Carelizumab Combined With Regorafenib in the Treatment of HCC(CARE-2020)
- Sponsor
- Nanfang Hospital, Southern Medical University
- Study ID
- NCT04806243
- Phase
- PHASE2
- Status
- Unknown
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Regorafenib Pill&Camrelizumab — DRUGRegorafenib,80 mg,QD,Q3w Camrelizumab,200 mg,IV,Q3w
Study Details
To investigate the efficacy and safety of carelizumab combined with regorafenib in second-line treatment for patients with primary hepatocellular carcinoma.
Key Dates
- Start date
- May 6, 2021
- Status verified
- Apr 2021
- Primary completion
- Jan 1, 2022
- Completion
- Jan 1, 2022
Study Design
- Enrollment
- 69 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Carelizumab Combined With Regorafenib arm
Primary Outcome Measure
os(overall survival) [ Time Frame: 21 days ]
Related Studies
- Dose-defining Study of Tirapazamine Combined With Embolization in Liver CancerPHASE1/PHASE2 · Recruiting · Teclison Ltd. · Palo Alto, California
- Combination of TATE and PD-1 Inhibitor in Liver CancerPHASE2 · Recruiting · Teclison Ltd. · Orange, California
- Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal MalignanciesPHASE1/PHASE2 · Recruiting · Anwaar Saeed · Westwood, Kansas
- Y90 Radioembolization Dose Delivery and Radiation Exposure AssessmentRecruiting · University of Tennessee · Knoxville, Tennessee