Age-related macular degeneration Clinical Trials

Recruiting age-related macular degeneration studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat age-related macular degeneration. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting age-related macular degeneration studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting age-related macular degeneration trials

Within

Non-invasive Ultrasound Retinal Stimulation for Vision Restoration

for Age-Related Macular Degeneration

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT05914233

Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension

for Age-Related Macular Degeneration

1 site in Los Angeles

Sponsor: Stanford University

Sex: All·Age: 55 - 75·Accepts healthy volunteers

Code: NCT07605468

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for Macular Degeneration

48 sites incl. Gilbert

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07496567·Phase 2, Phase 3

Apply to this trial

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

for Macular Degeneration

51 sites incl. Scottsdale

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07440225·Phase 2, Phase 3

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User-centric Study of Patients' Receptiveness Towards the Web-based Automated Vision Impairment Gaze-tracking Analysis Systems

for Age-Related Macular Degeneration

Sponsor: Tan Tock Seng Hospital

Sex: All·Age: 55 - 99

Code: NCT07338513

Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression

for Age-Related Macular Degeneration

Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Sex: All·Age: 50 - 85

Code: NCT05465252

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Preparation of Patient Autologous Induced Pluripotent Stem Cell-derived Retinal Cells for AMD

for Age-Related Macular Degeneration

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 55 - 80

Code: NCT05991986

AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance

for Age-Related Macular Degeneration

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 50 - 89·Accepts healthy volunteers

Code: NCT06619405

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Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

for Geographic Atrophy

5 sites incl. Carmel

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT07160179·Phase 1, Phase 2

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Safety of BBC1501 Intravitreal Injection in Patients With Neovascular Age-Related Macular Degeneration (nAMD)

for Age-Related Macular Degeneration

Sponsor: Benobio Co., Ltd.

Sex: All·Age: 50+

Code: NCT05803785·Phase 1

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Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study

for Age-Related Macular Degeneration

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 55+

Code: NCT07556406

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The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

for Alcohol Use Disorder

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06319872·Phase 1

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Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)

for Age-Related Macular Degeneration

7 sites incl. Fargo

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06924021

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Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

for Age-Related Macular Degeneration

5 sites incl. Manchester

Sponsor: i-Lumen Scientific AUS PTY LTD

Sex: All·Age: 60+

Code: NCT06662162

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The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma

for Age-Related Macular Degeneration

1 site in Worcester

Sponsor: MCPHS University

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT06593405·EARLY_Phase 1

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Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression

for Age-Related Macular Degeneration

Sponsor: Medical University of Vienna

Sex: All·Age: 55 - 99

Code: NCT06351657

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Visual Frailty in Ageing

for Frailty

Sponsor: University of Edinburgh

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06604104

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Adjunct Episcleral Brachytherapy for PCV

for Age-Related Macular Degeneration

Sponsor: Salutaris Medical Devices, Inc.

Sex: All·Age: 50+

Code: NCT05251636·Phase 3

Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression

for Age-Related Macular Degeneration

Sponsor: Medical University of Vienna

Sex: All·Age: 55 - 99

Code: NCT06351670

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Defining Retinal Structures Using Hyperspectral Retinal Imaging

for Age-Related Macular Degeneration

Sponsor: Center for Eye Research Australia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07555574

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Evaluation of Clinical Progression, Prognostic Factors, and Quality of Life in Patients with Age-related Macular Degeneration.

for Age-Related Macular Degeneration

Sponsor: University of Udine

Sex: All·Age: 50 - 120

Code: NCT06899360

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Personalized Shared Eye-care Identification of Age-related Macular Degeneration Using Artificial Intelligence and Telemedicine by Matching Optometrist Office-based Sites With Clinical Supervision

for Age-Related Macular Degeneration

Sponsor: Medical University of Vienna

Sex: All·Age: 55 - 99·Accepts healthy volunteers

Code: NCT06465212

Impact of Age-related Macular Degeneration on Daily Living Activitie

for Age-Related Macular Degeneration

Sponsor: Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06333873

Safety and Tolerability of KH658 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

for Age-related Macular Degeneration

Sponsor: Chengdu Origen Biotechnology Co., Ltd.

Sex: All·Age: 50 - 85

Code: NCT06458595·Phase 1, Phase 2

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Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - SUMMIT (Part 2)

for Age-Related Macular Degeneration

Sponsor: University of Southampton

Sex: All·Age: All ages

Code: NCT06682455

Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.

for Retinal Disease

Sponsor: Eyestem Research Pvt. Ltd.

