Type 2 diabetes Clinical Trials

Recruiting type 2 diabetes studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat type 2 diabetes. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting type 2 diabetes studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting type 2 diabetes trials

Within

MEDBRIDGE-Guided NCM/CHW Post-Discharge Support for High-Risk T2D Patients

for Type 2 Diabetes

2 sites in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07599852

South Asians With Type 2 Diabetes at Risk for Depression

for Type 2 Diabetes

1 site in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18 - 75

Code: NCT07219667

Integrating Care for Hypertension-Diabetes MULTImorbidity in Guatemala Through HEARTS Implementation

for Hypertension (HTN)

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07536919

The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM)

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: Universiti Teknologi Mara

Sex: All·Age: 18 - 65

Code: NCT07664501

Effects of Vibration-Assisted Physical Activity in Type-2 Diabetes

for Diabetes Mellitus, Type 2

Sponsor: University of Central Lancashire

Sex: All·Age: 18 - 65

Code: NCT07350473

Efficacy of the Use of Real-time Continuous Glucose Monitoring on Glycemic Control in Patients With Type 2 Diabetes and Stage 3 and 4 Chronic Kidney Disease.

for Type 2 Diabetes

Sponsor: Hospital Universitario San Ignacio

Sex: All·Age: 18+

Code: NCT07668219

Effect of Molar Replacement on Glycemic Control in Adults With Uncontrolled Type 2 Diabetes

for Type 2 Diabetes

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18 - 75

Code: NCT07666529

Phase II Study of Switching From Dulaglutide to PG-102(MG12) in Type 2 Diabetes Mellitus

for Type 2 Diabetes

Sponsor: ProGen. Co., Ltd.

Sex: All·Age: 19 - 75

Code: NCT07677891·Phase 2

"Effectiveness of Supervised and Unsupervised mHealth-based Exercise Interventions on Clinical Outcomes in Adults With Type 2 Diabetes and Obesity Within a Primary Care Context"

for Diabetes Mellitus, Type 2

Sponsor: Escuela Universitaria de Osuna

Sex: All·Age: 30 - 65

Code: NCT07685080

Effects of Whole Fruit on Blood Sugar in People With Type 2 Diabetes

for Type 2 Diabetes

1 site in Boston

Sponsor: Harvard School of Public Health (HSPH)

Sex: All·Age: 18+

Code: NCT07376226

BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: Carnot Laboratories

Sex: All·Age: 18+

Code: NCT07628985·Phase 3

PLEASURE (Pleasing Lovers, Efficacy, Arousal, Satisfaction, and Uptake Research on Eroxon)

for Type 2 Diabetes

1 site in Miami

Sponsor: University of Miami

Sex: Male·Age: 18 - 40

Code: NCT07636161·Phase 4

A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

for Diabetes Mellitus, Type 2

17 sites incl. Sacramento

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT07668336·Phase 3

Exocrine-Endocrine Pancreatic Crosstalk: Precision Pathways to Reframe Diabetes Pathophysiology

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 20 - 78

Code: NCT07670871

Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes

for Obesity

Sponsor: University Hospital, Toulouse

Sex: All·Age: 45 - 70·Accepts healthy volunteers

Code: NCT07075133

Efficacy and Safety of Mazdutide in Patients With Type 2 Diabetes Mellitus and Moderate to Severe Nonalcoholic Fatty Liver Disease Previously Treated With Semaglutide

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: Tianjin Medical University

Sex: All·Age: 18 - 60

Code: NCT07713992

Effect of Prebiotics in Saudi Adults With Type 2 Diabetes

for Type 2 Diabetes

Sponsor: Princess Nourah Bint Abdulrahman University

Sex: All·Age: 45 - 60·Accepts healthy volunteers

Code: NCT07464691

PLAY2CONTROL Study

for Type 2 Diabetes

1 site in Miami

Sponsor: University of Miami

Sex: All·Age: 5 - 21

Code: NCT07556679

RAndomized EHR-based Prescribing to Improve Disease-modifying Therapies for Cardio-Kidney-Metabolic Care (RAPID-CKM)

for Chronic Kidney Disease

2 sites incl. Dallas

Sponsor: Baylor Research Institute

Sex: All·Age: 18+

Code: NCT07605390

Influence of the Use of Specific Nutritional Formulas on Time in Range in Patients With Type 2 Diabetes

for Type 2 Diabetes

Sponsor: Hospital Universitario San Ignacio

Sex: All·Age: 18+

Code: NCT07666581

Co-designing Enhanced Models of Care for First Nations Children at Risk for Childhood-onset Type 2 Diabetes

