Alzheimer's disease Clinical Trials

Recruiting alzheimer's disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat alzheimer's disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting alzheimer's disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting alzheimer's disease trials

Within

Transcranial Magnetic Stimulation for Alzheimer's Disease Treatment

for Alzheimer Disease

Sponsor: Universitat Oberta de Catalunya

Sex: All·Age: 60 - 75

Code: NCT03121066

Vagus Nerve Stimulation to Enhance Memory in Aging

for Alzheimer Disease

1 site in Stanford

Sponsor: Stanford University

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07214194

Acupressure as Long-term Intervention to Slow the Progression of Early/Mild Alzheimer's Disease

for Alzheimer's Disease

Sponsor: The University of Hong Kong

Sex: All·Age: 60 - 85

Code: NCT07779863

Electroconvulsive Therapy for Treatment of Alzheimer´s Disease

for Alzheimer's Disease

Sponsor: Central Institute of Mental Health, Mannheim

Sex: All·Age: 65+

Code: NCT02438202

Tricaprilin Phase 3 ALTER-AD (Alternative-Alzheimer Disease) Study

for Alzheimer Disease

Sponsor: Cerecin

Sex: All·Age: 55 - 85

Code: NCT05809908·Phase 3

Repurposing a Combination Antiretroviral Drug Therapy to Target Retrotransposons and Treat Early Alzheimer's Disease

for Alzheimer's Disease

1 site in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 55 - 85

Code: NCT07795307·Phase 1

Cholinergic Deep Brain Stimulation for Alzheimer's Disease

for Alzheimer Disease, Early Onset

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 60 - 80

Code: NCT05882344

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

for Alzheimer's Disease

Sponsor: Hoffmann-La Roche

Sex: All·Age: 55 - 80

Code: NCT07717411·Phase 3

Alzheimer's Tau Platform: Regimen A - AADvac1

for Preclinical Alzheimer's Disease

1 site in San Francisco

Sponsor: Paul S. Aisen

Sex: All·Age: 50 - 80

Code: NCT07167966·Phase 2

Study of Intracerebroventricular Injections of Autologous Adipose-Derived Stem Cells (RB-ADSCs) in Participants With Mild-Moderate Alzheimer's Disease

for Alzheimer Disease

Sponsor: Regeneration Biomedical, Inc.

Sex: All·Age: 45 - 85

Code: NCT07205601·Phase 2

Study to Test Effects and Safety of RO7568282 in Early Symptomatic Alzheimer's Disease

for Alzheimer's Disease

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07781657·Phase 2

A Phase 2b/3 Clinical Study Evaluating T3D-959 in Mild-to-Moderate Alzheimer's Disease Subjects

for Alzheimer's Disease

1 site in Durham

Sponsor: T3D Therapeutics, Inc.

Sex: All·Age: 50 - 90

Code: NCT06964230·Phase 2, Phase 3

DUVAX: A Phase 1 Alzheimer's Vaccine Study Targeting Amyloid-Beta and Tau

for Alzheimer Disease

1 site in Miami Lakes

Sponsor: Nuravax, Inc.

Sex: All·Age: 40 - 65·Accepts healthy volunteers

Code: NCT07142278·Phase 1

The Care for America's Aging Study

for Cognitive Impairment

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06021704

Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin

for Alzheimer's Disease

1 site in Baltimore

Sponsor: National Institute on Aging (NIA)

Sex: All·Age: 65 - 120·Accepts healthy volunteers

Code: NCT07721467·Phase 2

Repeat Intracerebroventricular Injections of RB-ADSC in Subjects Previously Treated in RBI Protocol RB-ADSC-02

for Alzheimer Disease

Sponsor: Regeneration Biomedical, Inc.

Sex: All·Age: 45+

Code: NCT07373067·Phase 1

The Gut - PRO Study

for Alzheimer Disease

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07413744·Phase 2

Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease

for Alzheimer Disease

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 55 - 85

Code: NCT07756294·Phase 2

Multisensory 40-Hz Stimulation for Alzheimer's Disease

for Alzheimer Disease

Sponsor: Beijing Tiantan Hospital

Sex: All·Age: 45 - 75

Code: NCT07758751

A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease

for Alzheimer Disease

10 sites incl. Irvine

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07787169·Phase 1

A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease

for Healthy Volunteers

10 sites incl. Irvine

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07787182·Phase 1

Validation Study of the ExéSem Battery Designed to Differentiate the Contribution of Executive Functions in Semantic Disorders

for Alzheimer's Disease

Sponsor: Hospices Civils de Lyon

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT07573046

2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients

for Alzheimer Disease

1 site in Nashville

Sponsor: MTI Biotech Inc

Sex: All·Age: 55 - 85

Code: NCT06432166·Phase 1, Phase 2

A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration

for Alzheimer's Disease

1 site in Anaheim

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07780383·Phase 1

Presence of Anti-RACH Antibodies and Neurocognitive Disorder in Myasthenic or Alzheimers's Patients.

