Neural Mechanisms for Stopping Ongoing Speech Production (Study 2)
for Epilepsy
1 location in Pittsburgh
Sponsor: Lingyun Zhao
Sex: All·Age: 8 - 26
Code: NCT07713706·Enrolling By Invitation·Listed Jul 20, 2026
Neurology Clinical Trials in Pittsburgh, PA
As of September 2026, 54 paid clinical trials are recruiting for Neurology in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Pittsburgh
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
55 clinical trials for Neurology
·Clear filters· Email me when a new neurology trial opens in Pittsburgh, PA.
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
for Migraine
Drug: Elismetrep
Sites in Pittsburgh, Scottdale +111 more locations
Sponsor: Kallyope Inc.
Sex: All·Age: 18 - 75
Code: NCT07645924·Phase 3·Recruiting·Listed Jun 2026
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
for Parkinson's Disease
Drug: Prasinezumab
Sites in Pittsburgh, Philadelphia +48 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 50 - 85
Code: NCT07174310·Phase 3·Recruiting·Listed Sep 2025
A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury
for Traumatic Brain Injury
Sites in Pittsburgh, Philadelphia +11 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 18+
Code: NCT07455136·Recruiting·Listed Mar 2026
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
for Huntington Disease
Sites in Pittsburgh, Philadelphia +32 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 21 - 70
Code: NCT07326709·Phase 3·Recruiting·Listed Jan 2026
A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis
for Generalized Myasthenia Gravis
Drug: Remibrutinib
Sites in Pittsburgh +23 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18 - 85
Code: NCT06744920·Phase 3·Recruiting·Listed Dec 2024
A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy
for Multiple System Atrophy
Sites in Pittsburgh, Hershey +13 more locations
Sponsor: Teva Branded Pharmaceutical Products R&D LLC
Sex: All·Age: 30 - 75
Code: NCT06568237·Phase 2·Recruiting·Listed Aug 2024
An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy
for Multiple System Atrophy
Sites in Pittsburgh +7 more locations
Sponsor: Teva Branded Pharmaceutical Products R&D LLC
Sex: All·Age: 30+
Code: NCT07197866·Phase 2·Recruiting·Listed Sep 2025
Deep Brain Stimulation (DBS) Retrospective Outcomes Study
for Parkinson Disease
Sites in Pittsburgh +6 more locations
Sponsor: Boston Scientific Corporation
Sex: All·Age: All ages
Code: NCT03664609·Recruiting·Listed Sep 2018
A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease
for Huntington Disease
Sites in Pittsburgh, Philadelphia +3 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 25 - 65
Code: NCT06826612·Phase 1, Phase 2·Recruiting·Listed Feb 2025
A Study to Evaluate the SENSE Device's Ability to Detect TBI
for Traumatic Brain Injury
Sites in Pittsburgh +5 more locations
Sponsor: Sense Diagnostics, LLC
Sex: All·Age: 22+·Accepts healthy volunteers
Code: NCT06828107·Recruiting·Listed Feb 2025
Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients
for Mild Cognitive Impairment (MCI)
1 location in Pittsburgh
Sponsor: Pravat Mandal
Sex: All·Age: 55 - 80
Code: NCT07583251·Phase 1·Recruiting·Listed May 2026
Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways
for Stroke
1 location in Pittsburgh
Sponsor: Peter C. Gerszten, MD
Sex: All·Age: 21 - 75·Accepts healthy volunteers
Code: NCT07401186·Recruiting·Listed Feb 2026
Strategy Training for Optimizing Attention for Individuals With Spatial Neglect
for Stroke
1 location in Pittsburgh
Sponsor: University of Pittsburgh
Sex: All·Age: 18+
Code: NCT07331896·Recruiting·Listed Jan 2026
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
for Stroke
Sites in Pittsburgh, Hershey +38 more locations
Sponsor: Yale University
Sex: All·Age: 18+
Code: NCT05338697·Recruiting·Listed Apr 2022
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
for Alzheimers Disease
Sites in Pittsburgh +12 more locations
