Project AMD: Comprehensive Characterisation of Age-Related Macular Degeneration and Its Progression

Sponsor
Center for Eye Research Australia
Study ID
NCT04739319
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • N/A Observational study — OTHER
    N/A Observational study

Study Details

Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss worldwide, and nearly two million Australians have some signs of AMD. This proposed project is a prospective, observational study that seeks to to understand the underlying aetiology of AMD, factors associated with differences between age-related macular degeneration (AMD) phenotypes or severities, or between AMD and healthy individuals. It also seeks to understand the natural history of AMD progression and the factors associated with the rate of progression. In this project, the disease phenotype, genotype and severity and rate of progression will be determined based on non-invasive clinical imaging or functional assessment of the retina, from obtaining biological samples from the participants, or from patient-reported outcomes.

Key Dates

First listed
Feb 4, 2021
Start date
Feb 2, 2021
Status verified
Feb 2024
Primary completion
Nov 30, 2040
Completion
Nov 30, 2040

Study Design

Enrollment
2,500 participants (estimated)

Arms

  • Arm: Age-Related Macular Degeneration
    Participants with Age-Related Macular Degeneration

Primary Outcome Measure

Investigate the underlying aetiology of Age-Related Macular Degeneration [ Time Frame: Up to 20 years ]

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