Comparison of PDT Combination With Ranibizumab vs. Ranibizumab Monotherapy in Persistent PCV With Initial Loading Dose

Sponsor
Seoul National University Hospital
Study ID
NCT02864472
Phase
PHASE4
Status
Unknown

Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The aim of this study is to compare the efficacy of early intervention of PDT combination compared with consecutive monthly treatment of intravitreal ranibizumab injections in PCV patients showing insufficient response with initial loading dose.

Key Dates

First listed
Aug 12, 2016
Start date
Sep 30, 2016
Status verified
Aug 2016
Primary completion
Jun 30, 2018
Completion
Jan 31, 2019

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP

Arms

  • Other: combination Tx
    combination Tx(vPDT +ranibizumab) (M0) + ranibizumab PRN (M3-6)
  • Other: mono Tx
    Ranibizumab (at 4 weeks interval) \*3 (M0-2) + ranibizumab PRN (M3-6)

Primary Outcome Measure

Change in central retinal thickness [ Time Frame: after 6month ]

Central Contacts

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