Visual Function Change in Wet Age-related Macular Degeneration Patients With Better Baseline Visual Acuity

Sponsor
Seoul National University Hospital
Study ID
NCT06330220
Phase
PHASE4
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

Although the number of wet AMD patients with the better visual acuity is increasing, the visual improvement in patients with the better vision may not be so significant after anti-vascular endothelial growth factor (VEGF) treatments because of 'ceiling effect'. The aim of current study is to investigate the improvement of visual function after aflibercept treatments using microperimetry in wet AMD patients with the better baseline visual acuity (≥20/40).

Key Dates

Start date
Feb 10, 2021
Status verified
Mar 2024
Primary completion
Feb 28, 2022
Completion
Feb 28, 2022

Study Design

Enrollment
12 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Aflibercept loading
    Administration of 2㎎ intravitreal aflibercept three times monthly after diagnosis

Primary Outcome Measure

Retinal sensitivity change after aflibercept treatment using microperimetry in wet age-related macular degeneration patients [ Time Frame: 12 weeks ]

Related Studies