Evaluation of Efficacy and Safety of Dapagliflozin as Monotherapy in Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control With Diet and Exercise Alone
- Sponsor
- AstraZeneca
- Study ID
- NCT01257412
- Phase
- PHASE3
- Status
- Suspended
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 19 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Dapagliflozin — DRUG5mg Oral dose od
- Dapagliflozin — DRUG10 mg Oral dose od
- placebo — DRUG5/10 mg Oral dose od
Study Details
This study intends to compare the efficacy and safety of dapagliflozin versus placebo in treatment-naïve subjects with type 2 diabetes who have inadequate glycaemic control with diet and exercise alone.
Key Dates
- Start date
- Jan 31, 2012
- Status verified
- Feb 2012
- Primary completion
- Jun 30, 2013
- Completion
- Jun 30, 2013
Study Design
- Enrollment
- 375 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: 1
- Experimental: 2
- Placebo Comparator: 3
Primary Outcome Measure
change in glycosylated haemoglobin A1c (HbA1c). [ Time Frame: From baseline to week 24 ]
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