Sex: All·Age: 50 - 100

Code: NCT06394232·Phase 1, Phase 2

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Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

for Vision Impairment and Blindness

Sponsor: University of Copenhagen

Sex: All·Age: 70+·Accepts healthy volunteers

Code: NCT07015034

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Effects of Goji vs. Fiber on Macular Degeneration

for Age-Related Macular Degeneration

1 site in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 65 - 95·Accepts healthy volunteers

Code: NCT06237127

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Multicenter Real-life Observational Study Switched Aflibercept or Ranibizumab to Faricimab in Patients With AMD.

for Age-related Macular Degeneration

Sponsor: Nantes University Hospital

Sex: All·Age: 18+

Code: NCT06271330

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Lutein, Zeaxathin, and Fish Oil Supplementation

for Cognitive Performance

1 site in College Station

Sponsor: Texas A&M University

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06489873

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Progression of Early Atrophic Lesions

for Age-Related Macular Degeneration

1 site in Salt Lake City

Sponsor: University of Utah

Sex: All·Age: 50+

Code: NCT05959005

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Direct Discrimination of Quantum States by the Human Eye

for Age-Related Macular Degeneration

Sponsor: Centre for Eye and Vision Research

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05913063

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Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

for Age-Related Macular Degeneration

7 sites incl. Scottsdale

Sponsor: Perceive Biotherapeutics, Inc.

Sex: All·Age: 60+

Code: NCT06087458·Phase 1, Phase 2

Apply to this trial

Expressive Arts-based Intervention for Adults With Age-related Visual Impairment

for Age-Related Macular Degeneration

Sponsor: The University of Hong Kong

Sex: All·Age: 50 - 80

Code: NCT05675150

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Photobiomodulation in Dry Age Related Macular Degeneration

for Age-Related Macular Degeneration

Sponsor: Azienda Ospedaliera Universitaria Mater Domini, Catanzaro

Sex: All·Age: 50+

Code: NCT06046118

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Safety and Tolerability of KH631 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

for Age-Related Macular Degeneration

Sponsor: Chengdu Origen Biotechnology Co., Ltd.

Sex: All·Age: 50 - 85

Code: NCT05672121·Phase 1, Phase 2

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Photobiomodulation for Dry Age Related Macula Degeneration

for Photobiomodulation

Sponsor: Oslo University Hospital

Sex: All·Age: 50+

Code: NCT05507840

Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular Degeneration

for AMD

Sponsor: VisionCare, Inc.

Sex: All·Age: 55+

Code: NCT04796545

Apply to this trial

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

for Age-Related Macular Degeneration

10 sites incl. Loma Linda

Sponsor: VisionCare, Inc.

Sex: All·Age: 65+

Code: NCT05438732

Apply to this trial

Visual Remapping to Aid Reading With Field Loss

for Age-related Macular Degeneration

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT03848663

Apply to this trial

Adaptive Optics Imaging of Outer Retinal Diseases

for Retinal Degeneration

2 sites incl. Bethesda

Sponsor: Food and Drug Administration (FDA)

Sex: All·Age: 21+

Code: NCT05355415

Apply to this trial

Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD

for Age-related Macular Degeneration

1 site in Boston

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: 50 - 85

Code: NCT04735263·Phase 2

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Project AMD: Comprehensive Characterisation of Age-Related Macular Degeneration and Its Progression

for Age Related Macular Degeneration

Sponsor: Center for Eye Research Australia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04739319

Apply to this trial

Village-Integrated Eye Worker Trial II

for Age-related Macular Degeneration

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT03752840

Apply to this trial

A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration

for Age-Related Macular Degeneration

12 sites incl. Los Angeles

Sponsor: Astellas Institute for Regenerative Medicine

Sex: All·Age: 50+

Code: NCT03178149·Phase 1

Apply to this trial

Stem Cell Ophthalmology Treatment Study II

for Retinal Disease

2 sites incl. Westport

Sponsor: MD Stem Cells

Sex: All·Age: 18+

Code: NCT03011541

Apply to this trial

High Resolution Retinal Imaging

for Stargardts

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT01866371

Apply to this trial

National Eye Institute Biorepository for Retinal Diseases

for Age-Related Macular Degeneration

1 site in Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 2 - 120·Accepts healthy volunteers

Code: NCT01496625

Apply to this trial

Age-related macular degeneration clinical trials — common questions

Are age-related macular degeneration clinical trials free to join?

Yes. Participating in a age-related macular degeneration clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a age-related macular degeneration clinical trial?

Each age-related macular degeneration study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a age-related macular degeneration trial near me?

Use the location controls above. We'll show recruiting age-related macular degeneration trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many age-related macular degeneration trials are recruiting right now?

We're currently tracking roughly 20 recruiting age-related macular degeneration trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Age-related macular degeneration trials by city

Los Angeles, CA San Francisco, CA Boston, MA Carmel, IN Loma Linda, CA Sacramento, CA Salt Lake City, UT Worcester, MA

Related specialties

Ophthalmology Retina