for Type 2 Diabetes

Sponsor: University of Manitoba

Sex: All·Age: Up to 18·Accepts healthy volunteers

Code: NCT07692321

Durian Consumption in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes

Sponsor: Singapore General Hospital

Sex: All·Age: 21 - 70

Code: NCT07697612

Peer Support and Remote Patient Monitoring for Black Adults With Type 2 Diabetes

for Type 2 Diabetes

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 19+

Code: NCT07181304

Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Diet and Exercise Alone（UNIGUIDE-1）

for Type 2 Diabetes

Sponsor: The United Bio-Technology (Hengqin) Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07659574·Phase 3

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

for Diabetes Mellitus, Type 2

21 sites incl. New Haven

Sponsor: Novo Nordisk A/S

Sex: All·Age: 10 - 18

Code: NCT07282613·Phase 3

Exercise and Intranasal Insulin in Type 2 Diabetes

for Type 2 Diabetes

4 sites incl. New Brunswick

Sponsor: Rutgers, The State University of New Jersey

Sex: All·Age: 55 - 80

Code: NCT07675499·Phase 2, Phase 3

Apply to this trial

Remotely Delivered Mindfulness-Based Diabetes Education

for Type 2 Diabetes

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 19+

Code: NCT06312553

Effect of Interactive Video-Based Self-Management Education in Adults With Type 2 Diabetes

for Type 2 Diabetes

Sponsor: Abant Izzet Baysal University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07374744

DP-DCT 1.0：A Comparative Clinical Study on the Effect of Dapagliflozin Combined With CGM Versus SMBG on Glycemic Control in Patients With Type 2 Diabetes Mellitus Based on the DP-DCT Platform

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: The Third Xiangya Hospital of Central South University

Sex: All·Age: 18+

Code: NCT07595289

Point-of-care Capillary HbA1c Testing for Type 2 Diabetes Screening Among At-risk Individuals in Rural Dali, China

for Type 2 Diabetes

Sponsor: The University of Hong Kong

Sex: All·Age: 18+

Code: NCT07718867

Real-time Engagement for Learning to Effectively Control Type 2 Diabetes

for Diabetes Mellitus, Type 2

1 site in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 16 - 24

Code: NCT06375460

A Clinical Study to Evaluate the Effect of Different Dosing Conditions on the Pharmacokinetics of HRS9531 Tablets in Healthy Participants

for Weight Management

Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd.

Sex: Male·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06506175·Phase 1

Time Restricted Eating in Patients With Microalbuminuria

for Type 2 Diabetes Mellitus (T2DM)

1 site in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 75

Code: NCT06884059·Phase 1

Apply to this trial

Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study

for Type 2 Diabetes Mellitus

10 sites incl. Birmingham

Sponsor: Endogenex, Inc.

Sex: All·Age: 22+

Code: NCT07197788

Time-restricted Eating for Patients With Type 2 Diabetes

for Type 2 Diabetes

1 site in Lexington

Sponsor: Justin (Matt) Thomas

Sex: All·Age: 18+

Code: NCT07318207

Apply to this trial

SMART 2D: Study of Montelukast's Effects on Renal and Cardiovascular Health in Adolescents and Young Adults With Type 2 Diabetes

for Type 2 Diabetes

Sponsor: University of Colorado, Denver

Sex: All·Age: 14 - 24

Code: NCT07409714·EARLY_Phase 1

Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults

for Type 2 Diabetes

Sponsor: May Faraj, PDt, PhD

Sex: All·Age: 40 - 70·Accepts healthy volunteers

Code: NCT07575438·Phase 2

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting

for Diabetes Mellitus, Type 2

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 65

Code: NCT07613307·Phase 3

Closed Loop Glucose Control in a Simulated ICU Setting

for Type 1 Diabetes

Sponsor: Ideal Medical Technologies

Sex: All·Age: 18 - 70

Code: NCT07646067

Cooking Health-Oriented Meals to Prevent Dementia and Diabetes

for Type 2 Diabetes

Sponsor: Virginia Polytechnic Institute and State University

Sex: All·Age: 50 - 75·Accepts healthy volunteers

Code: NCT07661368

Cardiometabolic Impact of a Produce Prescription Program in Patients With Type 2 Diabetes and Food Insecurity

for Type 2 Diabetes

1 site in Morgantown

Sponsor: West Virginia University

Sex: All·Age: 18+

Code: NCT07674979

Free Fatty Acid Effects In Type 2 Diabetes

for Type 2 Diabetes

Sponsor: University of Ulster

Sex: All·Age: 18+

Code: NCT07677995

AI-Assisted Antidiabetic Drug Consultation System for Glycemic Control in Type 2 Diabetes Patients Managed by Non-Specialist Physicians