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06647498·Phase 2, Phase 3·Recruiting·Listed Oct 2024
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
for Alzheimers Disease
Sites in Pittsburgh +12 more locations
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05552157·Phase 2, Phase 3·Recruiting·Listed Sep 2022
Subcortical Arousal in Perceptual Awareness
for Epilepsy
Sites in Pittsburgh +7 more locations
Sponsor: Yale University
Sex: All·Age: 13+
Code: NCT06934356·Recruiting·Listed Apr 2025
The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study
for Obstructive Sleep Apnea
Sites in Pittsburgh +3 more locations
Sponsor: California Pacific Medical Center Research Institute
Sex: All·Age: 55 - 85
Code: NCT05988385·Recruiting·Listed Aug 2023
The Fourth Left Atrial Appendage Occlusion Study
for Atrial Fibrillation
Sites in Pittsburgh, Hershey +45 more locations
Sponsor: Hamilton Health Sciences Corporation
Sex: All·Age: 18+
Code: NCT05963698·Recruiting·Listed Jul 2023
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
for Cognitive Impairment, Mild
Sites in Pittsburgh, Philadelphia +89 more locations
Sponsor: Duke University
Sex: All·Age: 75+·Accepts healthy volunteers
Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020
Improving Access to Care for Veterans With Memory Loss
for Alzheimer Disease
1 location in Pittsburgh
Sponsor: VA Pittsburgh Healthcare System
Sex: All·Age: 18+
Code: NCT07117162·Recruiting·Listed Aug 2025
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
for Autoimmune Disease
Drug: Nivolumab
Sites in Pittsburgh +40 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03816345·Phase 1·Recruiting·Listed Jan 2019
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
for Intracerebral Hemorrhage
Sites in Pittsburgh, Hershey +140 more locations
Sponsor: Yale University
Sex: All·Age: 18+
Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019
Dominantly Inherited Alzheimer Network (DIAN)
for Alzheimer's Disease
Sites in Pittsburgh +6 more locations
Sponsor: Washington University School of Medicine
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT00869817·Recruiting·Listed Mar 2009
An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation
for Stroke
Sites in Pittsburgh +1 more location
Sponsor: University of Pittsburgh
Sex: All·Age: 18+
Code: NCT04187131·Recruiting·Listed Dec 2019
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
for Parkinson Disease
Sites in Pittsburgh, Philadelphia +28 more locations
Sponsor: Michael J. Fox Foundation for Parkinson's Research
Sex: All·Age: 30+·Accepts healthy volunteers
Code: NCT04477785·Recruiting·Listed Jul 2020
Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis
for Stroke
1 location in Pittsburgh
Sponsor: Marco Capogrosso
Sex: All·Age: 22 - 70
Code: NCT07153536·Recruiting·Listed Sep 2025
University of Pittsburgh Brain Health Initiative
for Traumatic Brain Injury
1 location in Pittsburgh
Sponsor: David Okonkwo, MD, PhD
Sex: Male·Age: 29 - 59·Accepts healthy volunteers
Code: NCT04708613·Recruiting·Listed Jan 2021
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
for Stroke
1 location in Pittsburgh
Sponsor: University of Pittsburgh
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06458153·Recruiting·Listed Jun 2024
Trial-Ready Cohort-Down Syndrome (TRC-DS)
for Down Syndrome
Sites in Pittsburgh +17 more locations
Sponsor: University of Southern California
Sex: All·Age: 25 - 55
Code: NCT04165109·Recruiting·Listed Nov 2019
Late Onset Alzheimer's Disease
for Alzheimer Disease
Sites in Pittsburgh +11 more locations
Sponsor: Columbia University
Sex: All·Age: 55+·Accepts healthy volunteers
Code: NCT05010603·Recruiting·Listed Aug 2021
mSCI: Mobile Health App for Veterans With SCI and Caregivers
for Spinal Cord Injuries (SCI)
1 location in Pittsburgh
Sponsor: University of Pittsburgh
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07269977·Recruiting·Listed Dec 2025
