Retina Clinical Trials

Recruiting retina studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat retina. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting retina studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting retina trials

Within

Non-invasive Ultrasound Retinal Stimulation for Vision Restoration

for Age-Related Macular Degeneration

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT05914233

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)

for Diabetic Retinopathy

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07705607·Phase 3

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)

for Diabetic Retinopathy

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07705555·Phase 3

Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes

for Diabetic Retinopathy

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 22+

Code: NCT06763952

Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension

for Age-Related Macular Degeneration

1 site in Los Angeles

Sponsor: Stanford University

Sex: All·Age: 55 - 75·Accepts healthy volunteers

Code: NCT07605468

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy

for Diabetic Retinopathy

1 site in Glendale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07588100·Phase 1

Apply to this trial

Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

for Diabetic Retinopathy

14 sites incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07592273·Phase 2, Phase 3

Apply to this trial

Community-Based Eye Screening With Structured Referral Tracking for Preventing Avoidable Blindness in Adults in Rawalpindi, Pakistan

for Cataract

Sponsor: Health Services Academy, Islamabad, Pakistan

Sex: All·Age: 18+

Code: NCT07611682

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for Macular Degeneration

48 sites incl. Gilbert

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07496567·Phase 2, Phase 3

Apply to this trial

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

for Macular Degeneration

51 sites incl. Scottsdale

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07440225·Phase 2, Phase 3

Apply to this trial

Strategies for Improving Linkage-to-Care After Eye Disease Screening

for Age Related Macular Degeneration

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 60+

Code: NCT06943599

Apply to this trial

Wide Field OCTA in Ocular Diseases

for Age - Related Macular Degeneration (AMD)

Sponsor: IRCCS San Raffaele

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07298174

User-centric Study of Patients' Receptiveness Towards the Web-based Automated Vision Impairment Gaze-tracking Analysis Systems

for Age-Related Macular Degeneration

Sponsor: Tan Tock Seng Hospital

Sex: All·Age: 55 - 99

Code: NCT07338513

High Resolution Imaging OCT Study

for Normal Eyes

Sponsor: Heidelberg Engineering GmbH

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07338461

Multicenter RCT of Eye-Brain Imaging in Diabetes Neurovascular Coupling

for Diabetes Mellitus

Sponsor: Hejiang Ye

Sex: All·Age: 18 - 70

Code: NCT06813274·Phase 2

A Preliminary Exploratory Clinical Trial to Evaluate the Efficacy of NPDR-01 Eye Drops in the Treatment of Non-Proliferative Diabetic Retinopathy

for Non-proliferative Diabetic Retinopathy (NPDR)

Sponsor: Sichuan Academy of Medical Sciences

Sex: All·Age: 35 - 75

Code: NCT07198815·EARLY_Phase 1

Longitudinal Observational Study of Diabetic Retinopathy Progression in Type 2 Diabetes Patients

for Diabetic Retinopathy

Sponsor: Association for Innovation and Biomedical Research on Light and Image

Sex: All·Age: 35 - 80

Code: NCT07458516

Apply to this trial

Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium

for Retinopathy

1 site in Ann Arbor

Sponsor: MediBeacon

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04008121·EARLY_Phase 1

Apply to this trial

Analysis of DR Progression to Identify Risks and Need for Treatment

for Diabetic Retinopathy

Sponsor: Association for Innovation and Biomedical Research on Light and Image

Sex: All·Age: 35 - 90

Code: NCT07417410

Apply to this trial

Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression

for Age-Related Macular Degeneration

Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Sex: All·Age: 50 - 85

Code: NCT05465252

Apply to this trial

Preparation of Patient Autologous Induced Pluripotent Stem Cell-derived Retinal Cells for AMD

for Age-Related Macular Degeneration

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 55 - 80

Code: NCT05991986

AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance

for Age-Related Macular Degeneration

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 50 - 89·Accepts healthy volunteers

Code: NCT06619405

Apply to this trial

Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

for Geographic Atrophy

5 sites incl. Carmel

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT07160179·Phase 1, Phase 2

Apply to this trial

Investigating the Retardation Effect of OCTA-Guided Targeted Photocoagulation on the Progression of Non-Perfusion Areas in Diabetic Retinopathy Patients

for Diabetic Retinopathy

Sponsor: Sichuan Provincial People's Hospital

Sex: All·Age: 18+

Code: NCT06821633

Safety of BBC1501 Intravitreal Injection in Patients With Neovascular Age-Related Macular Degeneration (nAMD)

for Age-Related Macular Degeneration

Sponsor: Benobio Co., Ltd.