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: National Taiwan University Hospital

Sex: All·Age: 19 - 80

Code: NCT07684690

A Three-part First-in-human Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GUB-UCN2 in Healthy Lean and Obese Participants and Participants With T2D

for Obesity

Sponsor: Gubra A/S

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07702890·Phase 1, Phase 2

Preadmission GLP-1 Receptor Agonist Plus SGLT2 Inhibitor Use and Early Outcomes After Pneumonia Hospitalization in Adults With Type 2 Diabetes

for Pneumonia

Sponsor: Chung Shan Medical University

Sex: All·Age: 18+

Code: NCT07708610

Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2)

for Type 2 Diabetes

Sponsor: The United Bio-Technology (Hengqin) Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07653477·Phase 3

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

for Obesity

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07684144·Phase 3

Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay.

for Obesity

Sponsor: Las Rías Medical Center

Sex: All·Age: 18 - 70

Code: NCT07588438·Phase 4

Apply to this trial

AI-Assisted Lifestyle Intervention Versus Tirzepatide for Obesity and Newly Diagnosed Type 2 Diabetes

for Obesity

Sponsor: The First Affiliated Hospital of Anhui Medical University

Sex: All·Age: 18 - 65

Code: NCT07697391·Phase 4

Qatar Cardiometabolic Retrospective Cohort-Analysis Using Artificial Intelligence

for Cardio Vascular Disease

Sponsor: Weill Cornell Medical College in Qatar

Sex: All·Age: 18+

Code: NCT07515807

SALUD-M: Acceptance Based Coping Skills for Hispanic/Latinx Military Patients With Type 2 Diabetes

for Type 2 Diabetes

Sponsor: Baylor College of Medicine

Sex: All·Age: 18 - 70

Code: NCT07674628

Imaging in Semaglutide Study

for Type 2 Diabetes

1 site in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 45 - 75

Code: NCT07695454

Advancing Diabetes Management for People With Physical Disabilities Optimally Through Primary Care-Based Telehealth (ADDOPT)

for Type 2 Diabetes

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 89

Code: NCT07032844

A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or Overweight, With or Without Type 2 Diabetes

for Obesity

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07670416·Phase 3

Apply to this trial

Lactate and Glycerol Contribution to Gluconeogenesis

for Type 2 Diabetes

Sponsor: Rutgers, The State University of New Jersey

Sex: All·Age: 40 - 70·Accepts healthy volunteers

Code: NCT06955130

NOURISH - A Healthcare-community Partnership to Improve Nutrition for Optimal Glycemic Control and Pregnancy Outcomes With Pregestational Diabetes

for Type 2 Diabetes

1 site in Columbus

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT07560813

Finerenone for Regression of Albuminuria in Type 2 Diabetes With Chronic Kidney Disease

for Albuminuria

Sponsor: First Affiliated Hospital of Zhejiang University

Sex: All·Age: 18+

Code: NCT07667517·Phase 4

Salivary Apelin, Chemerin, Ghrelin, and Lipocalin-2 Levels in Diabetic Patients With Periodontitis

for Periodontitis

Sponsor: Necmettin Erbakan University

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07703345

Apply to this trial

Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT-2 Inhibitors

for Type 1 Diabetes

1 site in Orlando

Sponsor: AdventHealth Translational Research Institute

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07421518·Phase 2

Integrating New Skills Into Diabetes Education With CGM

for Insulin Dependent Diabetes

1 site in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 65+

Code: NCT07463209

Type 2 diabetes clinical trials — common questions

Are type 2 diabetes clinical trials free to join?

Yes. Participating in a type 2 diabetes clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a type 2 diabetes clinical trial?

Each type 2 diabetes study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a type 2 diabetes trial near me?

Use the location controls above. We'll show recruiting type 2 diabetes trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many type 2 diabetes trials are recruiting right now?

We're currently tracking roughly 231 recruiting type 2 diabetes trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Type 2 diabetes trials by city

Birmingham, AL Boston, MA Aurora, CO Chicago, IL Columbus, OH Los Angeles, CA San Diego, CA Ann Arbor, MI Milwaukee, WI Stanford, CA Miami, FL Omaha, NE

Related specialties

Endocrinology Metabolic health Weight loss