Cortical Recording and Stimulating Array Brain-Machine Interface
for Tetraplegia
Sites in Pittsburgh +1 more location
Sponsor: Michael Boninger
Sex: All·Age: 22 - 70
Code: NCT01894802·Recruiting·Listed Jul 2013
Genes and Environment in Multiple Sclerosis
for Multiple Sclerosis
Sites in Pittsburgh +2 more locations
Sponsor: Columbia University
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT01353547·Recruiting·Listed May 2011
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
for Stroke
1 location in Pittsburgh
Sponsor: Jorge Gonzalez-Martinez
Sex: All·Age: 18 - 75
Code: NCT06303869·Recruiting·Listed Mar 2024
Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding
for Epilepsy
1 location in Pittsburgh
Sponsor: University of Pittsburgh
Sex: Female·Age: 18 - 45
Code: NCT05450978·Recruiting·Listed Jul 2022
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
for Stroke
Sites in Pittsburgh +24 more locations
Sponsor: University of Cincinnati
Sex: All·Age: 18+
Code: NCT05911568·Recruiting·Listed Jun 2023
Virtual Peer Coaching in Manual Wheelchair Skills
for Wheelchair
1 location in Pittsburgh
Sponsor: University of Pittsburgh
Sex: All·Age: 18+
Code: NCT06295146·Recruiting·Listed Mar 2024
Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
for Delirium
Sites in Pittsburgh, Philadelphia +5 more locations
Sponsor: University of Michigan
Sex: All·Age: 70+
Code: NCT05929703·Recruiting·Listed Jul 2023
Stroke Thrombectomy and Aneurysm Registry
for Stroke
Sites in Pittsburgh, York +52 more locations
Sponsor: Medical University of South Carolina
Sex: All·Age: 1 - 120
Code: NCT04994756·Recruiting·Listed Aug 2021
Top Research Study Locations in Pittsburgh
Researchers run research studies in Pittsburgh, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pittsburgh | Stroke, Traumatic Brain Injury, Dementia | 158 |
| UPMC Hillman Cancer Center | Melanoma, Metastatic Malignant Solid Neoplasm, Acute Myeloid Leukemia | 148 |
| University of Pittsburgh Medical Center | Chronic Pancreatitis, Cystic Fibrosis, Advanced Solid Tumor | 130 |
| Allegheny General Hospital | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Pulmonary Hypertension | 62 |
| Children's Hospital of Pittsburgh of UPMC | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia | 59 |
| UPMC Children's Hospital of Pittsburgh | Fabry Disease, Cerebral Palsy, Congenital Bone Marrow Failure Syndromes | 52 |
| Allegheny Health Network | Brain Tumor, Breast Cancer, Colorectal Cancer | 32 |
| UPMC-Passavant Hospital | Anatomic Stage II Breast Cancer AJCC v8, Recurrent Endometrial Carcinoma, Stage IV Lung Cancer AJCC v8 | 32 |
| UPMC-Saint Clair Hospital Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma, Stage III Laryngeal Cancer AJCC v8 | 27 |
| UPMC-Saint Margaret | Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | 25 |
| West Penn Hospital | Large B-cell Lymphoma, Stage IV Colorectal Cancer AJCC v8, Acute Lymphoblastic Leukemia (ALL) | 23 |
| UPMC-Magee Womens Hospital | Anatomic Stage II Breast Cancer AJCC v8, Recurrent Endometrial Carcinoma, Anatomic Stage I Breast Cancer AJCC v8 | 21 |
| UPMC | Focal Epilepsy, ASD - Atrial Septal Defect, Advanced Melanoma | 20 |
| UPMC Presbyterian | Acute Kidney Injuries, Aneurysm of Aorta, Thoracic, Aneurysmal Disease | 20 |
| UPMC-Shadyside Hospital | Head and Neck Squamous Cell Carcinoma, Metastatic Renal Cell Carcinoma, Stage II Lip and Oral Cavity Cancer AJCC v8 | 20 |
| UPMC Presbyterian Hospital | Abdominal Surgery, Acute Ischemic Stroke, Acute Myocardial Infarction | 19 |
| VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA | Cardiovascular Diseases, Stroke, Acute Kidney Injury | 19 |
| Children's Hospital of Pittsburgh | Diabetes Mellitus, Type 2, Hyperglycemia, Physical Inactivity | 16 |
| University of Pittsburgh Cancer Institute (UPCI) | Head and Neck Squamous Cell Carcinoma, Metastatic Renal Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma | 16 |
