Alzheimer's disease Clinical Trials

Recruiting alzheimer's disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat alzheimer's disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting alzheimer's disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting alzheimer's disease trials

Within

Transcranial Magnetic Stimulation for Alzheimer's Disease Treatment

for Alzheimer Disease

Sponsor: Universitat Oberta de Catalunya

Sex: All·Age: 60 - 75

Code: NCT03121066

Vagus Nerve Stimulation to Enhance Memory in Aging

for Alzheimer Disease

1 site in Stanford

Sponsor: Stanford University

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07214194

Electroconvulsive Therapy for Treatment of Alzheimer´s Disease

for Alzheimer's Disease

Sponsor: Central Institute of Mental Health, Mannheim

Sex: All·Age: 65+

Code: NCT02438202

Tricaprilin Phase 3 ALTER-AD (Alternative-Alzheimer Disease) Study

for Alzheimer Disease

Sponsor: Cerecin

Sex: All·Age: 55 - 85

Code: NCT05809908·Phase 3

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

for Alzheimer's Disease

Sponsor: Hoffmann-La Roche

Sex: All·Age: 55 - 80

Code: NCT07717411·Phase 3

Alzheimer's Tau Platform: Regimen A - AADvac1

for Preclinical Alzheimer's Disease

1 site in San Francisco

Sponsor: Paul S. Aisen

Sex: All·Age: 50 - 80

Code: NCT07167966·Phase 2

A Phase 2b/3 Clinical Study Evaluating T3D-959 in Mild-to-Moderate Alzheimer's Disease Subjects

for Alzheimer's Disease

1 site in Durham

Sponsor: T3D Therapeutics, Inc.

Sex: All·Age: 50 - 90

Code: NCT06964230·Phase 2, Phase 3

The Care for America's Aging Study

for Cognitive Impairment

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06021704

Validation Study of the ExéSem Battery Designed to Differentiate the Contribution of Executive Functions in Semantic Disorders

for Alzheimer's Disease

Sponsor: Hospices Civils de Lyon

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT07573046

The Gut - PRO Study

for Alzheimer Disease

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07413744·Phase 2

A Study of GSM-779690T in Healthy Adult Participants

for Healthy Adult Participants

Sponsor: Acta Pharmaceuticals

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07690228·Phase 1

Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease

for Alzheimer&Amp

1 site in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 65 - 85

Code: NCT06835283

Apply to this trial

Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation

for Down Syndrome (DS)

Sponsor: Michael Rafii, MD, PhD

Sex: All·Age: 35 - 50

Code: NCT06911944·Phase 4

A Study to Evaluate the Safety, Tolerability, and Efficacy of TML-6 in Participants With Early Alzheimer's Disease

for Alzheimer Disease

Sponsor: Merry Life Biomedical Co., Ltd.

Sex: All·Age: 60 - 85

Code: NCT07612150·Phase 2

Using Artificial Intelligence to Detect Early Signs of Alzheimer's Disease in People With Memory Concerns

for Subjective Cognitive Decline

Sponsor: IRCCS San Raffaele

Sex: All·Age: 40+

Code: NCT07652931

Cholinergic Deep Brain Stimulation for Alzheimer's Disease

for Alzheimer Disease, Early Onset

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 60 - 80

Code: NCT05882344

Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease

for Alzheimer Disease

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06045988

REPAIR Sleep Study

for Cognition Disorder

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT07572565

Evaluation System for Lecanemab Efficacy Using Gold Electrode ECL to Monitor Alzheimer's Biomarkers

for Alzheimer Disease

Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Sex: All·Age: 50 - 90

Code: NCT07688460·Phase 4

Apply to this trial

Alzheimer's Tau Platform: Master Protocol

for Preclinical Alzheimer's Disease

1 site in San Francisco

Sponsor: Paul S. Aisen

Sex: All·Age: 50 - 80

Code: NCT06957418·Phase 2

Apply to this trial

Implementation of AIP Services for Older Adults With AD

for Alzheimer Disease

1 site in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07361601

Deep Cervical Lymphovenous Anastomosis for Moderate Alzheimer's Disease

for Alzheimer's Disease

Sponsor: Southwest Hospital, China

Sex: All·Age: 50 - 80

Code: NCT07658430

A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease

for Dementia, Alzheimer's Type

Sponsor: Sanofi

Sex: All·Age: 55 - 85

Code: NCT07688213·Phase 2

Masitinib in Patients With Mild Alzheimer's Disease

for Alzheimer Disease

Sponsor: AB Science

Sex: All·Age: 50+

Code: NCT05564169·Phase 3

Effects of Ginkgo Biloba on Blood Biomarkers in Mild Cognitive Impairment

for Mild Cognitive Impairment

Sponsor: Hanyang University

Sex: All·Age: 20+

Code: NCT07579689·Phase 4

AV-1980R (Tau Vaccine) in Preclinical Alzheimer's Disease (TAURUS-1980)

