Synchronized Brain and Hand Stimulation After Stroke

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
Amit Sethi
Study ID
NCT04502290
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • Combined Non-invasive brain stimulation and functional electrical hand stimulation — DEVICE
    Participants will receive synchronously combined non-invasive brain stimulation (delivered via electrical/magnetic stimulation) with functional electrical stimulation (delivered via DS7A or Neuromove) of the weak hand

Study Details

Among the 795,000 individuals who sustain a stroke annually in the United States, 65% continue to experience moderate-to-severe impairments in one hand six months or more, which limits their ability to perform daily tasks. Currently there is dearth of understanding of the mechanisms of motor recovery after stroke. Understanding the mechanisms can potentially lead to the development of interventions to improve motor performance after stroke. The proposed study will examine how synchronously pairing brain and hand stimulation repeatedly affects the plasticity of the brain and motor performance after stroke. The knowledge gained from this study can be useful to develop interventions to improve hand movement after moderate-severe stroke.

Key Dates

Start date
Oct 1, 2020
Status verified
Jul 2025
Primary completion
May 22, 2024
Completion
May 22, 2024

Study Design

Enrollment
10 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Combined non-invasive brain and Functional Electrical Stimulation
    In this arm of the study participants will receive repeated non-invasive brain stimulation synchronously paired with FES

Primary Outcome Measure

Percent Change in Box and Block Test [ Time Frame: Baseline to 6 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
Neuromotor Recovery and Rehabilitation LabPittsburghPennsylvania15260-

Find similar trials in Pittsburgh, PA

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Neuromotor Recovery and Rehabilitation Lab· Pittsburgh, PA

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