for Alzheimer Disease

Sponsor: Centre Hospitalier Universitaire de Nice

Sex: All·Age: 18+

Code: NCT06523296

Apply to this trial

A Study of GSM-779690T in Healthy Adult Participants

for Healthy Adult Participants

Sponsor: Acta Pharmaceuticals

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07690228·Phase 1

Evaluate the Concordance Between PET Imaging of [18F]-APN-1607 Injection and Postmortem Brain Tissue Tau Pathology in Individuals With HV and MCI or AD.

for Alzheimer's Disease

Sponsor: JYAMS PET Research & Development Limited

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07752784·Phase 3

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A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL921 in Healthy Participants and Participants With Alzheimer's Disease

for Alzheimer's Disease

Sponsor: Denali Therapeutics Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07758595·Phase 1

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Alzheimer's Disease Research Center (ADRC) PET Component Study

for Alzheimer Disease

1 site in New York

Sponsor: Patrick Lao

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07758660·Phase 2

Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease

for Alzheimer&Amp

1 site in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 65 - 85

Code: NCT06835283

Apply to this trial

Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation

for Down Syndrome (DS)

Sponsor: Michael Rafii, MD, PhD

Sex: All·Age: 35 - 50

Code: NCT06911944·Phase 4

A Study to Evaluate the Safety, Tolerability, and Efficacy of TML-6 in Participants With Early Alzheimer's Disease

for Alzheimer Disease

Sponsor: Merry Life Biomedical Co., Ltd.

Sex: All·Age: 60 - 85

Code: NCT07612150·Phase 2

Using Artificial Intelligence to Detect Early Signs of Alzheimer's Disease in People With Memory Concerns

for Subjective Cognitive Decline

Sponsor: IRCCS San Raffaele

Sex: All·Age: 40+

Code: NCT07652931

Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease

for Alzheimer Disease

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06045988

REPAIR Sleep Study

for Cognition Disorder

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT07572565

A Retrospective Database Study for the Development and Validation of Algorithms for Intracerebral Hemorrhage and Seizures in Alzheimer's Disease

for Alzheimer's Disease

Sponsor: Eisai Inc.

Sex: All·Age: All ages

Code: NCT07723950

A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease

for Dementia, Alzheimer's Type

1 site in The Villages

Sponsor: Sanofi

Sex: All·Age: 55 - 85

Code: NCT07688213·Phase 2

Apply to this trial

Evaluation System for Lecanemab Efficacy Using Gold Electrode ECL to Monitor Alzheimer's Biomarkers

for Alzheimer Disease

Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Sex: All·Age: 50 - 90

Code: NCT07688460·Phase 4

Apply to this trial

Alzheimer's Tau Platform: Master Protocol

for Preclinical Alzheimer's Disease

1 site in San Francisco

Sponsor: Paul S. Aisen

Sex: All·Age: 50 - 80

Code: NCT06957418·Phase 2

Apply to this trial

Implementation of AIP Services for Older Adults With AD

for Alzheimer Disease

1 site in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07361601

Deep Cervical Lymphovenous Anastomosis for Moderate Alzheimer's Disease

for Alzheimer's Disease

Sponsor: Southwest Hospital, China

Sex: All·Age: 50 - 80

Code: NCT07658430

Masitinib in Patients With Mild Alzheimer's Disease

for Alzheimer Disease

Sponsor: AB Science

Sex: All·Age: 50+

Code: NCT05564169·Phase 3

Effects of Ginkgo Biloba on Blood Biomarkers in Mild Cognitive Impairment

for Mild Cognitive Impairment

Sponsor: Hanyang University

Sex: All·Age: 20+

Code: NCT07579689·Phase 4

AV-1980R (Tau Vaccine) in Preclinical Alzheimer's Disease (TAURUS-1980)