Sex: All·Age: 50+

Code: NCT05803785·Phase 1

Apply to this trial

Performance of the Electroretinogram, Performed and Interpreted by an Advanced Practice Nurse, in the Screening for Diabetic Retinopathy.

for Diabetic Retinopathy

Sponsor: CHU de Reims

Sex: All·Age: 18+

Code: NCT06782997

Apply to this trial

Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study

for Age-Related Macular Degeneration

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 55+

Code: NCT07556406

Apply to this trial

Retinal Investigation Using Optos OCT Device

for AMD - Age-Related Macular Degeneration

Sponsor: Optos, PLC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06846151

An Interpretable Fundus Diseases Report Generating System Based On Weakly Labelings

for Retinal Diseases

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06918028

Video-based Patient Education Intervention for Diabetic Eye Screening in Latinx Communities

for Diabetic Retinopathy

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06257082

Apply to this trial

The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

for Alcohol Use Disorder

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06319872·Phase 1

Apply to this trial

Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)

for Age-Related Macular Degeneration

7 sites incl. Fargo

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06924021

Apply to this trial

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

for Age-Related Macular Degeneration

5 sites incl. Manchester

Sponsor: i-Lumen Scientific AUS PTY LTD

Sex: All·Age: 60+

Code: NCT06662162

Apply to this trial

Effect of Video Viewing on Intravitreal Injection Experience

for Age Related Macular Degeneration

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Sex: All·Age: 18+

Code: NCT07002372

Apply to this trial

The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma

for Age-Related Macular Degeneration

1 site in Worcester

Sponsor: MCPHS University

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT06593405·EARLY_Phase 1

Apply to this trial

Remote Ischemic Conditioning for Non-Proliferative Diabetic Retinopathy

for Diabetic Retinopathy

Sponsor: Xuxiang Zhang, MD

Sex: All·Age: 40 - 80

Code: NCT06713720

Apply to this trial

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression

for Age-Related Macular Degeneration

Sponsor: Medical University of Vienna

Sex: All·Age: 55 - 99

Code: NCT06351657

Apply to this trial

Visual Frailty in Ageing

for Frailty

Sponsor: University of Edinburgh

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06604104

Apply to this trial

Adjunct Episcleral Brachytherapy for PCV

for Age-Related Macular Degeneration

Sponsor: Salutaris Medical Devices, Inc.

Sex: All·Age: 50+

Code: NCT05251636·Phase 3

AI-Powered DIY Screening System for Diabetic Retinopathy

for Diabetic Retinopathy

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06892353

Apply to this trial

Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression

for Age-Related Macular Degeneration

Sponsor: Medical University of Vienna

Sex: All·Age: 55 - 99

Code: NCT06351670

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01

for Diabetic Retinopathy

8 sites incl. Beverly Hills

Sponsor: Vantage Biosciences Ltd

Sex: All·Age: 18+

Code: NCT06770933·Phase 2

Apply to this trial

Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus

for Diabetes

Sponsor: Yufan Wang

Sex: All·Age: 20 - 79

Code: NCT06821399

Apply to this trial

Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy

for Proliferative Diabetic Retinopathy

Sponsor: Vastra Gotaland Region

Sex: All·Age: 18+

Code: NCT06549023

Apply to this trial

Prospective Cohort Study on Predicting the Progression of Diabetic Microangiopathy Using Multimodal Eye Imaging

for Diabetic Retinopathy

Sponsor: Peking University Third Hospital

Sex: All·Age: 40 - 80

Code: NCT06727955

Pivotal Trial of Automated Artificial Intelligence (AI) Based System for Early Diagnosis of Diabetic Retinopathy

for Diabetes

1 site in Richmond Hill

Sponsor: iHealthScreen Inc

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07151001

Apply to this trial

Defining Retinal Structures Using Hyperspectral Retinal Imaging

for Age-Related Macular Degeneration

Sponsor: Center for Eye Research Australia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07555574

