Comparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung Cancer

Conditions

• Lung Cancer

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• lobectomy — PROCEDURE
• segmentectomy or wedge resection — PROCEDURE

Study Details

RATIONALE: Wedge resection or segmentectomy may be less invasive types of surgery than lobectomy for non-small cell lung cancer and may have fewer side effects and improve recovery. It is not yet known whether wedge resection or segmentectomy are more effective than lobectomy in treating stage IA non-small cell lung cancer. PURPOSE: This randomized phase III trial is studying different types of surgery to compare how well they work in treating patients with stage IA non-small cell lung cancer.

Key Dates

Start date

Oct 12, 2007

Status verified

Jan 2026

Primary completion

Sep 30, 2025

Completion

Sep 30, 2025

Study Design

Enrollment

701 participants (actual)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Other: Arm A
  Patients undergo a standard operation for lung cancer called a lobectomy.
• Experimental: Arm B
  Patents undergo a limited resection (segentectomy or wedge resection), which a smaller portion of the lung is removed.

Primary Outcome Measure

disease-free survival [ Time Frame: Up to 7 years ]

Locations (373)

Find similar trials in Birmingham, AL

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