Evaluate the Effectiveness of Intravitreal (IVT) Aflibercept Injection in Clinical Practice in naïve Patients With Neovascular Age-related Macular Degeneration (nAMD)
- Sponsor
- Bayer
- Study ID
- NCT03411941
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 50 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Eylea (Aflibercept, VEGF Trap-Eye, BAY86-5321) — DRUGIVT(Intravitreal) aflibercept treatment in routine clinical practice.
Study Details
There is a need to investigate the effectiveness of IVT aflibercept injection in routine clinical practice. The aim of this study is to collect 12-month real-world clinical data from treatment-naïve nAMD patients who started first-line treatment with IVT aflibercept injection, according to the SmPC (Summary of Product Characteristics) and the SERV (Spanish Society of Retina and Vitreous) guidelines. The effectiveness of IVT aflibercept will be assessed by the changes in VA (Visual Acuity) and CRT (Central Retinal Thickness) during treatment.
Key Dates
- Start date
- Feb 28, 2018
- Status verified
- Dec 2019
- Primary completion
- Mar 1, 2019
- Completion
- Mar 1, 2019
Study Design
- Enrollment
- 116 participants (actual)
Arms
- Arm: Treatment-naïve nAMD patientsPatient data for whom treatment with IVT aflibercept injection was initiated as first-line treatment according to the SmPC and the SERV Guideline, in treatment-naive patients with newly diagnosed of nAMD in routine clinical practice.
Primary Outcome Measure
Mean change in VA [ Time Frame: From baseline to month 12 ]
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