Oncology Clinical Trials in New Haven, CT
As of July 2026, 210 paid clinical trials are recruiting for Oncology in New Haven, Connecticut. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in New Haven
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
211 clinical trials for Oncology
·Clear filters·↓ Download CSVA Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
About research studies in New Haven
New Haven has approximately 851 recruiting research studies across a wide range of therapeutic areas. Connecticut hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in New Haven
Researchers run research studies in New Haven, CT at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Yale University | Acute Myeloid Leukemia, Alcohol Use Disorder, Stage IV Lung Cancer AJCC v8 | 247 |
| Yale Cancer Center | Advanced Solid Tumor, Advanced Solid Tumors, NSCLC | 69 |
| Yale New Haven Hospital | Ischemic Stroke, Multiple Myeloma, NAFLD | 61 |
| Yale University School of Medicine | Alzheimers Disease, Alzheimers Disease, Familial, Colorectal Cancer | 60 |
| Yale School of Medicine | Epilepsy, Epilepsy (Treatment Refractory), Hemoglobinopathies | 42 |
| Smilow Cancer Center/Yale-New Haven Hospital | Ovarian Carcinoma, Advanced Hepatocellular Carcinoma, Anatomic Stage I Breast Cancer AJCC v8 | 19 |
| Connecticut Mental Health Center | Borderline Personality Disorder, Alcohol Use, Alcohol Use Disorder | 12 |
| Yale | AML, MDS, Acute Gastrointestinal Bleeding | 12 |
| Yale-New Haven Hospital | Acute Ischemic Stroke, Acute Myeloid Leukemia, Anemia, Sickle Cell | 12 |
| GSK Investigational Site | HIV Infections, Colonic Neoplasms, Gastrointestinal Neoplasms | 8 |
| Smilow Cancer Hospital at Yale New Haven | Advanced Solid Tumor, AML, AML With Mutated NPM1 | 8 |
| Yale Child Study Center | Speech, Anxiety Disorder of Adolescence, Autism | 8 |
| Yale New Haven Health | Chronic Kidney Diseases, Claudication, Critical Limb Ischemia | 7 |
| Musical Intervention Studios | COVID-19, Mental Health Issue, Alzheimer Disease | 6 |
| Smilow Cancer Hospital | Cancer, Sickle Cell Disease, Glioma, Malignant | 6 |
| Yale University, Yale Cancer Center | Breast Cancer, Endometrial Cancer, Ovarian Cancer | 6 |
| BLOOM | COVID-19, Mental Health Issue | 5 |
| Yale New Haven Health System | Aortic Stenosis, Heart Failure, ATTR Amyloidosis With Cardiomyopathy | 5 |
| Yale University Cancer Center | Advanced Solid Tumor, Advanced Solid Tumors, Anal Squamous Cell Carcinoma | 5 |
| Smilow Cancer Hospital - Yale New Haven Health | Breast Cancer, Advanced Non-Small Cell Lung Cancer, Advanced/Metastatic Solid Tumors | 4 |
| Yale New Haven Children's Hospital | Antibiotic Stewardship, Failed or Difficult Intubation, Sequela, Intubation Complication | 4 |
| Yale University School Of Medicine | Colorectal Neoplasms, Healthy Volunteers, Irritability Associated With Autism Spectrum Disorder | 4 |
| Yale University Yale Cancer Center | Advanced Solid Tumor, Advanced Solid Tumors, B Cell Lymphoma | 4 |
| Yale-New Haven Hospital-Yale Cancer Center | Advanced Breast Cancer, Breast Cancer, CRC | 4 |
| Clinical Trial Site | Generalized Myasthenia Gravis, Lichen Planopilaris, Relapsed/Refractory (R/R) Angioimmunoblastic T-cell Lymphoma (AITL) | 3 |
Active & Upcoming Studies in New Haven (2026)
Recruiting trials in New Haven grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (309 active studies)
- Unified Network for Integrated Fluid Collection at Yale · Yale University
- Efficacy and Safety Evaluation of VS-101 in Combination With Chemoradiotherapy in Patients With Head and Neck Cancer · Phase 2 · VSPharmTech Co.,Ltd.
Neurology & pain (45 active studies)
- The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain · Yale University
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Cardiovascular (40 active studies)
- Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health · Yale University
- Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants · University of Alabama at Birmingham
Diabetes & metabolic (36 active studies)
Mental health & behavior (25 active studies)
- The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease · Phase 2 · Yale University
- Multi-Site Trial of Tirzepatide for Smoking Cessation · Phase 2 · University of Southern California
Vaccines (11 active studies)
HIV / STI (11 active studies)
- RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry · University of Texas Southwestern Medical Center
- Integrating PrEP Decision Making Into Counseling in Sexual and Reproductive Health Clinics · Yale University
Pediatric (6 active studies)
- A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents · Yale University
- Human Milk Concentrating Device to Optimize Mother's Own Milk · Mother's Milk is Best
Common conditions studied in New Haven
- Advanced Solid Tumor (22 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (18 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Alcohol Use Disorder (16 active studies). Alcohol use disorder trials evaluate GLP-1 agonists, novel pharmacotherapies, and digital therapeutics as adjuncts to behavioral treatment.
- Acute Myeloid Leukemia (12 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Advanced Solid Tumors (12 active studies). Recruiting Advanced Solid Tumors studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Heart Failure (12 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
Leading research sponsors in New Haven
- Yale University
- National Cancer Institute (NCI)
- Children's Oncology Group
- Merck Sharp & Dohme LLC
- SWOG Cancer Research Network
Local regulations and guidelines
Clinical trials in Connecticut are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Connecticut research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in New Haven. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in New Haven
Hipa.ai aggregates every recruiting study in New Haven from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in New Haven?
There are approximately 851 recruiting clinical trials in New Haven, Connecticut listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in New Haven pay participants?
Most recruiting trials in New Haven compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in New Haven?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in New Haven?
The most common conditions under active study in New Haven include Advanced Solid Tumor (22), Breast Cancer (18), Alcohol Use Disorder (16), Acute Myeloid Leukemia (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in New Haven?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in New Haven on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in New Haven?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in New Haven?
Recruiting research sites in New Haven include Yale University, Yale Cancer Center, Yale New Haven Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in New Haven right now?
The largest active categories in New Haven are Cancer & tumors (309), Neurology & pain (45), Cardiovascular (40). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.