Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT03256539
Status
Terminated

Conditions

Eligibility Criteria

Sex
ALL
Age
65 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Sleep intervention — BEHAVIORAL
    Behavioral sleep intervention program
  • Placebo intervention — BEHAVIORAL
    Quasi-desensitization intervention for insomnia (which does not include any of the active components of CBT-I but implemented in the same frequency and duration)

Study Details

This study aimed to pilot test a non-pharmacological (behavioral) treatment program targeting improved cognition through improving 24-h sleep-wake cycle in people with mild cognitive impairment (MCI) or mild Alzheimer's disease. A treatment program incorporating bright light therapy and a modified cognitive behavioral therapy for insomnia will be developed to address 24-hour patterns of sleep. We will then pilot test its feasibility and explore its preliminary effects on improving sleep/napping and cognition in patients with MCI or mild Alzheimer's disease.

Key Dates

Start date
Aug 12, 2021
Status verified
Oct 2025
Primary completion
Jan 31, 2024
Completion
Jan 31, 2024

Study Design

Enrollment
15 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Sleep Intervention
    Sleep treatment program (to be developed) that incorporates modified cognitive behavioral therapy for insomnia (CBT-I) and bright light therapy (BLT)
  • Placebo Comparator: Placebo intervention
    Placebo (quasi-desensitization) intervention for insomnia (which does not include any of the active components of CBT-I but implemented in the same frequency and duration).

Primary Outcome Measure

Number of Participants Enrolled to the Study [ Time Frame: Up to 24 weeks following study initiation ]

Locations (1)

FacilityCityStateZIPSite coordinators
UCSFSan FranciscoCalifornia94121-

Find similar trials in San Francisco, CA

By condition
Alzheimer's disease
By specialty
NeurologyDementia careBrain disordersGeriatrics
By research site
UCSF· San Francisco, CA

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