Obesity / overweight Clinical Trials

Recruiting obesity / overweight studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat obesity / overweight. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting obesity / overweight studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting obesity / overweight trials

Within

Adiposity Distribution in Acute Respiratory Failure

for Acute Hypoxemic Respiratory Failure

1 site in Boston

Sponsor: Maurizio F. Cereda, MD

Sex: All·Age: 18 - 80

Code: NCT07019987

Simplifying Diet Tracking in a Digital Weight Loss Intervention

for Overweight

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT07601061

Can Two Dietary Interventions Maintain Weight Loss for 12 Months After GLP-1 Therapy in Adults With Overweight/Obesity?

for Obesity & Overweight

Sponsor: Knut Mai

Sex: All·Age: 18 - 70

Code: NCT07711548

SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus Standard Surgery in Patients With Obesity and Early-Stage Endometrial Cancer

for Endometrial Cancer

Sponsor: Hospital Universitari de Bellvitge

Sex: Female·Age: 18+

Code: NCT07462663·Phase 4

Nutrition Intervention Optimization to Better Utilize Resources and Support Health

for Diabete Type 2

1 site in Dallas

Sponsor: Tufts University

Sex: All·Age: 18+

Code: NCT07713836

AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight

for Obesity

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07668401·Phase 3

Human Models of Selective Insulin Resistance: Pancreatic Clamp

for Insulin Resistance

1 site in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 65

Code: NCT06558422·Phase 1

Digitally Enhanced Cognitive-Behavioral Therapy

for Depression in Adolescence

1 site in Aurora

Sponsor: Colorado State University

Sex: All·Age: 12 - 17

Code: NCT07569991

Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity

for Type 1 Diabetes Mellitus

Sponsor: Royal North Shore Hospital

Sex: All·Age: 18 - 70

Code: NCT06180616·Phase 2

Effect of a Mobile App for Obese Children on Eating Attitudes, Eating Awareness, and Healthy Eating Self-Efficacy

for Obesity

Sponsor: Cumhuriyet University

Sex: All·Age: 8 - 10

Code: NCT07289425

VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway

for Cardiovascular Diseases

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06320951·Phase 2

Obesity and Oral Diseases in Adult Patients

for Obesity

Sponsor: University of Bergen

Sex: All·Age: 20 - 70

Code: NCT04602572

Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation

for Weight Loss

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07535892

Effectiveness of Combined GLP-1/GIP Dual Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals

for Obesity

Sponsor: Acibadem University

Sex: All·Age: 18 - 65

Code: NCT07609160

Incisionless Suture Plications in a POSE2.0 Obesity Study

for Obesity

Sponsor: USGI Medical

Sex: All·Age: 22 - 65

Code: NCT06272201

Inhaled Nitric Oxide in Severe Obesity

for Obesity

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06675435

Comparison of Day Hospitalization Versus Full-Time Hospitalization in the Treatment of Severe Adolescent Obesity

for Severe Adolescent Obesity

Sponsor: Fondation Santé des Étudiants de France

Sex: All·Age: 12 - 20

Code: NCT07652190

GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward

for Obesity, Childhood

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12 - 18

Code: NCT06977438·Phase 4

Enhancing Mental and Physical Health of Women Veterans 3.0

for Cardiovascular Diseases

1 site in West Los Angeles

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT07356479

"Effectiveness of Supervised and Unsupervised mHealth-based Exercise Interventions on Clinical Outcomes in Adults With Type 2 Diabetes and Obesity Within a Primary Care Context"

for Diabetes Mellitus, Type 2

Sponsor: Escuela Universitaria de Osuna

Sex: All·Age: 30 - 65

Code: NCT07685080

Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women

for Obesity & Overweight

1 site in Little Rock

Sponsor: University of Arkansas

Sex: Female·Age: 50 - 65·Accepts healthy volunteers

Code: NCT07705724

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

for Obesity

1 site in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65

Code: NCT06299644

COMPASS 65+ - Community-based Physical Activity Snacks for Healthy Aging in Overweight and Obese Aged Adults

for Obesity & Overweight

Sponsor: University of Coimbra

Sex: All·Age: 65+

Code: NCT07289529

Ultrasound Assessment of Tongue Characteristics in Adolescents With Obesity and Obstructive Sleep Disorders

for Obesity & Overweight Sleep

Sponsor: Vrije Universiteit Brussel

Sex: All·Age: 12 - 18·Accepts healthy volunteers

Code: NCT07613944

BALANCE-OBS: Bofanglutide (GZR18) Versus Semaglutide in Latin American Adults With Overweight or Obesity

for Obesity & Overweight

Sponsor: Carnot Laboratories

Sex: All·Age: 18+

Code: NCT07622810·Phase 3

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

for Overweight

46 sites incl. Lancaster

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07668414·Phase 3

A Phase I Study of Single and Multiple Doses of HS-20136-2 Injection in Healthy or Obese Participants

for Obesity

Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07716241·Phase 1

Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes

for Obesity

Sponsor: University Hospital, Toulouse

Sex: All·Age: 45 - 70·Accepts healthy volunteers

Code: NCT07075133

Effect of Prebiotics in Saudi Adults With Type 2 Diabetes

for Type 2 Diabetes

Sponsor: Princess Nourah Bint Abdulrahman University

Sex: All·Age: 45 - 60·Accepts healthy volunteers

Code: NCT07464691

Puerto Rican Obesity Intervention for Men

for Obesity

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: Male·Age: 35+·Accepts healthy volunteers

