Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression

Sponsor
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Study ID
NCT05465252
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • Krill Oil — DIETARY_SUPPLEMENT
    Qualified subjects start to take supplementation from Day 1 in the trial. Specifically, subjects from Intervention group take 4 capsules of krill oil per day.
  • Olive Oil — DIETARY_SUPPLEMENT
    Qualified subjects start to take placebo from Day 1 in the trial. Specifically, subjects from placebo group take 4 capsules of olive oil, which has the same color and smell as the krill oil.

Study Details

This randomized, double-blind, placebo-controlled study aims to evaluate the effect of krill oil supplementation in patients with dry age-related macular degeneration (AMD). Participants will receive 4 capsules of krill oil or placebo daily for a period of 3 months. Outcomes will be evaluated after 3-month treatment to assess differences between the two study groups.

Key Dates

First listed
Jul 19, 2022
Start date
Oct 17, 2025
Status verified
Dec 2025
Primary completion
Mar 31, 2026
Completion
May 31, 2026

Study Design

Enrollment
24 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: krill oil
  • Placebo Comparator: olive oil

Primary Outcome Measure

Change in Macular Drusen Volume [ Time Frame: From enrollment to the end of follow-up at 3 months. ]

Central Contacts

Find similar trials

Nationwide
Age-related macular degeneration trialsOphthalmology trialsRetina trials

Related Studies