Oncology Clinical Trials in Winston-Salem, NC
As of August 2026, 102 paid clinical trials are recruiting for Oncology in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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102 clinical trials for Oncology
·Clear filters·A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care Treatments
IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
REMASTer: REcurrent Brain Metastases After SRS Trial
Personalized Exercise Program for Survivors of Breast Cancer, STEPS-BC Trial
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Top Research Study Locations in Winston-Salem
Researchers run research studies in Winston-Salem, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Wake Forest University Health Sciences | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy | 160 |
| Atrium Health Wake Forest Baptist | Aging, Chronic Lymphocytic Leukemia, Myelofibrosis | 48 |
| Wake Forest University | Heart Failure, Heart Failure With Preserved Ejection Fraction, ALS-Frontotemporal Dementia | 23 |
| Novant Health Forsyth Medical Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer | 20 |
| Atrium Health Wake Forest Baptist Comprehensive Cancer Center | Acute Myeloid Leukemia, Cancer, Leukemia, Myeloid, Acute | 19 |
| Wake Forest Baptist Comprehensive Cancer Center | Malignant Solid Neoplasm, Nonsmall Cell Lung Cancer Stage III, Angiosarcoma | 19 |
| Atrium Health Wake Forest Baptist Medical Center | Acute Decompensated Heart Failure, Amyotrophic Lateral Sclerosis, Back Pain | 17 |
| Wake Forest Baptist Medical Center | Acute Respiratory Failure, Alzheimer Disease, Atrial Fibrillation | 14 |
| Wake Forest Baptist Health | Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, Alzheimer's Disease | 11 |
| Wake Forest University School of Medicine | AHRF, ARDS (Moderate or Severe), Acute Kidney Injury (AKI) | 10 |
| Wake Forest School of Medicine | Lung Diseases, Acute Respiratory Failure, Bone Loss | 7 |
| Wake Forest University Baptist Medical Center | Amputation, Antibiotic Side Effect, Aortic Stenosis | 6 |
| Southeastern Research Center | Idiopathic Pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis | 6 |
| Wake Forest NCORP Research Base | Breast Carcinoma, Cancer, Colorectal Carcinoma | 6 |
| GSK Investigational Site | Bronchiectasis, Irritable Bowel Syndrome, Multiple Myeloma | 5 |
| Novant Health Cancer Institute | Acute Myeloid Leukemia, in Relapse, MDS (Myelodysplastic Syndrome), Acute Myeloid Leukemia Refractory | 5 |
| Wake Forest | Acute Kidney Injury, Anesthesia, Anesthesia Awareness | 5 |
| Wake Forest Baptist | Focal Epilepsy, AAA - Abdominal Aortic Aneurysm, Community-acquired Pneumonia | 4 |
| Novant Health | Anemia, Benign Liver Tumor, Colorectal Cancer | 4 |
| Wake Forest Health Sciences | Albuminuria, Angiotensin Hypertension, Autonomic Dysfunction | 4 |
| Wake Forest University Health Sciences Department of Dermatology | Dermatologic Disease, ICD10 Code L40.9 for Psoriasis, Psoriasis | 3 |
| Brookview Hills Research Associates Llc | Antineutrophil Cytoplasmic Antibody-associated Vasculitis, Atherosclerotic Cardiovascular Disease, Obesity | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Atrium Health-Wake Forest Baptist | Chronic Pain, TEE Image Quality | 2 |
| Brookview Hills Research Associates, LLC | Diabetic Kidney Disease (DKD), Kidney Disease | 2 |
Active & Upcoming Studies in Winston-Salem (2026)
Recruiting trials in Winston-Salem grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (155 active studies)
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
- A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL) · Phase 1 · Wake Forest University Health Sciences
Neurology & pain (34 active studies)
- Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset Seizures · Phase 4 · Azurity Pharmaceuticals
- Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease · Phase 2 · Wake Forest University Health Sciences
Cardiovascular (30 active studies)
- Tailoring TM-HTN Intervention for Black Patients · Wake Forest University Health Sciences
- A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis · Phase 2 · Beijing Inno Medicine Co., Ltd.
Diabetes & metabolic (20 active studies)
- Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary Bypass · Wake Forest University Health Sciences
- Vibegron for ENergy Thinking and Resilience in Aging · Phase 3 · Wake Forest University Health Sciences
Mental health & behavior (12 active studies)
- Supporting Families in the ICU · Indiana University
- Enhancing Slow Wave Sleep in Depression · Wake Forest University Health Sciences
HIV / STI (7 active studies)
- Supporting Health and Empowerment Through Contingency Management and Affect Regulation · Wake Forest University Health Sciences
- Quitting Matters Human Immunodeficiency Virus Hybrid Trial · Wake Forest University Health Sciences
Pediatric (6 active studies)
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
- Comprehensive Care for AYA: Needs Assessment Survey · Wake Forest University Health Sciences
Eye & vision (4 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Vaccines (3 active studies)
Common conditions studied in Winston-Salem
- Acute Myeloid Leukemia (11 active studies)
- Multiple Myeloma (10 active studies)
- Cancer (9 active studies)
- Malignant Solid Neoplasm (7 active studies)
- Breast Cancer (5 active studies)
- Chronic Pain (5 active studies)
Leading research sponsors in Winston-Salem
- Wake Forest University Health Sciences
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- AbbVie
Frequently asked questions
How many paid clinical trials are currently recruiting in Winston-Salem?
There are approximately 527 recruiting clinical trials in Winston-Salem, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Winston-Salem pay participants?
Most recruiting trials in Winston-Salem compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Winston-Salem?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Winston-Salem?
The most common conditions under active study in Winston-Salem include Acute Myeloid Leukemia (11), Multiple Myeloma (10), Cancer (9), Malignant Solid Neoplasm (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Winston-Salem?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Winston-Salem on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Winston-Salem?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Winston-Salem?
Recruiting research sites in Winston-Salem include Wake Forest University Health Sciences, Atrium Health Wake Forest Baptist, Wake Forest University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Winston-Salem right now?
The largest active categories in Winston-Salem are Cancer & tumors (155), Neurology & pain (34), Cardiovascular (30). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.