for Alzheimer Disease

6 sites incl. Boca Raton

Sponsor: Institute for Molecular Medicine

Sex: All·Age: 65 - 80

Code: NCT07158905·Phase 1

Apply to this trial

Music for Pain and Dementia

for Alzheimer Disease

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT07602283

Apply to this trial

Silkworm Pupa Powder Improves Alzheimer's Disease

for Alzheimer Disease

Sponsor: Zhejiang Provincial Tongde Hospital

Sex: All·Age: 50 - 90

Code: NCT07638449

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

for Alzheimer Disease

52 sites incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 55+

Code: NCT07602582·Phase 3

Apply to this trial

A Study of LY3439539 in Participants With Alzheimer's Disease

for Alzheimer Disease

1 site in Irvine

Sponsor: Eli Lilly and Company

Sex: All·Age: 50 - 85

Code: NCT07598370·Phase 1

Apply to this trial

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

for Alzheimer Disease

14 sites incl. Orange

Sponsor: Alpha Cognition, Inc

Sex: All·Age: 50+

Code: NCT07633470·Phase 4

Apply to this trial

A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

for Alzheimer's Disease

11 sites incl. Irvine

Sponsor: AbbVie

Sex: All·Age: 50 - 90

Code: NCT07599670·Phase 1, Phase 2

Apply to this trial

Wearables-and Blood-based Biomarkers-incorporated Modernisation of Circadian Rhythm Disruption Management in People Living With Alzheimer's Dementia: A Stepwise Study From Digital Inclusivity, Digital Therapy, to Digital Phenotyping and Biomarker Exploration

for Alzheimer Disease

Sponsor: China Medical University Hospital

Sex: All·Age: All ages

Code: NCT07222449

Allogeneic Adipose Tissue Derived-stem Cells in Alzheimer Disease

for Alzheimer Disease

Sponsor: University Hospital, Toulouse

Sex: All·Age: 50 - 85

Code: NCT07367815·Phase 1, Phase 2

Apply to this trial

Deep Learning on Amyloid Positons Emission Tomography

for Alzheimer Disease

Sponsor: Central Hospital, Nancy, France

Sex: All·Age: 18 - 99

Code: NCT07309107

Apply to this trial

Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease

for Alzheimer Disease

3 sites incl. Palo Alto

Sponsor: MMI (Medical Microinstruments, Inc.)

Sex: All·Age: 50+

Code: NCT07178210

Apply to this trial

Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases

for Frontotemporal Dementia, Behavioral Variant

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 50 - 80

Code: NCT07531732

Apply to this trial

Safety Assessment of Leronlimab and Its Effect on Brain Inflammation in Alzheimer's Disease

for Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease

1 site in New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 50+

Code: NCT07553338·Phase 2

Apply to this trial

Donanemab (LY3002813) Trial in Chinese Participants With Cognitively Unimpaired (Preclinical) Alzheimer's Disease

for Alzheimer Disease

Sponsor: Eli Lilly and Company

Sex: All·Age: 55 - 80

Code: NCT07571161·Phase 3

Apply to this trial

The Effect of Sequential Therapy on Alzheimer's Disease

for Mild Cognitive Impairment Due to Alzheimer Disease

Sponsor: Dongzhimen Hospital, Beijing

Sex: All·Age: 55 - 85

Code: NCT07768579

Apply to this trial

DIV-AD BARCELONA: Alzheimer's Blood-Based Biomakers for a Diverse Community

for Alzheimer Disease

Sponsor: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation

Sex: All·Age: 50 - 75·Accepts healthy volunteers

Code: NCT07521722

The Underlying Neural Mechanism of TMS in Improving the Imbalance of "Microbiota-brain-gut Axis" in Alzheimer 's Disease Population

for Alzheimer's Disease

Sponsor: Second Affiliated Hospital of Nanchang University

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07346794

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Alzheimer's disease clinical trials — common questions

Are alzheimer's disease clinical trials free to join?

Yes. Participating in a alzheimer's disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a alzheimer's disease clinical trial?

Each alzheimer's disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a alzheimer's disease trial near me?

Use the location controls above. We'll show recruiting alzheimer's disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many alzheimer's disease trials are recruiting right now?

We're currently tracking roughly 222 recruiting alzheimer's disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Alzheimer's disease trials by city

Boston, MA Chicago, IL Irvine, CA Miami, FL Los Angeles, CA Madison, WI Birmingham, AL Indianapolis, IN San Francisco, CA Anaheim, CA Boca Raton, FL Columbus, OH

Related specialties

Neurology Dementia care Brain disorders Geriatrics