"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Study ID
NCT04690972
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Blood sample during surgery — PROCEDURE
    During the hepato-bilio-pancreatic surgery, blood is drawn.
  • Taking an additional biopsy — PROCEDURE
    As part of the treatment, an additional biopsy is executed and blood is drawn.
  • Blood sample during diagnostic test — DIAGNOSTIC_TEST
    Blood sample as part of the care

Study Details

Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.

Key Dates

First listed
Dec 31, 2020
Start date
Jan 14, 2021
Status verified
Feb 2026
Primary completion
Jan 18, 2021
Completion
Sep 2, 2029

Study Design

Enrollment
800 participants (estimated)

Arms

  • Arm: Hepato-bilio-pancreatic surgery
    Patients whom hepato-bilio-pancreatic surgery is indicated as part of the care
  • Arm: biopsy of the hepatic parenchyma
    Patients whom a biopsy of the hepatic parenchyma, one or more hepatic nodules or a loco-regional treatment is indicated as part of the care
  • Arm: Viral chronic infection
    Patients with a viral chronic liver disease

Primary Outcome Measure

Surgery for a hepato-bilio-pancreatic issue [ Time Frame: through study completion, an average of 8 year ]

Central Contacts

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