06689800·Recruiting·Listed Nov 2024

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in St Louis, Creve Coeur +178 more locations

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in St Louis, Kansas City +26 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting·Listed Feb 2023

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A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

for Wilms Tumor

Drug: Selinexor

Sites in St Louis +15 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 12 Months+

Code: NCT05985161·Phase 2·Recruiting·Listed Aug 2023

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Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

for Solid Tumor

Sites in St Louis +4 more locations

Sponsor: Emory University

Sex: All·Age: 1 - 30

Code: NCT04469530·Phase 2·Recruiting·Listed Jul 2020

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Collection and Storage of Tissue and Blood Samples From Patients With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in St Louis, Rolla +20 more locations

Sponsor: National Cancer Institute LAO

Sex: All·Age: 2 Months+

Code: NCT02474160·Recruiting·Listed Jun 2015

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First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for Esophageal Squamous Cell Carcinoma

Sites in St Louis +9 more locations

Sponsor: Plexium, Inc.

Sex: All·Age: 18+

Code: NCT07284186·Phase 1·Recruiting·Listed Dec 2025

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A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors

for Solid Tumor

Sites in St Louis +10 more locations

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06952010·Phase 1·Recruiting·Listed Apr 2025

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

Sites in St Louis +17 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting·Listed Jan 2024

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JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

for Solid Tumors

Sites in St Louis +4 more locations

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT06386146·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer

for Solid Tumor

Sites in St Louis +6 more locations

Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female·Age: 18+

Code: NCT04516447·Phase 1·Recruiting·Listed Aug 2020

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A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for Solid Tumor

Sites in St Louis +16 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06384807·Phase 1, Phase 2·Recruiting·Listed Apr 2024

Apply to this trial