Sex and Gender-based Analysis of the Effectiveness of Advanced Therapies in Psoriatic Arthritis

Sponsor
Women's College Hospital
Study ID
NCT05954364
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Sex and gender are important factors that influence treatment response in PsA. The goal of this multi-centre observational study is to understand how sex and gender influence response to advanced therapies in psoriatic arthritis (PsA). The investigators hope to discover biological and socio-cultural mechanisms that explain the differences in treatment response between men and women with PsA. The study investigators plan to recruit patients from approximately 30 sites across the world. Men and women with active PsA will be assessed before and after they start advanced therapies and information will be collected about sex- and gender-related factors through questionnaires and physical examination. Physicians will assess the patient response to treatment. The investigators will compare the response to treatment in men and women and assess what biological and socio-cultural factors contribute to differences in treatment response.

Key Dates

First listed
Jul 20, 2023
Start date
Jan 23, 2023
Status verified
Jul 2023
Primary completion
Jun 30, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
540 participants (estimated)

Arms

  • Arm: Psoriatic Arthritis
    Patients with a rheumatologist-confirmed diagnosis of psoriatic arthritis who are initiating advanced therapy for peripheral musculoskeletal manifestations of psoriatic arthritis

Primary Outcome Measure

Achievement of the American College of Rheumatology (ACR) 20/50/70 [ Time Frame: Within 3-6 months ]

Central Contacts

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