Code: NCT06440551

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

for Obesity

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65

Code: NCT07224087·Phase 1

Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial

for Metabolic Syndrome

Sponsor: University of Zadar

Sex: All·Age: 20+·Accepts healthy volunteers

Code: NCT07314957

A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

for Obesity

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65

Code: NCT07398404·Phase 1, Phase 2

The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity

for Pre Diabetic

Sponsor: University of Primorska

Sex: All·Age: 18 - 70

Code: NCT07423065

Apply to this trial

Inherited and Environmental Risks Acting on Body Weight

for Genetics

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 20 - 45·Accepts healthy volunteers

Code: NCT07430852

The Role of Autoantibodies Against G-protein Coupled Receptors in Obesity

for Obesity

Sponsor: Claus Bogh Juhl

Sex: All·Age: 18 - 60

Code: NCT07542327

Diet and WB-EMS Effects in Obesity

for Obesity & Overweight

Sponsor: Firat University

Sex: All·Age: 18 - 65

Code: NCT07562724

eHealth Lifestyle Intervention To Enhance Outcomes in HFpEF

for Heart Failure and Preserved Ejection Fraction

Sponsor: Maimónides Biomedical Research Institute of Córdoba

Sex: All·Age: 18+

Code: NCT07661732

Trauma Therapy for Weight-Based Bullying in Children

for Pediatric Obesity

Sponsor: Western University

Sex: All·Age: 10 - 17

Code: NCT07685990

Sleep Evaluation Before and After Metabolic Surgery

for Obesity & Overweight

Sponsor: Catharina Ziekenhuis Eindhoven

Sex: All·Age: 18+

Code: NCT07693491

Effect of Tirzepatide on Recurrence of Atrial Fibrillation After Catheter Ablation in Obese Patients

for Atrial Fibrillation

Sponsor: Yunlong Wang

Sex: All·Age: 18 - 75

Code: NCT07715929·Phase 4

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

for Overweight

42 sites incl. Anniston

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07720271·Phase 3

Vibegron for ENergy Thinking and Resilience in Aging

for Obesity

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 45 - 75

Code: NCT06987383·Phase 3

The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED)

for Obesity & Overweight

1 site in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 30 - 65

Code: NCT07298915·Phase 3

Impact of Chia Seeds on Human Breast Milk Composition

for Obesity and Overweight

2 sites incl. Boston

Sponsor: University of Oklahoma

Sex: All·Age: 18 - 45

Code: NCT07343908

Augmenting Primary Care-Based Obesity Management With the Nutu™ Digital Health Platform

for Obesity & Overweight

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07404189

Weight Loss Goals and Satisfaction Survey

for Overweight and Obesity

Sponsor: Pennington Biomedical Research Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07541872

PLAY2CONTROL Study

for Type 2 Diabetes

1 site in Miami

Sponsor: University of Miami

Sex: All·Age: 5 - 21

Code: NCT07556679

The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health

for Preterm Birth

Sponsor: GrowBaby Life Project

Sex: Female·Age: 18+

Code: NCT07559773

Influence of the Use of Specific Nutritional Formulas on Time in Range in Patients With Type 2 Diabetes

for Type 2 Diabetes

Sponsor: Hospital Universitario San Ignacio

Sex: All·Age: 18+

Code: NCT07666581

Cardiometabolic Effects of the Recommended Daily Pecan Intake Dose

for Nutrition, Healthy

1 site in Athens

Sponsor: University of Georgia

Sex: All·Age: 25 - 75·Accepts healthy volunteers

Code: NCT07696403

A Study Comparing Continuous Glucose Monitoring Augmented Nutritional Counseling and Standard of Care Treatment Strategies in a Three-Month Nutrition Intervention

for Obesity & Overweight

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 13 - 17

Code: NCT07714759

Salivary Function and Dental Changes During GLP-1 Therapy

for Obesity

Sponsor: Bilecik Seyh Edebali Universitesi

Sex: All·Age: 18+

Code: NCT07720466

Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese

for Obesity and Overweight

8 sites incl. Los Angeles

Sponsor: Biomed Industries, Inc.

Sex: All·Age: 19 - 80

Code: NCT06732245·Phase 2

Online Group Programme on Mindful Eating During Medication-Supported Weight Loss

for Obesity & Overweight

Sponsor: Bern University of Applied Sciences

Sex: All·Age: 18+

Code: NCT07701291

Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health

for Hypertension (HTN)

Sponsor: Johns Hopkins University

Sex: All·Age: 30 - 79

Code: NCT07662616·EARLY_Phase 1

The NTU JO-SMART Study

for Knee Osteoarthristis

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18 - 75

Code: NCT07317310

Apply to this trial

The OAT Trail: The Obesity Anti-Coagulation Thromboprophylaxis Trial.

for Bariatric Surgery

Sponsor: University College Dublin

Sex: All·Age: 18+

Code: NCT07559643

Growth Hormone Resistance of Beta-cells

for Healthy

1 site in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 59

Code: NCT07581860

Effect of Oral Calcium Butyrate Supplementation in Obesity

for Obesity

Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Sex: All·Age: 18+

Code: NCT07583017

Obesity / overweight clinical trials — common questions

Are obesity / overweight clinical trials free to join?

Yes. Participating in a obesity / overweight clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a obesity / overweight clinical trial?

Each obesity / overweight study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a obesity / overweight trial near me?

Use the location controls above. We'll show recruiting obesity / overweight trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many obesity / overweight trials are recruiting right now?

We're currently tracking roughly 565 recruiting obesity / overweight trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Obesity / overweight trials by city

Boston, MA Birmingham, AL Los Angeles, CA Aurora, CO Chicago, IL Miami, FL Salt Lake City, UT Tallahassee, FL Ann Arbor, MI Gainesville, FL La Jolla, CA Palo Alto, CA

Related specialties

Endocrinology Metabolic health Weight loss