EXTEND III - Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)
- Sponsor
- Novartis
- Study ID
- NCT00470678
- Phase
- PHASE3
- Status
- Completed
Conditions
- Age-Related Macular Degeneration
- Choroidal Neovascularization
Eligibility Criteria
- Sex
- ALL
- Age
- 50 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- ranibizumab — DRUG
Study Details
This study will evaluate efficacy and safety for monthly ranibizumab 0.5 mg intravitreal injections in Asian patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration.
Key Dates
- First listed
- May 8, 2007
- Start date
- Jun 30, 2007
- Status verified
- Nov 2016
- Primary completion
- Nov 30, 2008
- Completion
- Nov 30, 2008
Study Design
- Enrollment
- 95 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: 1Ranibizumab
Primary Outcome Measure
Mean change in best-corrected visual acuity (BCVA) from Baseline, Month 4 and Month 12 as assessed with ETDRS (Early Treatment for Diabetic Retinopathy Study)-like charts at a distance of four meters [ Time Frame: Baseline, Month 4 and Month 12 ]
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