Clinical Trials at Wake Forest University Health Sciences

As of July 2026, 150 paid clinical trials are recruiting at Wake Forest University Health Sciences, located at MEDICAL CENTER BLVD, WINSTON-SALEM, NC 27157-0001, phone (336) 716-2255 in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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150 clinical trials at Wake Forest University Health Sciences

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The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis

for Autoimmune Encephalitis

Drug: Inebilizumab

35 locations incl. Birmingham

Sponsor: University of Utah

Sex: All·Age: 12+

Code: NCT04372615·Phase 2·Recruiting

Apply to this trial

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

for Neuroblastoma

20 locations incl. Birmingham

Sponsor: Giselle Sholler

Sex: All·Age: 12 Months - 21

Code: NCT05489887·Phase 2·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for Astrocytoma, IDH-Mutant, Grade 2

43 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06860594·Phase 1·Recruiting

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Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

19 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting

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Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

43 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06287775·Phase 1, Phase 2·Recruiting

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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

69 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting

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RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

23 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting

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Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

for Lung Adenocarcinoma

34 locations incl. Buena Park

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05198830·Phase 2·Recruiting

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Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

for Locally Advanced Pancreatic Adenocarcinoma

Drug: Peposertib

44 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04172532·Phase 1, Phase 2·Recruiting

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A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

for Cardiovascular Disorder

31 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 7+

Code: NCT05705531·Recruiting

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

Apply to this trial

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

71 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting

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Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

for Acute Myeloid Leukemia

22 locations incl. New Haven

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06484062·Phase 1·Recruiting

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A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

for Acute Myeloid Leukemia

22 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 75

Code: NCT05886049·Phase 1·Recruiting

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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

for Metastatic Colorectal Carcinoma

60 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT05863195·Phase 3·Recruiting

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Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

for Recurrent Glioma

27 locations incl. Aurora

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05859334·Phase 2·Recruiting

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Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

for Recurrent Glioblastoma, IDH-Wildtype

Drug: Selinexor

36 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05432804·Phase 1, Phase 2·Recruiting

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Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for Recurrent Ovarian High Grade Serous Adenocarcinoma

27 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT04633239·Phase 1·Recruiting

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

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Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

for Neuropathy Ulnar

10 locations incl. Atlanta

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT04254185·Recruiting

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Enhancing Slow Wave Sleep in Depression

for Depression - Major Depressive Disorder

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 40 - 80

Code: NCT07143838·Recruiting

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BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching

for Heart Failure With Preserved Ejection Fraction

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 55+

Code: NCT07413198·Recruiting

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Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms

for Gastroparesis

5 locations incl. Scottsdale

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT04661215·Recruiting

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Telehealth and Remote Blood Pressure

for Hypertension

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 45

Code: NCT07356518·Recruiting

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Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity

for Uncontrolled Hypertension

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07031739·Recruiting

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Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial

for Anterior Cruciate Ligament Injuries

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 14 - 39

Code: NCT06942754·Recruiting

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Culturally Tailored Program for Food-Insecure Adults: SPICE-D

for Type 2 Diabetes Mellitus (T2D)

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07361341·Recruiting

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Identifying and Treating Depression in the Orthopaedic Trauma Population

for Depression

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05976347·Phase 4·Recruiting

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Evaluation of Flexible Conductive Hearing Aids

for Conductive Hearing Loss

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 6 Months - 80·Accepts healthy volunteers

Code: NCT07222202·Recruiting

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Bump the Lump - Intervention for the Treatment of Globus Pharyngeus

for Globus Pharyngeus

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06762444·Recruiting

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Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health

for Food Insecurity

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06942598·Recruiting

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Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

for Traumatic Brain Injury

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06866691·Phase 4·Recruiting

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Evaluating the Effect of Surgical Drain Securement on Patient Quality of Life and Postoperative Drain-related Complications

for Surgical Drain

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06916286·Recruiting

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Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy

for Myotonic Dystrophy

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07362875·Recruiting

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Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study

for Alcohol Use Disorder

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT06770556·Recruiting

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Validation of Chronic Obstructive Pulmonary Disease (COPD) Algorithm

for COPD (Chronic Obstructive Pulmonary Disease)

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 40+

Code: NCT07223749·Recruiting

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Remote Hypertension Management for Black Patients

for Uncontrolled Hypertension

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 21 - 85

Code: NCT06527794·Recruiting

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Pediatric and Caregiver Traumatic Stress Intervention (PACTS)

for Traumatic Injury

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 1 - 6

Code: NCT06366282·Recruiting

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Enhancing Physical Function in Older Adults With Chronic Kidney Disease

for Chronic Kidney Diseases

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 65 - 100

Code: NCT06738394·Recruiting

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Efficacy of 3D-Printed Mouth Splints

for Microstomia

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 2 - 99

Code: NCT06801535·Recruiting

Apply to this trial