Oncology Clinical Trials in Winston-Salem, NC

As of August 2026, 102 paid clinical trials are recruiting for Oncology in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

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102 clinical trials for Oncology

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

Sites in Winston-Salem, Chapel Hill +328 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

Sites in Winston-Salem, Clemmons +278 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting·Listed Apr 2022

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

Sites in Winston-Salem, High Point +429 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

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Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Sites in Winston-Salem, Charlotte +204 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554406·Phase 2·Recruiting·Listed Sep 2022

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Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Winston-Salem, Charlotte +214 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06317649·Phase 2·Recruiting·Listed Mar 2024

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Sites in Winston-Salem, High Point +144 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting·Listed Aug 2024

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Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Winston-Salem, Charlotte +167 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554393·Phase 2·Recruiting·Listed Sep 2022

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in Winston-Salem, Chapel Hill +189 more locations

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

Sites in Winston-Salem, Kernersville +115 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting·Listed Apr 2021

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Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Sites in Winston-Salem, Charlotte +127 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06672146·Phase 2·Recruiting·Listed Nov 2024

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

Sites in Winston-Salem, Chapel Hill +185 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting·Listed May 2019

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

Sites in Winston-Salem, Chapel Hill +167 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Winston-Salem, Chapel Hill +225 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

Sites in Winston-Salem, Chapel Hill +154 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Winston-Salem, Chapel Hill +200 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

Sites in Winston-Salem, Chapel Hill +152 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Winston-Salem, Chapel Hill +141 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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The Better, Harder, Faster, Stronger Study

for Frailty at Older Adults

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 55+

Code: NCT07220512·Recruiting·Listed Oct 2025

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Comprehensive Care for AYA: Needs Assessment Survey

for Cancer

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 15+

Code: NCT07196241·Recruiting·Listed Sep 2025

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Distance-Based Exercise to Preserve Function and Prevent Disability

for Localized Malignant Solid Neoplasm

Sites in Winston-Salem, Kernersville +16 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07059884·Recruiting·Listed Jul 2025

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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for Gastric Adenocarcinoma

Sites in Winston-Salem, Hillsborough +76 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT07001748·Phase 2, Phase 3·Recruiting·Listed Jun 2025

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A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for Glioblastoma

Sites in Winston-Salem +20 more locations

Sponsor: Global Coalition for Adaptive Research

Sex: All·Age: 18+

Code: NCT03970447·Phase 2, Phase 3·Recruiting·Listed May 2019

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A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients

for Lung Cancer

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 50 - 77

Code: NCT07322367·Recruiting·Listed Jan 2026

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Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway

for Cancer

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 65+

Code: NCT07175376·Recruiting·Listed Sep 2025

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A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

for Acute Myeloid Leukemia

Sites in Winston-Salem, Chapel Hill +19 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 75

Code: NCT05886049·Phase 1·Recruiting·Listed Jun 2023

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

Sites in Winston-Salem, Clemmons +21 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting·Listed Jul 2018

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LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients

for Sarcoma

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: All ages

Code: NCT06958107·Recruiting·Listed May 2025

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Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors

for Cancer

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06634381·Recruiting·Listed Oct 2024

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Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients

for Triple Negative Breast Cancer

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04677816·Phase 2·Recruiting·Listed Dec 2020

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Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery

for Head and Neck Cancer

Sites in Winston-Salem, Charlotte +1 more location

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06607406·Recruiting·Listed Sep 2024

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MRI in High-Grade Glioma Patients Undergoing Chemoradiation

for High Grade Glioma

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05212272·Recruiting·Listed Jan 2022

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Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

for Non-small Cell Lung Cancer

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06567704·Recruiting·Listed Aug 2024

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ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 64

Code: NCT06945042·Recruiting·Listed Apr 2025

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Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

for Head and Neck Squamous Cell Carcinoma

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04375384·Phase 2·Recruiting·Listed May 2020

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Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance

for Brain Metastases

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05692635·Phase 2·Recruiting·Listed Jan 2023

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Evaluation of the Pathobiology of CALR-mutated MPN Cells

for Myeloproliferative Neoplasm

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06480591·Recruiting·Listed Jun 2024

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Winston-Salem, Clemmons +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Winston-Salem, Chapel Hill +5 more locations

Sponsor: Joshua Zeidner

Sex: All·Age: 18+

Code: NCT05442216·Phase 2·Recruiting·Listed Jul 2022

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A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

for Oncology

Sites in Winston-Salem, Chapel Hill +2 more locations

Sponsor: University of Rochester

Sex: All·Age: 60+

Code: NCT06697600·Recruiting·Listed Nov 2024

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

Sites in Winston-Salem, Greensboro +36 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting·Listed Jun 2018

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Conditions in Oncology (Winston-Salem, NC)

Acute myeloid leukemia (AML)· 11 Non-small cell lung cancer (NSCLC)· 10 Multiple myeloma· 10 Cancer (any)· 10 Solid tumor· 10 Breast cancer· 9 Myelodysplastic syndromes (MDS)· 9 Non-Hodgkin lymphoma· 6 Ovarian cancer· 5 Myelofibrosis· 5 Head and neck cancer· 5 Gastric cancer· 4 Endometrial cancer· 4 Chronic lymphocytic leukemia (CLL)· 4 Hematologic malignancy· 4 Lung cancer· 3 Colorectal cancer· 3 Pancreatic cancer· 3 Brain metastases· 3 Leukemia (other)· 3 Myeloproliferative neoplasm· 3 Diffuse large B-cell lymphoma (DLBCL)· 3 Melanoma· 3 Triple-negative breast cancer· 2 Esophageal cancer· 2 Gastroesophageal junction cancer· 2 Prostate cancer· 2 Kidney cancer· 2 Cervical cancer· 2 Fallopian tube cancer· 2 Glioblastoma· 2 Glioma· 2 Mantle cell lymphoma· 2 Small lymphocytic lymphoma· 2 Sarcoma· 2 Osteosarcoma· 2 Neuroblastoma· 2 Metastatic breast cancer· 1 HER2-positive breast cancer· 1 HER2-negative breast cancer· 1 Colon cancer· 1 Rectal cancer· 1 Liver cancer· 1 Biliary tract cancer· 1 Bladder cancer· 1 Brain cancer· 1 Acute lymphoblastic leukemia· 1 Hodgkin lymphoma· 1 Follicular lymphoma· 1 Marginal zone lymphoma· 1 Pediatric cancer· 1 Neuroendocrine tumors· 1