Apply to this trial

A Study Intravitreal THN391 in Diabetic Macular Oedema Secondary to Non-Proliferative Diabetic Retinopathy.

for Diabetic Macular Edema

Sponsor: Therini Bio Pty Ltd

Sex: All·Age: 18 - 80

Code: NCT06701721·Phase 1

Apply to this trial

Is Community Based Monitoring of Diabetic Maculopathy and Pre-proliferative Diabetic Retinopathy Safe?

for Diabetes Mellitus

Sponsor: Hywel Dda Health Board

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06955611

Apply to this trial

Evaluating a New Peptide Therapy for Retinal Diseases: AMD, Diabetic Retinopathy, and Dystrophies

for Retinitis Pigmentosa (RP)

Sponsor: Ace Cells Lab Limited

Sex: All·Age: All ages

Code: NCT06787482·Phase 1, Phase 2

Apply to this trial

Assessing of Artificial Intelligence-based Software Platform for Diabetic Retinopathy Screening

for Diabetic Retinopathy

Sponsor: The Filatov Institute of Eye Diseases and Tissue Therapy

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06879834

Apply to this trial

Clinical Trial of Keluoxin Capsules in the Treatment of Diabetic Kidney Disease with Diabetic Retinopathy

for Diabetic Kidney Disease

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18 - 75

Code: NCT06660940·Phase 4

Evaluation of Clinical Progression, Prognostic Factors, and Quality of Life in Patients with Age-related Macular Degeneration.

for Age-Related Macular Degeneration

Sponsor: University of Udine

Sex: All·Age: 50 - 120

Code: NCT06899360

Apply to this trial

Glaucoma Algorithm Validation Study in African Population - the MAGIC Study

for Glaucoma

Sponsor: Centro Hospitalar Universitário Lisboa Norte

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06552247

Artificial Intelligence for Diagnosing Diabetic Retinopathy in Primary Care

for Diabetic Retinopathy

Sponsor: Hospital de Clinicas de Porto Alegre

Sex: All·Age: 18+

Code: NCT07236879

Apply to this trial

Personalized Shared Eye-care Identification of Age-related Macular Degeneration Using Artificial Intelligence and Telemedicine by Matching Optometrist Office-based Sites With Clinical Supervision

for Age-Related Macular Degeneration

Sponsor: Medical University of Vienna

Sex: All·Age: 55 - 99·Accepts healthy volunteers

Code: NCT06465212

Single-Cell Insights Into Diabetic Retinopathy Mechanisms

for Diabetic Retinopathy

Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Sex: All·Age: 18+

Code: NCT06497608

Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy

for Diabetic Retinopathy

1 site in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT06191094·Phase 4

Comparing Artificial Intelligence for Assisted Diagnosis of Diabetic Retinopathy

for Diabetic Retinopathy

Sponsor: Zhejiang University

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06423274

Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage

for Diabetic Retinopathy

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 40 - 90

Code: NCT06272565

Retina clinical trials — common questions

Are retina clinical trials free to join?

Yes. Participating in a retina clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a retina clinical trial?

Each retina study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a retina trial near me?

Use the location controls above. We'll show recruiting retina trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many retina trials are recruiting right now?

We're currently tracking roughly 41 recruiting retina trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Retina trials by city

Madison, WI San Francisco, CA Birmingham, AL Carmel, IN Los Angeles, CA Ann Arbor, MI Aurora, CO Beverly Hills, CA Boston, MA Chicago, IL Glendale, CA Loma Linda, CA

What to expect

Recruiting retina trials

Retina clinical trials — common questions

Retina trials by city

Conditions in this area