Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors

Part of paid clinical trials in Houston, Texas.

Sponsor: M.D. Anderson Cancer Center
Study ID: NCT02754544
Status: Recruiting

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Conditions

Brain Neoplasm
Metastatic Malignant Neoplasm in the Brain
Recurrent Brain Neoplasm

Eligibility Criteria

Sex: ALL
Age: 18 Years - N/A
Healthy Volunteers: Not accepted

Interventions

Direct Electrocortical Stimulation — PROCEDURE
Undergo direct electrocortical stimulation
Electrocorticography — OTHER
Undergo electrocorticography

Study Details

This pilot clinical trial studies how well electrocorticography works in mapping functional brain areas during surgery in patients with brain tumors. Using a larger than the standard mapping grid currently used during brain tumor surgery or a high-definition grid for electrocorticogram brain mapping may help doctors to better identify which areas of the brain are active during specific limb movement and speech during surgery in patients with brain tumors.

Key Dates

First listed: Apr 28, 2016
Start date: Jul 22, 2016
Status verified: May 2026
Primary completion: Jan 1, 2027
Completion: Jan 1, 2028

Study Design

Enrollment: 75 participants (estimated)
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Arms

Experimental: Diagnostic (electrocorticography)
Patients undergo tumor resection. During surgery, patients also undergo electrocorticography with either the CorTec high resolution hybrid grid, the PMT high-resolution grid, or the Ad-Tech grid followed by direct electrocortical stimulation.