Repeated Eye Injections of Aflibercept for Treatment of Wet Age Related Macular Degeneration

Part of paid clinical trials in Cherry Hill, New Jersey.

Sponsor
MidAtlantic Retina
Study ID
NCT01773954
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

To evaluate the visual outcome and number of injections required during an optical coherence tomography (OCT)-guided treat and extend regimen with intravitreal aflibercept for treatment of subfoveal neovascular age-related macular degeneration (NVAMD).

Key Dates

Start date
Feb 28, 2013
Status verified
Apr 2018
Primary completion
Mar 31, 2016
Completion
Mar 31, 2016

Study Design

Enrollment
40 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Intravitreal Aflibercept Injection More
    Patient receives treatment at baseline and week 4 visit. The first time extension criteria are met the follow-up interval will be increased by 4 weeks. Each time the extension criteria is met the interval will be extended by 2 weeks to a maximum of 16 weeks. If a patient is being followed at an 8 week interval but fails to meet extension criteria at a particular visit, treatment will be administered as usual and the follow up interval will be reduced to 4 weeks. If patient is being followed at 10-16 week interval but fails to meet extension criteria at a particular visit, treatment will be administered but the follow-up interval will be reduced by 2 week increments.

Primary Outcome Measure

Mean Change in Best-corrected Early Treatment Diabetic Retinopathy Study (ETDRS) Letter Score [ Time Frame: Baseline to Week 52 ]

Locations (3)

FacilityCityStateZIPSite coordinators
Mid Atlantic Retina- Cherry HillCherry HillNew Jersey08002-
Mid Atlantic Retina- Huntingdon ValleyHuntingdon ValleyPennsylvania19006-
Mid Atlantic Retina- Wills Eye InstitutePhiladelphiaPennsylvania19107-

Find similar trials in Cherry Hill, NJ

By condition
Age-related macular degeneration
By specialty
OphthalmologyRetina
By research site
Mid Atlantic Retina- Cherry Hill· Cherry Hill, NJMid Atlantic Retina- Huntingdon Valley· Huntingdon Valley, PAMid Atlantic Retina- Wills Eye Institute· Philadelphia, PA

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