Single Arm, Prospective, Multicenter Clinical Study of TACE With Adebrelimab and Bevacizumab for Unresectable Hepatocellular Carcinoma
- Sponsor
- The First Affiliated Hospital of Xiamen University
- Study ID
- NCT05970666
- Phase
- PHASE2
- Status
- Recruiting
Conditions
- Adebrelimab
- Bevacizumab
- Hepatocellular Carcinoma
- TACE
- Transformation
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- TACE with adebrelimab and bevacizumab — DRUGTACE treatment once; Adebrelimab: 20mg/kg, every 3 weeks (21 days); Bevacizumab; 15mg/kg, every 3 weeks (21 days);
Study Details
To evaluate the efficacy and safety of TACE combined with adebrelimab and bevacizumab transformation in unresectable hepatocellular carcinoma
Key Dates
- First listed
- Aug 1, 2023
- Start date
- Nov 15, 2023
- Status verified
- Feb 2024
- Primary completion
- Nov 15, 2026
- Completion
- Nov 15, 2026
Study Design
- Enrollment
- 71 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Single arm
Primary Outcome Measure
Objective response rate(ORR) [ Time Frame: Up to 2 years ]
Central Contacts
- Jianbo Chen15605921022
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