| UPMC Magee-Womens Hospital | ADHD, Behavioral Intervention, Breast Cancer | 9 |
| University of Pittsburgh School of Medicine | Adolescents, Anorexia Nervosa, Bipolar Disorder (BD) | 9 |
| AHN Allegheny General Hospital | Breast Cancer, Cancer, Carcinoma, Non-Small-Cell Lung | 8 |
| AHN West Penn Hospital | Malignant Mesothelioma, Malignant Pleural Effusion, Metastasis to Pleura | 8 |
| University of Pittsburgh Medical Center (UPMC) | ALS, ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis | 8 |
| UPMC Shadyside Hospital | Abdominal Surgery, Dementia, Harm Reduction | 7 |
Active & Upcoming Studies in Pittsburgh (2026)
Recruiting trials in Pittsburgh grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (397 active studies)
- Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE · University of Pittsburgh
- Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma · Phase 1 · National Cancer Institute (NCI)
Neurology & pain (82 active studies)
- Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE · University of Pittsburgh
- Psilocybin After Trauma Surgery for Pain · Phase 1 · Trent Emerick
Cardiovascular (73 active studies)
- Prediction and Prevention of Postoperative Mortality and Morbidity · University of Pittsburgh
- TEPH: Telaglenastat Efficacy in Pulmonary Hypertension · Phase 1, Phase 2 · Chan, Stephen, MD, PhD
Diabetes & metabolic (39 active studies)
- Technology Knowledge Optimization for Type 1 Diabetes in Schools · University of Pittsburgh
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Mental health & behavior (38 active studies)
Pediatric (19 active studies)
- Hypoxic Red Blood Cells in Sickle Cell Anemia · Hemanext
- A Multicenter Study to Assess the Feasibility of 5-Aminolevulinic Acid (5-ALA) in Pediatric Brain Tumor Patients · Phase 2 · Costas Hadjipanayis
HIV / STI (10 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (7 active studies)
Eye & vision (3 active studies)
- A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults · Astellas Pharma Global Development, Inc.
- The Effect of Rinsing on Ocular Inflammation and Symptoms in Patients With Dry Eye Disease · Rinsada
Common conditions studied in Pittsburgh
- Breast Cancer (25 active studies)
- Cancer (19 active studies)
- Melanoma (17 active studies)
- Stroke (17 active studies)
- Endometrial Cancer (16 active studies)
- Ovarian Cancer (16 active studies)
Leading research sponsors in Pittsburgh
- University of Pittsburgh
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Pittsburgh?
There are approximately 1,242 recruiting clinical trials in Pittsburgh, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Pittsburgh pay participants?
Most recruiting trials in Pittsburgh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Pittsburgh?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Pittsburgh?
The most common conditions under active study in Pittsburgh include Breast Cancer (25), Cancer (19), Melanoma (17), Stroke (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Pittsburgh?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Pittsburgh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Pittsburgh?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Pittsburgh?
Recruiting research sites in Pittsburgh include University of Pittsburgh, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Pittsburgh right now?
The largest active categories in Pittsburgh are Cancer & tumors (397), Neurology & pain (82), Cardiovascular (73). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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Trials by condition in Pittsburgh
Conditions in Neurology (Pittsburgh, PA)
Stroke· 21Traumatic brain injury (TBI)· 10Alzheimer's disease· 7Dementia· 7Spinal cord injury· 5Parkinson's disease· 4Multiple sclerosis· 4Epilepsy· 4Mild cognitive impairment (MCI)· 3Huntington disease· 2Multiple system atrophy· 2Aphasia· 2Cognitive impairment / decline· 2Migraine· 1Essential tremor· 1Myasthenia gravis· 1