Tarlatamab (AMG 757) Expanded Access Protocol for Advanced Small Cell Lung Cancer

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Amgen
Study ID
NCT06064500
Status
Approved For Marketing

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tarlatamab — DRUG
    Tarlatamab will be administered as a 60-minute intravenous infusion with 1 mg step dose on cycle 1 day 1 followed by a 10 mg target dose on cycle 1 day 8 and cycle 1 day 15 in a 28-day cycle. Subsequent doses (10 mg) will be administered every 2 weeks.

Study Details

The primary objective of the study is to provide expanded access to and characterize the safety profile of tarlatamab in participants with advanced small cell lung cancer (SCLC) after two or more prior lines of treatment (including at least one platinum-based regimen). EA may still be available in countries outside of the United States.

Key Dates

Status verified
Mar 2025

Locations (9)

FacilityCityStateZIPSite coordinators
Yale School of MedicineNew HavenConnecticut06520-
Mount Sinai Comprehensive Cancer CenterMiami BeachFlorida33140-
Martin Memorial Health SystemStuartFlorida34994-
Nebraska Cancer SpecialistsOmahaNebraska68106-
Perlmutter Cancer Center at New York University Langone Hospital - 34th StreetNew YorkNew York10016-
The University of North Carolina at Chapel HillChapel HillNorth Carolina27599-
Fox Chase Cancer CenterPhiladelphiaPennsylvania19111-
University of VirginiaCharlottesvilleVirginia22903-
Cancer Care Northwest - SouthSpokaneWashington99202-

Find similar trials in New Haven, CT

By condition
Lung cancer
By specialty
OncologyLung oncologyLung disease
By research site
Yale School of Medicine· New Haven, CTMount Sinai Comprehensive Cancer Center· Miami Beach, FLMartin Memorial Health System· Stuart, FLNebraska Cancer Specialists· Omaha, NEPerlmutter Cancer Center at New York University Langone Hospital - 34th Street· New York, NYThe University of North Carolina at Chapel Hill· Chapel Hill, NC

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