Bevacizumab Plus Fluorouracil and Leucovorin in Treating Patients With Locally Advanced or Metastatic Stage IV Colorectal Cancer That Has Progressed After Standard Chemotherapy

Part of paid clinical trials in Anchorage, Alaska.

Sponsor
National Cancer Institute (NCI)
Study ID
NCT00066846
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • bevacizumab — BIOLOGICAL
  • fluorouracil — DRUG
  • leucovorin calcium — DRUG

Study Details

RATIONALE: Bevacizumab may stop the growth of tumor cells by blocking the enzymes necessary for cancer cell growth. Drugs used in chemotherapy such as fluorouracil and leucovorin use different ways to stop tumor cells from dividing so they stop growing or die. Combining bevacizumab with fluorouracil and leucovorin may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining bevacizumab with fluorouracil and leucovorin in treating patients who have locally advanced or metastatic stage IV colorectal cancer that has progressed after standard chemotherapy.

Key Dates

First listed
Aug 7, 2003
Start date
Aug 31, 2003
Status verified
Apr 2004
Completion
Jul 31, 2007

Study Design

Primary purpose
TREATMENT

Locations (33)

FacilityCityStateZIPSite coordinators
Providence Alaska Medical CenterAnchorageAlaska99519-6604-
Jonsson Comprehensive Cancer Center, UCLALos AngelesCalifornia90024-
USC/Norris Comprehensive Cancer Center and HospitalLos AngelesCalifornia90033-0804-
University of Colorado Cancer Center at University of Colorado Health Sciences CenterAuroraColorado80010-
Yale Comprehensive Cancer CenterNew HavenConnecticut06520-8028-
Lombardi Cancer CenterWashington D.C.District of Columbia20007-
CCOP - Atlanta RegionalAtlantaGeorgia30342-1701-
Robert H. Lurie Comprehensive Cancer Center, Northwestern UniversityChicagoIllinois60611-
Loyola University Medical CenterMaywoodIllinois60153-
Holden Comprehensive Cancer CenterIowa CityIowa52242-1009-
Siouxland Hematology-OncologySioux CityIowa51101-1733-
CCOP - WichitaWichitaKansas67214-3882-
Cancer Care of MaineBangorMaine04401-
Saint Joseph Mercy Health SystemAnn ArborMichigan48106-
St. Mary's/Duluth Clinic Cancer CenterDuluthMinnesota55805-
University of Mississippi Medical CenterJacksonMississippi39216-4505-
CCOP - Montana Cancer ConsortiumBillingsMontana59101-
Southern Nevada Cancer Research FoundationLas VegasNevada89106-
Norris Cotton Cancer CenterLebanonNew Hampshire03756-0002-
Roswell Park Cancer InstituteBuffaloNew York14263-0001-
New York Weill Cornell Cancer Center at Cornell UniversityNew YorkNew York10021-
Duke Comprehensive Cancer CenterDurhamNorth Carolina27710-
Comprehensive Cancer Center at Wake Forest UniversityWinston-SalemNorth Carolina27157-1082-
Meritcare Roger Maris Cancer CenterFargoNorth Dakota58122-
Ireland Cancer CenterClevelandOhio44106-5065-
University of Oklahoma Health Sciences CenterOklahoma CityOklahoma73104-
Abramson Cancer Center of the University of PennsylvaniaPhiladelphiaPennsylvania19104-
Kimmel Cancer Center of Thomas Jefferson University - PhiladelphiaPhiladelphiaPennsylvania19107-5541-
Sioux Valley Clinics - OncologySioux FallsSouth Dakota57104-
Fletcher Allen Health Care - University Health Center CampusBurlingtonVermont05401-
Massey Cancer CenterRichmondVirginia23298-0037-
CCOP - Virginia Mason Research CenterSeattleWashington98101-
Seattle Cancer Care AllianceSeattleWashington98109-

Find similar trials in Anchorage, AK

By condition
Colorectal cancer
By specialty
OncologyGI oncology
By research site
Providence Alaska Medical Center· Anchorage, AKJonsson Comprehensive Cancer Center, UCLA· Los Angeles, CAUSC/Norris Comprehensive Cancer Center and Hospital· Los Angeles, CAUniversity of Colorado Cancer Center at University of Colorado Health Sciences Center· Aurora, COYale Comprehensive Cancer Center· New Haven, CTLombardi Cancer Center· Washington D.C., DC

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