Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)

Part of paid clinical trials in Lexington, Kentucky.

Sponsor
Gopalkumar Rakesh
Study ID
NCT05295953
Status
Completed

Conditions

  • Hiv
  • Tobacco Smoking

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • TBS — DEVICE
    Four sessions of TBS at 120 % resting motor threshold, delivered using MagVenture B65 A/P coil, each lasting 10 minutes and separated by 50 minutes intervals. Targeting will be done using neuronavigation and processed resting state brain scan.
  • Sham TMS — DEVICE
    Four sessions of sham TMS delivered using MagVenture B65 A/P coil.

Study Details

To demonstrate whether four sessions of TBS improves attentional bias and craving in PLWHA smokers compared to four sessions of sham stimulation. We hypothesize 4 sessions of TBS to the left DLPFC will significantly improve attentional bias and craving for smoking cues compared to neutral cues in a population of subjects who are smokers with HIV/AIDS compared to sham stimulation.

Key Dates

First listed
Mar 25, 2022
Start date
Apr 1, 2022
Status verified
Oct 2025
Primary completion
Jul 31, 2024
Completion
Jul 31, 2024

Study Design

Enrollment
4 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: TBS (Theta burst stimulation)
    Four sessions of TBS in one day
  • Placebo Comparator: Sham TMS
    Four sessions of sham TMS

Primary Outcome Measure

Gaze Fixation on Smoking Cues [ Time Frame: On Day 1 of the study ]

Locations (2)

FacilityCityStateZIPSite coordinators
245 Fountain CourtLexingtonKentucky40513-
University of KentuckyLexingtonKentucky40513-

Find similar trials in Lexington, KY

By condition
HIV
By specialty
Infectious disease
By research site
245 Fountain Court· Lexington, KYUniversity of Kentucky· Lexington, KY

Related Studies