A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight

Part of paid clinical trials in Chandler, Arizona.

Sponsor
Eli Lilly and Company
Study ID
NCT06683508
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • LY3549492 — DRUG
    Administered orally
  • Placebo — DRUG
    Administered orally

Study Details

The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to evaluate the effects of LY3549492 in adults with obesity or overweight. Participation in the study will last about one year.

Key Dates

Start date
Nov 13, 2024
Status verified
May 2026
Primary completion
Jan 7, 2026
Completion
May 4, 2026

Study Design

Enrollment
288 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: LY3549492 Dose 1
    Participants will receive LY3549492 orally
  • Experimental: LY3549492 Dose 2
    Participants will receive LY3549492 orally
  • Experimental: LY3549492 Dose 3
    Participants will receive LY3549492 orally
  • Experimental: LY3549492 Dose 4
    Participants will receive LY3549492 orally
  • Experimental: LY3549492 Dose 5
    Participants will receive LY3549492 orally
  • Placebo Comparator: Placebo
    Participants will receive Placebo orally

Primary Outcome Measure

Percent Change from Baseline in Body Weight [ Time Frame: Baseline, Week 36 ]

Locations (49)

FacilityCityStateZIPSite coordinators
The Institute for Liver Health II dba Arizona Clinical Trials - MesaChandlerArizona85225-
HOPE Research InstitutePhoenixArizona85032-
Headlands Research - ScottsdaleScottsdaleArizona85260-
The Institute for Liver Health II dba Arizona Liver Health-TucsonTucsonArizona85712-
NorCal Medical Research, IncGreenbraeCalifornia94904-
Velocity Clinical Research, Huntington ParkHuntington ParkCalifornia90255-
Peninsula Research AssociatesRolling Hills EstatesCalifornia90274-
Diablo Clinical Research, Inc.Walnut CreekCalifornia94598-
Stamford Therapeutics ConsortiumStamfordConnecticut06905-
Northeast Research Institute (NERI)Fleming IslandFlorida32003-
Indago Research & Health Center, IncHialeahFlorida33012-
New Horizon Research CenterMiamiFlorida33165-
Suncoast Clinical Research, Inc.New Port RicheyFlorida34652-
Charter Research - Winter ParkOrlandoFlorida32803-
Charter Research - Lady LakeThe VillagesFlorida32162-
Medical Research PartnersAmmonIdaho83406-
Great Lakes Clinical Trials - AndersonvilleChicagoIllinois60640-
Great Lakes Clinical Trials - RavenswoodChicagoIllinois60640-
NorthShore University Health SystemSkokieIllinois60077-
Iowa Diabetes and Endocrinology Research CenterWest Des MoinesIowa50266-
Cotton O'Neil Diabetes & EndocrinologyTopekaKansas66606-
L-MARC Research CenterLouisvilleKentucky40213-
KnownwellNeedhamMassachusetts02492-
Lucida Clinical TrialsNew BedfordMassachusetts02740-
Headlands Research - DetroitSouthfieldMichigan48034-
Arcturus Healthcare , PLC, Troy Internal Medicine Research DivisionTroyMichigan48098-
StudyMetrix ResearchCity of Saint PetersMissouri63303-
Clinvest Headlands LlcSpringfieldMissouri65807-
Las Vegas Medical ResearchLas VegasNevada89128-
Dent Neurologic InstituteAmherstNew York14226-
Velocity Clinical Research, SyracuseEast SyracuseNew York13057-
North Suffolk NeurologyPort Jefferson StationNew York11776-
Rochester Clinical Research, LLCRochesterNew York14609-
Medication ManagementGreensboroNorth Carolina27405-
Monroe Biomedical ResearchMonroeNorth Carolina28112-
Lucas Research, IncMorehead CityNorth Carolina28557-
Lucas Research, Inc.New BernNorth Carolina28562-
CTI Clinical Research CenterCincinnatiOhio45212-
Tribe Clinical Research, LLCGreenvilleSouth Carolina29607-
Quality Medical ResearchNashvilleTennessee37211-
IMA Clinical Research AustinAustinTexas78745-
FutureSearch Trials of DallasDallasTexas75251-
Velocity Clinical Research, DallasDallasTexas75230-
PlanIt Research, PLLCHoustonTexas77079-
Endeavor Clinical TrialsSan AntonioTexas78240-
Tekton Research - Fredericksburg RoadSan AntonioTexas78229-
Texas Valley Clinical ResearchWeslacoTexas78596-
Spectrum Medical, Inc.DanvilleVirginia24541-
Central Washington Health Services Association d/b/a Confluence HealthWenatcheeWashington98801-

Find similar trials in Chandler, AZ

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
The Institute for Liver Health II dba Arizona Clinical Trials - Mesa· Chandler, AZHOPE Research Institute· Phoenix, AZHeadlands Research - Scottsdale· Scottsdale, AZThe Institute for Liver Health II dba Arizona Liver Health-Tucson· Tucson, AZNorCal Medical Research, Inc· Greenbrae, CAVelocity Clinical Research, Huntington Park· Huntington Park, CA

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