for Alzheimer Disease

5 sites incl. Boca Raton

Sponsor: Institute for Molecular Medicine

Sex: All·Age: 65 - 80

Code: NCT07158905·Phase 1

Apply to this trial

Music for Pain and Dementia

for Alzheimer Disease

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT07602283

for Alzheimer Disease

Sponsor: China Medical University Hospital

Sex: All·Age: All ages

Code: NCT07222449

for Alzheimer Disease

Sponsor: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation

Sex: All·Age: 50 - 75·Accepts healthy volunteers

Code: NCT07521722

The Underlying Neural Mechanism of TMS in Improving the Imbalance of "Microbiota-brain-gut Axis" in Alzheimer 's Disease Population

for Alzheimer's Disease

Sponsor: Second Affiliated Hospital of Nanchang University

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07346794

Tele-Savvy for Latino Caregivers

for Alzheimer Disease

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT07290387

Apply to this trial

Biomarker-based Trial of NPC-1 for Alzheimer's Pathology

for Alzheimer Disease

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 55+

Code: NCT07236190·Phase 2

Apply to this trial

An Investigation Into the Feasibility of Beetroot Juice Supplementation in People Living With Alzheimer's Disease.

for Alzheimer's Disease

Sponsor: University of the West of Scotland

Sex: All·Age: 65 - 85

Code: NCT07258004

Use of Wearables for Identifying Factors Associated With Mild Cognitive Impairment and Early-Stage Alzheimer's Disease

for Mild Cognitive Impairment

Sponsor: Getúlio Vargas University Hospital

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07391436

A Study to Compare Two Different Sleep Tests in Participants With No Symptoms or Early Symptoms of Alzheimer's Disease

for Alzheimer's Disease

Sponsor: Eli Lilly and Company

Sex: All·Age: 55 - 85

Code: NCT07485153

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

for Alzheimer Disease

5 sites incl. Gilbert

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT06947941·Phase 3

Apply to this trial

Deep Cervical LymphatIc-Venous Anastomosis for Alzheimer's Disease

for Alzheimer Disease

Sponsor: General Hospital of Shenyang Military Region

Sex: All·Age: 50 - 80

Code: NCT07294885

Apply to this trial

Blood Biomarkers for Early and Accurate Diagnosis of Alzheimer's Disease in Primary Care

for Alzheimer Disease

Sponsor: Imperial College London

Sex: All·Age: 55+

Code: NCT07401849

Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder

for Alzheimer Disease

Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07314190

Learning Amyloid and Tau Results

for Alzheimer Disease

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 45 - 89·Accepts healthy volunteers

Code: NCT07222930

WeCareToFeedDysphagia to Reduce Care-partner Burden Full-scale RCT

for Caregiver Burden

1 site in Manhasset

Sponsor: Northwell Health

Sex: All·Age: 18+

Code: NCT07250113

Comparative Study of High Performance Low-Cost Optical Coherence Tomography (Stage 1B, 2 and 3)

for Optical Coherence Tomography of Retina

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07425106

Biomarkers of the Locus Coeruleus Nucleus: Links With Early Tau Pathology, Cognition and Alzheimer's Disease Risk

for Alzheimer Disease

Sponsor: University Hospital, Toulouse

Sex: All·Age: 60 - 100·Accepts healthy volunteers

Code: NCT07007208·Phase 2

Apply to this trial

Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders

for Major Depressive Disorder (MDD)

Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07239843

Lombard Cohort of Brain Health Services

for Subjective Cognitive Decline (SCD)

Sponsor: University of Milano Bicocca

Sex: All·Age: 18+

Code: NCT07457138

Apply to this trial

Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia

for Alzheimer s Disease

Sponsor: Sunnybrook Health Sciences Centre

Sex: All·Age: All ages

Code: NCT07279740·Phase 2

Apply to this trial

Repeat Intracerebroventricular Injections of RB-ADSC in Subjects Previously Treated in RBI Protocol RB-ADSC-02

for Alzheimer Disease

Sponsor: Regeneration Biomedical, Inc.

Sex: All·Age: 45+

Code: NCT07373067·Phase 1

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD)

for Alzheimer's Disease

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 75

Code: NCT07234942·Phase 1

Apply to this trial

Fisetin in Mild Alzheimer's Disease

for Alzheimer s Disease

Sponsor: Sunnybrook Health Sciences Centre

Sex: All·Age: 60+

Code: NCT07279714·Phase 2

Apply to this trial

Alzheimer's disease clinical trials — common questions

Are alzheimer's disease clinical trials free to join?

Yes. Participating in a alzheimer's disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a alzheimer's disease clinical trial?

Each alzheimer's disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a alzheimer's disease trial near me?

Use the location controls above. We'll show recruiting alzheimer's disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many alzheimer's disease trials are recruiting right now?

We're currently tracking roughly 222 recruiting alzheimer's disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Alzheimer's disease trials by city

Boston, MA Miami, FL Los Angeles, CA Madison, WI Birmingham, AL Chicago, IL Indianapolis, IN Irvine, CA San Francisco, CA Boca Raton, FL Columbus, OH Jacksonville, FL

Related specialties

Neurology Dementia care Brain disorders Geriatrics